FAM127A

RTL8C
Identifiers
Aliases	RTL8C , CXX1, MAR8C, MART8C, Mar8, Mart8, FAM127A, family with sequence similarity 127 member A, SIRH5, retrotransposon Gag like 8C
External IDs	OMIM: 300213 MGI: 1920115 HomoloGene: 124163 GeneCards: RTL8C
Gene location (Human) Chr. X chromosome (human) [1] Band Xq26.3 Start 135,032,355 bp [1] End 135,033,546 bp [1]
Gene location (Mouse) Chr. X chromosome (mouse) [2] Band X|X A5 Start 52,609,999 bp [2] End 52,610,399 bp [2]
RNA expression pattern Bgee Top expressed in hypothalamus Brodmann area 10 dorsolateral prefrontal cortex amygdala frontal pole superior frontal gyrus prefrontal cortex More reference expression data BioGPS n/a
Gene ontology Molecular function GO:0001948 protein binding Cellular component membrane plasma membrane cellular component Biological process biological process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8933	72865
Ensembl	ENSG00000134590	ENSMUSG00000051851
UniProt	O15255	Q9D6I0
RefSeq (mRNA)	NM_003928 NM_001078171	NM_028375
RefSeq (protein)	NP_001071639	NP_082651
Location (UCSC)	Chr X: 135.03 – 135.03 Mb	Chr X: 52.61 – 52.61 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

CAAX box protein 1 is a protein that in humans is encoded by the FAM127A gene. ^{[5] [6] [7] [8]}

References

1. GRCh38: Ensembl release 89: ENSG00000134590 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051851 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Frattini A, Faranda S, Zucchi I, Vezzoni P (Jan 1998). "A low-copy repeat in Xq26 represents a novel putatively prenylated protein gene (CXX1) and its pseudogenes (DXS9914, DXS9915, and DXS9916)". Genomics. 46 (1): 167–9. doi:10.1006/geno.1997.5006. PMID   9403077.
6. Brandt J, Schrauth S, Veith AM, Froschauer A, Haneke T, Schultheis C, Gessler M, Leimeister C, Volff JN (Apr 2005). "Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals". Gene. 345 (1): 101–11. doi:10.1016/j.gene.2004.11.022. PMID   15716091.
7. Brandt J, Veith AM, Volff JN (Aug 2005). "A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes". Cytogenet Genome Res. 110 (1–4): 307–17. doi:10.1159/000084963. PMID   16093683. S2CID   38398479.
8. "Entrez Gene: FAM127A family with sequence similarity 127, member A".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC   2665286 . PMID   15772651.
• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi: 10.1016/j.cell.2006.03.032 . PMID   16713569.