| LRATD2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | LRATD2 , BCMP101, NSE2, family with sequence similarity 84 member B, FAM84B, LRAT domain containing 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 609483 MGI: 3026924 HomoloGene: 18379 GeneCards: LRATD2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Family with sequence similarity 84 member B is a protein that in humans is encoded by the FAM84B gene. [5]
Kruppel-like factor 4 is a member of the KLF family of zinc finger transcription factors, which belongs to the relatively large family of SP1-like transcription factors. KLF4 is involved in the regulation of proliferation, differentiation, apoptosis and somatic cell reprogramming. Evidence also suggests that KLF4 is a tumor suppressor in certain cancers, including colorectal cancer. It has three C2H2-zinc fingers at its carboxyl terminus that are closely related to another KLF, KLF2. It has two nuclear localization sequences that signals it to localize to the nucleus. In embryonic stem cells (ESCs), KLF4 has been demonstrated to be a good indicator of stem-like capacity. It is suggested that the same is true in mesenchymal stem cells (MSCs).
Growth arrest and DNA-damage-inducible protein GADD45 gamma is a protein that in humans is encoded by the GADD45G gene on chromosome 9. GADD45G is also known as CR6, DDIT2, GRP17, OIG37, and GADD45gamma. GADD45G is involved in several different processes, including sexual development, human-specific brain development, tumor suppression, and the cellular stress response. GADD45G interacts with several other proteins that are involved in DNA repair, cell cycle control, apoptosis, and senescence. Low expression of GADD45G has been associated with many types of cancer.
Serine/threonine-protein kinase PAK 5 is an enzyme that in humans is encoded by the PAK5 gene.
Telomerase protein component 1 is an enzyme that in humans is encoded by the TEP1 gene.
Serine/threonine-protein kinase PAK 6 is an enzyme that in humans is encoded by the PAK6 gene.
Deleted in esophageal cancer 1 is a protein that in humans is encoded by the DEC1 gene.
Solute carrier family 52, member 3, formerly known as chromosome 20 open reading frame 54 and riboflavin transporter 2, is a protein that in humans is encoded by the SLC52A3 gene.
S100 calcium binding protein A14 (S100A14) is a protein that in humans is encoded by the S100A14 gene.
Eva-1 homolog A is a protein that in humans is encoded by the EVA1A gene.
Cytoskeleton regulator RNA is a long non-coding RNA that in humans is encoded by the CYTOR gene.
Dishevelled binding antagonist of beta catenin 2 is a protein that in humans is encoded by the DACT2 gene.
Sushi domain containing 2 is a protein that in humans is encoded by the SUSD2 gene.
MicroRNA 106a is a microRNA that in humans is encoded by the MIR106A gene.
CKLF-like MARVEL transmembrane domain-containing protein 3, also termed chemokine-like factor superfamily 3, is a member of the CKLF-like MARVEL transmembrane domain-containing family of proteins. In humans, CMTM2 protein is encoded by the CMTM3 gene located in band 22.1 on the long arm of chromosome 16. This protein is expressed in a wide range of tissues, including fetal tissues. It is highly expressed in the male reproductive system, particularly testicular tissues and may play a role in the development of this tissue. It is also highly expressed in the immune system including circulating blood cells, i.e. B lymphocytes, CD4+ T lymphocytes, and monocytes. However, CMTM3 protein is weakly expressed or unexpressed in the malignant tissues of several types of cancers. In many but not all of theses cancers, this decreased or lack of expression appears due to methylation of the GpC islands in the promoter region, and thereby the silencing, of the CMTM3 gene.
MicroRNA 141 is a non-coding RNA molecule that in humans is encoded by the MIR141 gene.
Deleted in lung and esophageal cancer 1 is a protein that in humans is encoded by the DLEC1 gene.
Ras association domain family member 10 is a protein that in humans is encoded by the RASSF10 gene.
Augurin is a protein that in humans is encoded by the C2orf40 gene.
Nabil F. Saba is an American oncologist. He is currently Professor and Vice-chair of Hematology and Medical Oncology, and Professor of Otolaryngology at the Winship Cancer Institute at the Emory University School of Medicine in Atlanta, Georgia. He is a specialist in the field of head and neck oncology. Saba has authored more than 200 peer-reviewed articles. He is the inaugural Lynne and Howard Halpern Chair in Head and Neck Cancer Research.
MIR22HG, also known as C17orf91, MGC14376, MIRN22, hsa-mir-22, and miR-22 is a human gene that encodes a noncoding RNA (ncRNA).This RNA molecule is not translated into a protein but nonetheless may have important functions.
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