FLVCR1

Last updated
FLVCR1
Identifiers
Aliases FLVCR1 , AXPC1, FLVCR, MFSD7B, PCA, PCARP, feline leukemia virus subgroup C cellular receptor 1, SLC49A1, FLVCR heme transporter 1
External IDs OMIM: 609144 MGI: 2444881 HomoloGene: 56661 GeneCards: FLVCR1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014053

NM_001081259
NM_001313747
NM_198025

RefSeq (protein)

NP_054772

NP_001074728
NP_001300676
NP_932142

Location (UCSC) Chr 1: 212.86 – 212.9 Mb Chr 1: 191.01 – 191.03 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Feline leukemia virus subgroup C receptor-related protein 1 is a protein that in humans is encoded by the FLVCR1 gene (SLC49A1). [5] [6] [7] [8]

Related Research Articles

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<i>Feline leukemia virus</i> Species of virus

Feline leukemia virus (FeLV) is a retrovirus that infects cats. FeLV can be transmitted from infected cats when the transfer of saliva or nasal secretions is involved. If not defeated by the animal's immune system, the virus weakens the cat's immune system which can lead to diseases which can be lethal. Because FeLV is cat-to-cat contagious, FeLV+ cats should only live with other FeLV+ cats.

The murine leukemia viruses are retroviruses named for their ability to cause cancer in murine (mouse) hosts. Some MLVs may infect other vertebrates. MLVs include both exogenous and endogenous viruses. Replicating MLVs have a positive sense, single-stranded RNA (ssRNA) genome that replicates through a DNA intermediate via the process of reverse transcription.

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Poliovirus receptor-related 2

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GPR183

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MX1

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Thrombopoietin receptor

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PRKD3

Serine/threonine-protein kinase D3 (PKD3) or PKC-nu is an enzyme that in humans is encoded by the PRKD3 gene.

TAF10

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SLC20A1

Sodium-dependent phosphate transporter 1 is a protein that in humans is encoded by the SLC20A1 gene.

KAT6A

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SLC20A2

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EIF3M

Eukaryotic translation initiation factor 3, subunit M (eIF3m) also known as PCI domain containing 1 (PCID1), is a protein that in humans is encoded by the EIF3M gene.

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000162769 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000066595 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Tailor CS, Willett BJ, Kabat D (1999). "A putative cell surface receptor for anemia-inducing feline leukemia virus subgroup C is a member of a transporter superfamily". J. Virol. 73 (8): 6500–5. doi:10.1128/JVI.73.8.6500-6505.1999. PMC   112732 . PMID   10400745.
  6. Quigley JG, Burns CC, Anderson MM, Lynch ED, Sabo KM, Overbaugh J, Abkowitz JL (2000). "Cloning of the cellular receptor for feline leukemia virus subgroup C (FeLV-C), a retrovirus that induces red cell aplasia". Blood. 95 (3): 1093–9. doi:10.1182/blood.V95.3.1093.003k01_1093_1099. PMID   10648427.
  7. "Entrez Gene: FLVCR feline leukemia virus subgroup C cellular receptor".
  8. Crielaard, Bart J.; Lammers, Twan; Rivella, Stefano (2017-02-03). "Targeting iron metabolism in drug discovery and delivery". Nature Reviews Drug Discovery. advance online publication (6): 400–423. doi:10.1038/nrd.2016.248. ISSN   1474-1784. PMC   5455971 . PMID   28154410.

Further reading