FCRL1

FCRL1
Identifiers
Aliases	FCRL1 , CD307a, FCRH1, IFGP1, IRTA5, Fc receptor like 1
External IDs	OMIM: 606508 MGI: 2442862 HomoloGene: 50472 GeneCards: FCRL1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	157,820,120 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	87,310,241 bp
RNA expression pattern
	Top expressed in
	appendix; ; spleen; ; lymph node; ; bone marrow cells; ; blood; ; thymus; ; superficial temporal artery; ; monocyte; ; cancellous bone; ; rectum;
	Top expressed in
	spleen; ; blood; ; subcutaneous adipose tissue; ; bone marrow; ; thymus; ; Paneth cell; ; yolk sac; ; white adipose tissue; ; calvaria; ; right lung lobe;
	More reference expression data
	n/a
Gene ontology
Molecular function	coreceptor activity ;
Cellular component	membrane ; integral component of membrane ; plasma membrane ; cell surface ;
Biological process	signal transduction ; B cell activation ;
	Sources:Amigo / QuickGO
Orthologs
	115350
	229499
	ENSG00000163534
	ENSMUSG00000059994
	Q96LA6
	Q8R4Y0
	NM_001159397 ; NM_001159398 ; NM_052938
	NM_001136236 ; NM_153090 ; NM_178165 ; NM_001310545
	NP_001152869 ; NP_001152870 ; NP_443170
	NP_001129708 ; NP_001297474 ; NP_694730 ; NP_835459
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 12, 2022

Fc receptor-like protein 1 is a protein that in humans is encoded by the FCRL1 gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000163534 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059994 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Davis RS, Wang YH, Kubagawa H, Cooper MD (Aug 2001). "Identification of a family of Fc receptor homologs with preferential B cell expression". Proc Natl Acad Sci U S A. 98 (17): 9772–9777. Bibcode:2001PNAS...98.9772D. doi: 10.1073/pnas.171308498 . PMC 55528 . PMID 11493702.
↑ Miller I, Hatzivassiliou G, Cattoretti G, Mendelsohn C, Dalla-Favera R (Apr 2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells". Blood. 99 (8): 2662–2669. doi: 10.1182/blood.V99.8.2662 . PMID 11929751.
↑ "Entrez Gene: FCRL1 Fc receptor-like 1".

Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). "The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL". Immunogenetics. 59 (4): 323–328. doi:10.1007/s00251-007-0195-9. PMID 17273841. S2CID 1971426.
Leu CM, Davis RS, Gartland LA, et al. (2005). "FcRH1: an activation coreceptor on human B cells". Blood. 105 (3): 1121–1126. doi: 10.1182/blood-2004-06-2344 . PMID 15479727.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Guselnikov SV, Ershova SA, Mechetina LV, et al. (2002). "A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1". Immunogenetics. 54 (2): 87–95. doi:10.1007/s00251-002-0436-x. PMID 12037601. S2CID 9452957.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000163534 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059994 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11493702-5] Davis RS, Wang YH, Kubagawa H, Cooper MD (Aug 2001). "Identification of a family of Fc receptor homologs with preferential B cell expression". Proc Natl Acad Sci U S A. 98 (17): 9772–9777. Bibcode:2001PNAS...98.9772D. doi: 10.1073/pnas.171308498 . PMC 55528 . PMID 11493702.

[pmid11929751-6] Miller I, Hatzivassiliou G, Cattoretti G, Mendelsohn C, Dalla-Favera R (Apr 2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells". Blood. 99 (8): 2662–2669. doi: 10.1182/blood.V99.8.2662 . PMID 11929751.

[entrez-7] "Entrez Gene: FCRL1 Fc receptor-like 1".

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FCRL1

Related Research Articles

References

Further reading