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Heterochromatin is a tightly packed form of DNA or condensed DNA, which comes in multiple varieties. These varieties lie on a continuum between the two extremes of constitutive heterochromatin and facultative heterochromatin. Both play a role in the expression of genes. Because it is tightly packed, it was thought to be inaccessible to polymerases and therefore not transcribed; however, according to Volpe et al. (2002), and many other papers since, much of this DNA is in fact transcribed, but it is continuously turned over via RNA-induced transcriptional silencing (RITS). Recent studies with electron microscopy and OsO4 staining reveal that the dense packing is not due to the chromatin.
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References
- ↑ Haswell, Elizabeth S (2000). Chromatin remodeling at the Saccharomyces cerevisiae PHO5 promoter. OCLC 1023590117.
- ↑ Biology, Department of (May 4, 2017). "Elizabeth Haswell". Department of Biology. Retrieved February 1, 2022.
- ↑ "In plant cells, a conserved mechanism for perceiving mechanical force resides in unexpected location". ScienceDaily. Retrieved February 1, 2022.
- ↑ "Depth of perception - The Source - Washington University in St. Louis". The Source. July 29, 2021. Retrieved February 1, 2022.
- ↑ "How plants can respond to threats". ScienceDaily. Retrieved February 1, 2022.
- ↑ "524: Dr. Elizabeth Haswell: Researching How Plant Cells Sense and Respond to Internal Forces". People Behind the Science Podcast. October 21, 2019. Retrieved February 1, 2022.
- ↑ "Editorial Board". www.science.org. Retrieved February 1, 2022.
- ↑ "What if Plant Scientists were as Diverse as the Plants we Study?". Plantae. June 24, 2019. Retrieved February 1, 2022.
- ↑ Haswell, Elizabeth S (August 17, 2017). "The sustainable professor". eLife. 6: e31083. doi: 10.7554/eLife.31083 . ISSN 2050-084X. PMC 5577915 . PMID 28817377.
- ↑ Friesner, Joanna; Colón-Carmona, Adán; Schnoes, Alexandra M.; Stepanova, Anna; Mason, Grace Alex; Macintosh, Gustavo C.; Ullah, Hemayat; Baxter, Ivan; Callis, Judy; Sierra-Cajas, Kimberly; Elliott, Kiona (2021). "Broadening the impact of plant science through innovative, integrative, and inclusive outreach". Plant Direct. 5 (4): e00316. doi:10.1002/pld3.316. ISSN 2475-4455. PMC 8045900 . PMID 33870032.
- ↑ "DiversifyPlantSci". Haswell Lab. Retrieved February 1, 2022.
- ↑ "Chancellor Award for Advancement of Women Recipients | Page 5 | diversity.ucsf.edu". diversity.ucsf.edu. Retrieved February 1, 2022.
- ↑ "Alumni". Life Sciences Research Foundation. Retrieved February 1, 2022.
- ↑ "Elizabeth Haswell". HHMI. Retrieved February 1, 2022.
- ↑ "AAAS names eight Washington University faculty as 2021 fellows - The Source - Washington University in St. Louis". The Source. January 26, 2022. Retrieved February 1, 2022.
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