FCHSD1

FCHSD1
Identifiers
Aliases	FCHSD1 , NWK2, FCH and double SH3 domains 1
External IDs	OMIM: 617555; MGI: 2441771; HomoloGene: 14127; GeneCards: FCHSD1; OMA:FCHSD1 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) [1] Band 5q31.3 Start 141,639,302 bp [1] End 141,651,418 bp [1]
Gene location (Mouse) Chr. Chromosome 18 (mouse) [2] Band 18|18 B3 Start 38,090,484 bp [2] End 38,102,827 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte left ovary Descending thoracic aorta appendix right ovary anterior pituitary ascending aorta sural nerve body of uterus ectocervix Top expressed in granulocyte lip ventricular zone right kidney blood dentate gyrus of hippocampal formation granule cell embryo esophagus neural layer of retina primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function lipid binding Cellular component neuromuscular junction recycling endosome cuticular plate cytoplasm cytoplasmic vesicle cell projection perikaryon Biological process neuromuscular synaptic transmission regulation of actin filament polymerization positive regulation of actin filament polymerization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 89848 319262 Ensembl ENSG00000197948 ENSMUSG00000038524 UniProt Q86WN1 Q6PFY1 RefSeq (mRNA) NM_033449 NM_175684 RefSeq (protein) NP_258260 NP_783615 Location (UCSC) Chr 5: 141.64 – 141.65 Mb Chr 18: 38.09 – 38.1 Mb PubMed search [3] [4]
Wikidata
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FCH and double SH3 domains protein 1 is a protein that in humans is encoded by the FCHSD1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000197948 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038524 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O (Feb 2001). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi: 10.1093/dnares/7.6.357 . PMID   11214971.
6. Katoh M, Katoh M (Apr 2004). "Identification and characterization of human FCHSD1 and FCHSD2 genes in silico". Int J Mol Med. 13 (5): 749–54. doi:10.3892/ijmm.13.5.749. PMID   15067381.
7. "Entrez Gene: FCHSD1 FCH and double SH3 domains 1".

Further reading

• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi: 10.1038/nature03466 . PMID   15815621.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Coyle IP, Koh YH, Lee WC, et al. (2004). "Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila". Neuron. 41 (4): 521–34. doi: 10.1016/S0896-6273(04)00016-9 . PMID   14980202. S2CID   797812.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.