FCHO2

FCHO2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2V0O
Identifiers
Aliases	FCHO2 , FCH domain only 2, FCH and mu domain containing endocytic adaptor 2
External IDs	OMIM: 613438 MGI: 3505790 HomoloGene: 9030 GeneCards: FCHO2
Gene location (Human)
Chr.	Chromosome 5 (human)
End	73,090,522 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	98,815,449 bp
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• phosphatidylinositol-4,5-bisphosphate binding ; • phosphatidylserine binding ; • GO:0001948 protein binding ; • phosphatidylinositol binding ; • identical protein binding ; • phospholipid binding ; • microtubule binding ; • cytoskeletal protein binding ; • tubulin binding ;
Cellular component	• cell membrane ; • clathrin-coated pit ; • membrane ; • clathrin-coated vesicle ; • cytosol ; • presynaptic endocytic zone membrane ; • cytoplasm ; • cytoskeleton ; • AP-2 adaptor complex ;
Biological process	• membrane invagination ; • protein localization to plasma membrane ; • endocytosis ; • clathrin coat assembly ; • synaptic vesicle endocytosis ; • membrane organization ; • clathrin-dependent endocytosis ; • plasma membrane tubulation ;
	Sources:Amigo / QuickGO
Orthologs
	115548
	218503
	ENSG00000157107
	ENSMUSG00000041685
	Q0JRZ9
	Q3UQN2
	NM_138782 ; NM_001146032
	NM_172591
	NP_001139504 ; NP_620137
	NP_766179
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 15, 2020

FCH domain only protein 2 is a protein that in humans is encoded by the FCHO2 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000157107 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041685 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Katoh M, Katoh M (Aug 2004). "Identification and characterization of human FCHO2 and mouse Fcho2 genes in silico". International Journal of Molecular Medicine. 14 (2): 327–31. doi:10.3892/ijmm.14.2.327. PMID 15254787.
↑ "Entrez Gene: FCHO2 FCH domain only 2".

Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415-8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (Oct 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Henne WM, Kent HM, Ford MG, Hegde BG, Daumke O, Butler PJ, Mittal R, Langen R, Evans PR, McMahon HT (Jul 2007). "Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvature". Structure. 15 (7): 839–52. doi:10.1016/j.str.2007.05.002. PMID 17540576.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000157107 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041685 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15254787-5] Katoh M, Katoh M (Aug 2004). "Identification and characterization of human FCHO2 and mouse Fcho2 genes in silico". International Journal of Molecular Medicine. 14 (2): 327–31. doi:10.3892/ijmm.14.2.327. PMID 15254787.

[entrez-6] "Entrez Gene: FCHO2 FCH domain only 2".

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FCHO2

Related Research Articles

References

Further reading