Family with sequence similarity 84 member b

LRATD2
Identifiers
Aliases	LRATD2 , BCMP101, NSE2, family with sequence similarity 84 member B, FAM84B, LRAT domain containing 2
External IDs	OMIM: 609483; MGI: 3026924; HomoloGene: 18379; GeneCards: LRATD2; OMA:LRATD2 - orthologs
Gene location (Human) Chr. Chromosome 8 (human) [1] Band 8q24.21 Start 126,552,443 bp [1] End 126,558,478 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 D1 Start 60,690,843 bp [2] End 60,725,627 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in parotid gland retinal pigment epithelium secondary oocyte ventricular zone renal medulla palpebral conjunctiva skin of arm pancreatic epithelial cell oral cavity buccal mucosa cell Top expressed in lobe of prostate migratory enteric neural crest cell lacrimal gland right lung lobe Paneth cell secondary oocyte retinal pigment epithelium stria vascularis ileum left lung lobe More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 157638 399603 Ensembl ENSG00000168672 ENSMUSG00000072568 UniProt Q96KN1 D3YXJ5 RefSeq (mRNA) NM_174911 NM_001162926 NM_207269 RefSeq (protein) NP_777571 NP_001156398 Location (UCSC) Chr 8: 126.55 – 126.56 Mb Chr 15: 60.69 – 60.73 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Family with sequence similarity 84 member B is a protein that in humans is encoded by the FAM84B gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000168672 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000072568 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Family with sequence similarity 84 member B" . Retrieved 2018-05-27.

Further reading

• Pomerantz MM, Beckwith CA, Regan MM, Wyman SK, Petrovics G, Chen Y, Hawksworth DJ, Schumacher FR, Mucci L, Penney KL, Stampfer MJ, Chan JA, Ardlie KG, Fritz BR, Parkin RK, Lin DW, Dyke M, Herman P, Lee S, Oh WK, Kantoff PW, Tewari M, McLeod DG, Srivastava S, Freedman ML (July 2009). "Evaluation of the 8q24 prostate cancer risk locus and MYC expression". Cancer Res. 69 (13): 5568–74. doi:10.1158/0008-5472.CAN-09-0387. PMC   2884104 . PMID   19549893.
• White KL, Sellers TA, Fridley BL, Vierkant RA, Phelan CM, Tsai YY, Kalli KR, Berchuck A, Iversen ES, Hartmann LC, Liebow M, Armasu S, Fredericksen Z, Larson MC, Duggan D, Couch FJ, Schildkraut JM, Cunningham JM, Goode EL (February 2010). "Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer". Twin Res Hum Genet. 13 (1): 43–56. doi:10.1375/twin.13.1.43. PMC   2932441 . PMID   20158306.
• Hsu FM, Cheng JC, Chang YL, Lee JM, Koong AC, Chuang EY (May 2015). "Circulating mRNA Profiling in Esophageal Squamous Cell Carcinoma Identifies FAM84B As A Biomarker In Predicting Pathological Response to Neoadjuvant Chemoradiation". Sci Rep. 5 10291. Bibcode:2015NatSR...510291H. doi:10.1038/srep10291. PMC   4434848 . PMID   25980316.
• Cheng C, Cui H, Zhang L, Jia Z, Song B, Wang F, Li Y, Liu J, Kong P, Shi R, Bi Y, Yang B, Wang J, Zhao Z, Zhang Y, Hu X, Yang J, He C, Zhao Z, Wang J, Xi Y, Xu E, Li G, Guo S, Chen Y, Yang X, Chen X, Liang J, Guo J, Cheng X, Wang C, Zhan Q, Cui Y (2016). "Genomic analyses reveal FAM84B and the NOTCH pathway are associated with the progression of esophageal squamous cell carcinoma". GigaScience. 5: 1. doi: 10.1186/s13742-015-0107-0 . PMC   4709967 . PMID   26759717.