FCRL1

FCRL1
Identifiers
Aliases	FCRL1 , CD307a, FCRH1, IFGP1, IRTA5, Fc receptor like 1
External IDs	OMIM: 606508; MGI: 2442862; HomoloGene: 50472; GeneCards: FCRL1; OMA:FCRL1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q23.1 Start 157,794,403 bp [1] End 157,820,120 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 F1 Start 87,283,694 bp [2] End 87,310,241 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in appendix spleen lymph node granulocyte buccal mucosa cell bone marrow cells blood epithelium of nasopharynx mucosa of ileum tonsil Top expressed in spleen mesenteric lymph nodes blood granulocyte subcutaneous adipose tissue embryo bone marrow thymus Paneth cell yolk sac More reference expression data BioGPS n/a
Gene ontology Molecular function coreceptor activity Cellular component membrane integral component of membrane plasma membrane cell surface Biological process signal transduction B cell activation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 115350 229499 Ensembl ENSG00000163534 ENSMUSG00000059994 UniProt Q96LA6 Q8R4Y0 RefSeq (mRNA) NM_001159397 NM_001159398 NM_052938 NM_001136236 NM_153090 NM_178165 NM_001310545 RefSeq (protein) NP_001152869 NP_001152870 NP_443170 NP_001129708 NP_001297474 NP_694730 NP_835459 Location (UCSC) Chr 1: 157.79 – 157.82 Mb Chr 3: 87.28 – 87.31 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Fc receptor-like protein 1 is a protein that in humans is encoded by the FCRL1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000163534 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059994 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Davis RS, Wang YH, Kubagawa H, Cooper MD (Aug 2001). "Identification of a family of Fc receptor homologs with preferential B cell expression". Proc Natl Acad Sci U S A. 98 (17): 9772–9777. Bibcode:2001PNAS...98.9772D. doi: 10.1073/pnas.171308498 . PMC   55528 . PMID   11493702.
6. Miller I, Hatzivassiliou G, Cattoretti G, Mendelsohn C, Dalla-Favera R (Apr 2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells". Blood. 99 (8): 2662–2669. doi: 10.1182/blood.V99.8.2662 . PMID   11929751.
7. "Entrez Gene: FCRL1 Fc receptor-like 1".

Further reading

• Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). "The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL". Immunogenetics. 59 (4): 323–328. doi:10.1007/s00251-007-0195-9. PMID   17273841. S2CID   1971426.
• Leu CM, Davis RS, Gartland LA, et al. (2005). "FcRH1: an activation coreceptor on human B cells". Blood. 105 (3): 1121–1126. doi: 10.1182/blood-2004-06-2344 . PMID   15479727.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Guselnikov SV, Ershova SA, Mechetina LV, et al. (2002). "A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1". Immunogenetics. 54 (2): 87–95. doi:10.1007/s00251-002-0436-x. PMID   12037601. S2CID   9452957.