ESD (gene)

ESD
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 3FCX
Identifiers
Aliases	ESD , FGH, esterase D
External IDs	OMIM: 133280 MGI: 3781082 HomoloGene: 55623 GeneCards: ESD
Gene location (Human) Chr. Chromosome 13 (human) [1] Band 13q14.2 Start 46,771,256 bp [1] End 46,797,420 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in popliteal artery hair follicle germinal epithelium right coronary artery optic nerve ganglionic eminence retinal pigment epithelium gastric mucosa saphenous vein ascending aorta n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function S-formylglutathione hydrolase activity methylumbelliferyl-acetate deacetylase activity carboxylic ester hydrolase activity protein binding hydrolase activity hydrolase activity, acting on ester bonds identical protein binding Cellular component cytoplasm extracellular exosome endoplasmic reticulum lumen cytoplasmic vesicle cytosol Biological process formaldehyde catabolic process glutathione derivative biosynthetic process biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2098 100040682 Ensembl ENSG00000139684 n/a UniProt P10768 n/a RefSeq (mRNA) NM_001984 XM_036158963 RefSeq (protein) NP_001975 n/a Location (UCSC) Chr 13: 46.77 – 46.8 Mb n/a PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

S-formylglutathione hydrolase is an enzyme that in humans is encoded by the ESD gene. ^[4]

References

1. GRCh38: Ensembl release 89: ENSG00000139684 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: ESD esterase D/formylglutathione hydrolase".

Further reading

• Munier F, Balmer A, von Moos C, et al. (1991). "[Lausanne study of retinoblastoma, 1986-90: deletion of esterase D locus in a collective of 128 patients]". Klinische Monatsblätter für Augenheilkunde. 198 (5): 419–24. doi:10.1055/s-2008-1045999. PMID   1886375. S2CID   260193010.
• Young LJ, Lee EY, To HA, et al. (1988). "Human esterase D gene: complete cDNA sequence, genomic structure, and application in the genetic diagnosis of human retinoblastoma". Hum. Genet. 79 (2): 137–41. doi:10.1007/BF00280552. PMID   3164702. S2CID   25789298.
• Lee EY, Lee WH (1986). "Molecular cloning of the human esterase D gene, a genetic marker of retinoblastoma". Proc. Natl. Acad. Sci. U.S.A. 83 (17): 6337–41. Bibcode:1986PNAS...83.6337L. doi: 10.1073/pnas.83.17.6337 . PMC   386498 . PMID   3462698.
• Squire J, Dryja TP, Dunn J, et al. (1986). "Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13". Proc. Natl. Acad. Sci. U.S.A. 83 (17): 6573–7. Bibcode:1986PNAS...83.6573S. doi: 10.1073/pnas.83.17.6573 . PMC   386546 . PMID   3462714.
• Lee WH, Wheatley W, Benedict WF, et al. (1986). "Purification, biochemical characterization, and biological function of human esterase D." Proc. Natl. Acad. Sci. U.S.A. 83 (18): 6790–4. Bibcode:1986PNAS...83.6790L. doi: 10.1073/pnas.83.18.6790 . PMC   386595 . PMID   3462728.
• Cortivo P, Caenazzo L, Crestani C, et al. (1987). "Genetic study of red cell esterase D polymorphism by ultrathin layer isoelectric focusing. Distribution in the Veneto population (Italy)". Z. Rechtsmed. 98 (1): 39–42. doi:10.1007/BF00200384. PMID   3591015. S2CID   24618583.
• Eiberg H, Mohr J (1986). "Identity of the polymorphisms for esterase D and S-formylglutathione hydrolase in red blood cells". Hum. Genet. 74 (2): 174–5. doi:10.1007/BF00282085. PMID   3770744. S2CID   27095525.
• Tsuchida S, Fukui E, Ikemoto S (1994). "Molecular analysis of esterase D polymorphism". Hum. Genet. 93 (3): 255–8. doi:10.1007/BF00212018. PMID   7907313. S2CID   28243346.
• Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi: 10.1073/pnas.160270997 . PMC   16901 . PMID   10931946.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Saito S, Iida A, Sekine A, et al. (2003). "Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population". J. Hum. Genet. 48 (5): 249–70. doi: 10.1007/s10038-003-0021-7 . PMID   12721789.
• Sergeev AS, Agapova RK, Bogadel'nikova IV, Perel'man MI (2003). "[The use of discrete characters in discriminant analysis for diagnosis of pulmonary tuberculosis and for classification of patients differing in treatment efficiency based on polymorphisms at nine codominant loci-HP, GC, TF, PI, PGM1, GLO1, C3, ACP1 and ESD]". Genetika. 39 (7): 996–1002. PMID   12942785.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. Bibcode:2004Natur.428..522D. doi:10.1038/nature02379. PMC   2665288 . PMID   15057823.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.

External links

• Overview of all the structural information available in the PDB for UniProt : P10768 (S-formylglutathione hydrolase) at the PDBe-KB .