FCHSD1

FCHSD1
Identifiers
Aliases	FCHSD1 , NWK2, FCH and double SH3 domains 1
External IDs	OMIM: 617555 MGI: 2441771 HomoloGene: 14127 GeneCards: FCHSD1
Gene location (Human) Chr. Chromosome 5 (human) [1] Band 5q31.3 Start 141,639,302 bp [1] End 141,651,418 bp [1]
Gene location (Mouse) Chr. Chromosome 18 (mouse) [2] Band 18|18 B3 Start 37,957,431 bp [2] End 37,969,774 bp [2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • lipid binding Cellular component • neuromuscular junction • recycling endosome • cuticular plate • cytoplasm • cytoplasmic vesicle • cell projection • perikaryon Biological process • neuromuscular synaptic transmission • regulation of actin filament polymerization • positive regulation of actin filament polymerization • multi-organism membrane organization Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	89848	319262
Ensembl	ENSG00000197948	ENSMUSG00000038524
UniProt	Q86WN1	Q6PFY1
RefSeq (mRNA)	NM_033449	NM_175684
RefSeq (protein)	NP_258260	NP_783615
Location (UCSC)	Chr 5: 141.64 – 141.65 Mb	Chr 18: 37.96 – 37.97 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

FCH and double SH3 domains protein 1 is a protein that in humans is encoded by the FCHSD1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000197948 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038524 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O (Feb 2001). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi: 10.1093/dnares/7.6.357 . PMID   11214971.
6. Katoh M, Katoh M (Apr 2004). "Identification and characterization of human FCHSD1 and FCHSD2 genes in silico". Int J Mol Med. 13 (5): 749–54. doi:10.3892/ijmm.13.5.749. PMID   15067381.
7. "Entrez Gene: FCHSD1 FCH and double SH3 domains 1".

Further reading

• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi: 10.1038/nature03466 . PMID   15815621.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Coyle IP, Koh YH, Lee WC, et al. (2004). "Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila". Neuron. 41 (4): 521–34. doi:10.1016/S0896-6273(04)00016-9. PMID   14980202. S2CID   797812.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC   139241 . PMID   12477932.