Fred Huffman Wilt

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Fred Huffman Wilt is an American biologist [1] who was elected a Fellow of the American Association for the Advancement of Science. His research currently includes the endoskeletal spicule of sea urchin embryos, and its biomineralization relative to its cellular and molecular foundation. [2] [3] [4]

Selected publications

Related Research Articles

Sea urchin Class of echinoderms

Sea urchins, are typically spiny, globular animals, echinoderms in the class Echinoidea. About 950 species live on the seabed, inhabiting all oceans and depth zones from the intertidal to 5,000 metres. Their hard shells (tests) are round and spiny, usually from 3 to 10 cm across. Sea urchins move slowly, crawling with their tube feet, and sometimes pushing themselves with their spines. They feed primarily on algae but also eat slow-moving or sessile animals. Their predators include sea otters, starfish, wolf eels, triggerfish, and humans.

Gastrulation Stage in embryonic development in which germ layers form

In developmental biology, gastrulation is a phase early in the embryonic development of most animals, during which the blastula is reorganized into a multilayered structure known as the gastrula. Before gastrulation, the embryo is a continuous epithelial sheet of cells; by the end of gastrulation, the embryo has begun differentiation to establish distinct cell lineages, set up the basic axes of the body, and internalized one or more cell types including the prospective gut.

Eric Harris Davidson was an American developmental biologist at the California Institute of Technology. Davidson was best known for his pioneering work on the role of gene regulation in evolution, on embryonic specification and for spearheading the effort to sequence the genome of the purple sea urchin, Strongylocentrotus purpuratus. He devoted a large part of his professional career to developing an understanding of embryogenesis at the genetic level. He wrote many academic works describing his work, including a textbook on early animal development.

<i>Strongylocentrotus purpuratus</i> Species of sea urchin

The purple sea urchin, Strongylocentrotus purpuratus, lives along the eastern edge of the Pacific Ocean extending from Ensenada, Mexico, to British Columbia, Canada. This sea urchin species is deep purple in color, and lives in lower inter-tidal and nearshore sub-tidal communities. Its eggs are orange when secreted in water. January, February, and March function as the typical active reproductive months for the species. Sexual maturity is reached around two years.

FSCN1

Fascin is a protein that in humans is encoded by the FSCN1 gene.

HOXD9

Homeobox protein Hox-D9 is a protein that in humans is encoded by the HOXD9 gene.

<i>CSDA</i> (gene)

DNA-binding protein A is a protein that in humans is encoded by the CSDA gene.

NODAL

Nodal is a secretory protein that in humans is encoded by the NODAL gene which is located on chromosome 10q22.1. It belongs to the transforming growth factor beta (TGF-β) superfamily. Like many other members of this superfamily it is involved in cell differentiation in early embryogenesis, playing a key role in signal transfer from the node, in the anterior primitive streak, to lateral plate mesoderm (LPM).

DLX2

Homeobox protein DLX-2 is a protein that in humans is encoded by the DLX2 gene.

Gretchen Hofmann is professor of ecological physiology of marine organisms at the University of California, Santa Barbara. She holds a B.S. from the University of Wyoming, and an M.S. and Ph.D. from the University of Colorado at Boulder in Environmental, Population and Organismal Biology.

MCOLN3

Mucolipin-3 also known as TRPML3 is a protein that in humans is encoded by the MCOLN3 gene. It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.

<i>Eucidaris tribuloides</i> Species of echinoderm

Eucidaris tribuloides, the slate pencil urchin, is a species of cidaroid sea urchins that inhabits littoral regions of the Atlantic Ocean. As a member of the basal echinoid order Cidaroida, its morphological, developmental and molecular genetic characteristics make it a phylogenetically interesting species.

BioTapestry is an open source software application for modeling and visualizing gene regulatory networks (GRNs).

Skeletogenesis is a key morphogenetic event in the embryonic development of vertebrates and is of equal, although transient, importance in the development of the sea urchin, a marine invertebrate. The larval sea urchin does not resemble its adult form, because the sea urchin is an indirect developer, meaning its larva form must undergo metamorphosis to form the juvenile adult. Here, the focus is on skeletogenesis in the sea urchin species Strongylocentrotus purpuratus, as this species has been most thoroughly studied and characterized.

Donal Thomas Manahan is an Irish-born American marine scientist and comparative physiologist. He is known for Antarctic and deep oceanic research on the physiology and ecology of marine invertebrates and their larvae in extreme environments, and for his interest in the role of dissolved organic material as a larval food source.

Amorphous calcium carbonate

Amorphous calcium carbonate (ACC) is the amorphous and least stable polymorph of calcium carbonate. ACC is extremely unstable under normal conditions and is found naturally in taxa as wide-ranging as sea urchins, corals, mollusks, and foraminifera. It is usually found as a monohydrate, holding the chemical formula CaCO3·H2O; however, it can also exist in a dehydrated state, CaCO3. ACC has been known to science for over 100 years when a non-diffraction pattern of calcium carbonate was discovered by Sturcke Herman, exhibiting its poorly-ordered nature.

Envelysin is an enzyme. This enzyme catalyses the following chemical reaction

Pupa Gilbert Italian-American biophysicist and geobiologist

Pupa Gilbert is an American biophysicist and geobiologist. She has been pioneering synchrotron spectromicroscopy methods since 1989, and she continues to use and develop them today. Since 2004 she has focused on biomineralization in sea urchins, mollusk shells, and tunicates. She and her group are frequent users of the Berkeley-Advanced Light Source.

Mosaic protein

A mosaic protein is a protein that is made up of different protein domains, giving the protein multiple functions. These proteins have quaternary structures, as they are made up of multiple tertiary structured protein domains. Protein domains can combine to form different types of proteins, creating a diversity of proteins. These domains are spread throughout the genome because they are mobile, which is why some domains can be found in a variety of proteins, even though they are seemingly unrelated. This also allows the domains to fold independently, and so they don't become deformed and unfolded in a new environment.

Echinobase

Echinobase is a web information system that catalogs diverse genomic and biological data for the echinoderm clade. The system provides a gene search engine, genomics browser and other bioinformatics tools to explore genomic and transcriptomic data. The Echinobase information system focuses on information from eight echinoderm research models: Strongylocentrotus purpuratus, Strongylocentrotus fransciscanus, Allocentrotus fragilis, Lytechinus variegatus, Patiria miniata, Parastichopus parvimensis and Ophiothrix spiculata, Eucidaris tribuloides. The goal of Echinobase is to support molecular biological science including developmental processes and gene regulatory networks.

References

  1. "Fred Huffman Wilt". scholar.google.com. Retrieved June 3, 2017.CS1 maint: discouraged parameter (link)
  2. "Fred Huffman Wilt". aaas.org. Retrieved April 26, 2017.CS1 maint: discouraged parameter (link)
  3. "Fellow". gf.org. Retrieved April 26, 2017.CS1 maint: discouraged parameter (link)
  4. "Fred Huffman Wilt". berkeley.edu. Retrieved April 26, 2017.CS1 maint: discouraged parameter (link)