FAM129A

NIBAN1
Identifiers
Aliases	NIBAN1 , C1orf24, NIBAN, GIG39, family with sequence similarity 129 member A, niban apoptosis regulator 1, FAM129A
External IDs	MGI: 2137237; HomoloGene: 62170; GeneCards: NIBAN1; OMA:NIBAN1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q25.3 Start 184,790,724 bp [1] End 184,974,508 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 G1- G2 Start 151,446,937 bp [2] End 151,597,690 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in saphenous vein parotid gland right ventricle vena cava myocardium cardiac muscle tissue of right atrium myocardium of left ventricle Skeletal muscle tissue of rectus abdominis seminal vesicula right coronary artery Top expressed in iris ciliary body granulocyte calvaria ascending aorta ankle lumbar spinal ganglion aortic valve conjunctival fornix lacrimal gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding molecular function Cellular component cytoplasm plasma membrane extracellular exosome membrane cytosol Biological process negative regulation of protein phosphorylation positive regulation of protein phosphorylation regulation of translation positive regulation of translation response to endoplasmic reticulum stress Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 116496 63913 Ensembl ENSG00000135842 ENSMUSG00000026483 UniProt Q9BZQ8 Q3UW53 RefSeq (mRNA) NM_052966 NM_022018 RefSeq (protein) NP_443198 NP_071301 Location (UCSC) Chr 1: 184.79 – 184.97 Mb Chr 1: 151.45 – 151.6 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein Niban is a protein that in humans is encoded by the FAM129A gene. ^{[5] [6] [7]} Paralogs of this protein include FAM129B, and FAM129C. ^[8]

References

1. GRCh38: Ensembl release 89: ENSG00000135842 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026483 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Cerutti JM, Delcelo R, Amadei MJ, Nakabashi C, Maciel RM, Peterson B, Shoemaker J, Riggins GJ (Apr 2004). "A preoperative diagnostic test that distinguishes benign from malignant thyroid carcinoma based on gene expression". J Clin Invest. 113 (8): 1234–42. doi:10.1172/JCI19617. PMC   385398 . PMID   15085203.
6. Maciel RM, Kimura ET, Cerutti JM (Jan 2006). "[Pathogenesis of differentiated thyroid cancer (papillary and follicular)]". Arq Bras Endocrinol Metabol. 49 (5): 691–700. doi: 10.1590/S0004-27302005000500009 . PMID   16444351.
7. "Entrez Gene: FAM129A family with sequence similarity 129, member A".
8. "NIBAN1 Gene - GeneCards | NIBA1 Protein | NIBA1 Antibody".

Further reading

• Majima S, Kajino K, Fukuda T, et al. (2000). "A novel gene "Niban" upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach". Jpn. J. Cancer Res. 91 (9): 869–74. doi:10.1111/j.1349-7006.2000.tb01027.x. PMC   5926447 . PMID   11011112.
• Sood R, Bonner TI, Makalowska I, et al. (2001). "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus". Genomics. 73 (2): 211–22. doi:10.1006/geno.2001.6500. PMID   11318611.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.
• Matsumoto F, Fujii H, Abe M, et al. (2007). "A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis". Hum. Pathol. 37 (12): 1592–600. doi:10.1016/j.humpath.2006.06.022. PMID   16949643.