Flavin adenine dinucleotide synthetase 1

FLAD1
Identifiers
Aliases	FLAD1 , FAD1, FADS, PP591, flavin adenine dinucleotide synthetase 1, LSMFLAD
External IDs	OMIM: 610595 MGI: 2443030 HomoloGene: 115598 GeneCards: FLAD1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	154,993,111 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	89,411,870 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; gastrocnemius muscle; ; right lobe of thyroid gland; ; right lobe of liver; ; ganglionic eminence; ; body of stomach; ; left lobe of thyroid gland; ; left ventricle; ; spleen; ; right uterine tube;
	Top expressed in
	interventricular septum; ; extraocular muscle; ; left lobe of liver; ; digastric muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; triceps brachii muscle; ; right ventricle; ; brown adipose tissue; ; myocardium of ventricle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity ; nucleotide binding ; nucleotidyltransferase activity ; protein binding ; catalytic activity ; ATP binding ; FMN adenylyltransferase activity ;
Cellular component	mitochondrial matrix ; plasma membrane ; mitochondrion ; cytoplasm ; cytosol ;
Biological process	riboflavin metabolic process ; metabolism ; FAD biosynthetic process ;
	Sources:Amigo / QuickGO
Orthologs
	80308
	319945
	ENSG00000160688
	ENSMUSG00000042642
	Q8NFF5
	Q8R123
	NM_001184891 ; NM_001184892 ; NM_025207 ; NM_201398
	NM_177041
	NP_001171820 ; NP_001171821 ; NP_079483 ; NP_958800
	NP_796015 ; NP_001349304 ; NP_001349305
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 10, 2022

Flavin adenine dinucleotide synthetase 1 is a protein that in humans is encoded by the FLAD1 gene. ^[5]

Function

This gene encodes the enzyme that catalyzes adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000160688 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042642 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Flavin adenine dinucleotide synthetase 1" . Retrieved 2016-03-04.

Flavin adenine dinucleotide synthetase 1

Contents

Function

Related Research Articles

References

Further reading