Frederick Alt | |
---|---|
Other names | Fred Alt |
Education | |
Children | J. Kenji López-Alt |
Scientific career | |
Institutions | |
Doctoral advisor | Robert Schimke |
Other academic advisors | David Baltimore |
Doctoral students | Karen M. Frank |
Frederick W. Alt is an American geneticist. He is a member of the immunology section of the National Academy of Sciences and a Charles A. Janeway Professor of Pediatrics, and Professor of Genetics at Harvard Medical School. [1] He is the Director of the Program in Cellular and Molecular Medicine at the Boston Children's Hospital. [2] He is a Howard Hughes Medical Institute investigator, since 1987.
Alt completed his undergraduate studies at Brandeis University, graduating in 1971. [3] He then went on to earn a Ph.D. in Biology from Stanford University in 1977 while under the research direction of Robert Schimke. He performed his postdoctoral work in David Baltimore's laboratory at Massachusetts Institute of Technology (MIT). [4] From 1982 to 1991 he was on the faculty at Columbia University and then moved to Harvard Medical School. [5]
Alt's research interest is in maintenance of genome stability in cells of the mammalian immunological system, particularly antigen receptor variable region gene assembly in developing B and T lymphocytes, immunoglobulin heavy chain class switch recombination (CSR), and somatic hypermutation in activated mature B lymphocytes. [1]
Alt is the son-in-law of organic chemist Koji Nakanishi, former Centennial Professor of Chemistry and chair of the Chemistry Department at Columbia University. [6]
Alt is also the father of the chef and food writer J. Kenji López-Alt. [7]
He has received many awards, this is a select list:
The Cancer Research Institute of New York gives an annual prize in his honor, the Frederick W. Alt Award for New Discoveries in Immunology.
Alt is a member of:
His father, Frederick Alt, is a professor at Harvard Medical School