EVA1A | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | EVA1A , FAM176A, TMEM166, eva-1 homolog A, regulator of programmed cell death | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | MGI: 2385247 HomoloGene: 12969 GeneCards: EVA1A | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Eva-1 homolog A (C. elegans) is a protein that in humans is encoded by the EVA1A gene. [5]
Apoptosis regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene. BAX is a member of the Bcl-2 gene family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene.
60S ribosome subunit biogenesis protein NIP7 homolog is a protein that in humans is encoded by the NIP7 gene.
Programmed cell death protein 5 is a protein, originally identified as an apoptosis-accelerating protein, that in humans is encoded by the PDCD5 gene.
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein is a protein that in humans is encoded by the BNIPL gene.
Chemokine-like factor (CKLF) is a member of the CKLF-like MARVEL transmembrane domain-containing family of proteins that in humans is encoded by the CKLF gene. This gene is located on band 22.1 in the long arm of chromosome 16.
Transmembrane BAX inhibitor motif-containing protein 4 is a protein that in humans is encoded by the TMBIM4 gene. It is also known as humanGolgi anti-apoptotic protein (hGAAP) due to its function and sub-cellular localization.
Cell death-inducing DFFA-like effector b, also known as CIDEB, is a human gene.
Apoptosis-related protein 3 is a protein that in humans is encoded by the ATRAID gene.
Crumbs protein homolog 3 is a protein that in humans is encoded by the CRB3 gene.
Cell death activator CIDE-A is a protein that in humans is encoded by the CIDEA gene. Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids.
Protein wntless homolog, commonly known as Wntless, is encoded in humans by the WLS gene. Wntless is a receptor for Wnt proteins in Wnt-secreting cells.
Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene. Kremen1 is conserved in chordates including amphioxus and most vertebrate species. The protein is a type I transmembrane receptor of ligands Dickkopf1, Dickkopf2, Dickkopf3, Dickkopf4, EpCAM and Rspondin1.
Proline-rich transmembrane protein 2 is a protein that in humans is encoded by the PRRT2 gene.
STEAP family member 4 is a protein that in humans is encoded by the STEAP4 gene.
Vacuolar protein sorting 53 homolog is a protein that in humans is encoded by the VPS53 gene.
CKLF like MARVEL transmembrane domain-containing 7, previously termed chemokine-like factor superfamily 7, is a protein that in humans is encoded by the CMTM7 gene. This gene, which is located in band 22 on the short arm of chromosome 3, and the protein that it encodes belong to the CKLF-like MARVEL transmembrane domain-containing family. Through the process of alternative splicing, the CMTM7 gene encodes two isoforms, CMTM7-v1 and CMTM7-v2, with CMTM7-v1 being the main form expressed and studied. CMTM7 proteins are widely expressed in normal human tissues.
Mediator complex subunit 19 (Med19) is a protein that in humans is encoded by the MED19 gene.
Vestigial like family member 4 is a protein that in humans is encoded by the VGLL4 gene.
DDB1- and CUL4-associated factor 11 also known as WD Repeat Domain 23 (WDR23) is a protein that in humans is encoded by the DCAF11 gene.