Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals and chain reactions that may damage the cells of organisms. Antioxidants such as thiols or ascorbic acid may act to inhibit these reactions. To balance oxidative stress, plants and animals maintain complex systems of overlapping antioxidants, such as glutathione.
Proceedings of the Royal Society is the parent title of two scientific journals published by the Royal Society. Originally a single journal, it was split into two separate journals in 1905:
Lipid peroxidation is the chain of reactions of oxidative degradation of lipids. It is the process in which free radicals "steal" electrons from the lipids in cell membranes, resulting in cell damage. This process proceeds by a free radical chain reaction mechanism. It most often affects polyunsaturated fatty acids, because they contain multiple double bonds in between which lie methylene bridges (-CH2-) that possess especially reactive hydrogen atoms. As with any radical reaction, the reaction consists of three major steps: initiation, propagation, and termination. The chemical products of this oxidation are known as lipid peroxides or lipid oxidation products (LOPs).
The oxoglutarate dehydrogenase complex (OGDC) or α-ketoglutarate dehydrogenase complex is an enzyme complex, most commonly known for its role in the citric acid cycle.
Fenton's reagent is a solution of hydrogen peroxide (H2O2) with ferrous iron (typically iron(II) sulfate, FeSO4) as a catalyst that is used to oxidize contaminants or waste waters. Fenton's reagent can be used to destroy organic compounds such as trichloroethylene (TCE) and tetrachloroethylene (perchloroethylene, PCE). It was developed in the 1890s by Henry John Horstman Fenton as an analytical reagent.
The American Journal of Public Health is a monthly peer-reviewed public health journal published by the American Public Health Association that covers health policy and public health. The journal was established in 1911 and its stated mission is "to advance public health research, policy, practice, and education." The journal occasionally publishes themed supplements. The editor-in-chief is Alfredo Morabia.
Physics in Medicine & Biology is a biweekly peer-reviewed medical journal covering research on the application of physics to medicine, physiology, and biology. It was established in 1956 and is published by IOP Publishing on behalf of the Institute of Physics and Engineering in Medicine. It is also an official journal of the following medical societies: Canadian Organization of Medical Physics, Deutsche Gesellschaft für Medizinische Physik, Japanese Association of Radiological Physics, European Federation of Organisations for Medical Physics, and the International Organization for Medical Physics. The editor-in-chief is Katia Parodi.
Irwin Fridovich was an American biochemist who, together with his graduate student Joe M. McCord, discovered the enzymatic activity of copper-zinc superoxide dismutase (SOD),—to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct of normal oxygen metabolism. Subsequently, Fridovich's research group also discovered the manganese-containing and the iron-containing SODs from Escherichia coli and the mitochondrial MnSOD (SOD2), now known to be an essential protein in mammals. He spent the rest of his career studying the biochemical mechanisms of SOD and of biological superoxide toxicity, using bacteria as model systems. Fridovich was also Professor Emeritus of Biochemistry at Duke University.
Victor Darley-Usmar is a free-radical biologist and biochemist, the UAB Endowed Professor in Mitochondrial Medicine and Pathology at the University of Alabama at Birmingham. Darley-Usmar also contributed to a book titled Microbes, Bugs & Wonder Drugs, a science book written for young readers and their families.
The Journal of Photochemistry and Photobiology is a series of peer-reviewed scientific journals covering the fields of photochemistry and photobiology, published by Elsevier. It was originally established in 1972, and split into Journal of Photochemistry and Photobiology A: Chemistry and Journal of Photochemistry and Photobiology B: Biology in 1987. A third title; Journal of Photochemistry and Photobiology C: Photochemistry Reviews, was established in 2000 and is the official journal of the Japanese Photochemistry Association.
Journal of Mathematical Biology is a peer-reviewed, mathematics journal, published by Springer Verlag. Founded in 1974, the journal publishes articles on mathematical biology. In particular, papers published in this journal 'should either provide biological insight as a result of mathematical analysis or identify and open up challenging new types of mathematical problems that derive from biological knowledge'. It is the official journal of the European Society for Mathematical and Theoretical Biology. The two editors-in-chief are M. Gyllenberg and M. Lewis.
Matrix Biology is a peer-reviewed scientific journal in the field of matrix biology. The journal is published 8 times per year by Elsevier. The journal was established in 1981 as Collagen and Related Research and renamed to Matrix: Collagen and Related Research in 1988, before obtaining its current name in 1994. It is an official journal of the American Society for Matrix Biology and the International Society for Matrix Biology. The current editor-in-chief is Renato V. Iozzo.
Antioxidants & Redox Signaling is a peer-reviewed scientific journal covering reduction–oxidation (redox) signaling and antioxidant research. It covers topics such as reactive oxygen species/reactive nitrogen species (ROS/RNS) as messengers gaseous signal transducers, hypoxia and tissue oxygenation, microRNA, prokaryotic systems, and lessons from plant biology.
Nuclear Medicine and Biology is a peer-reviewed medical journal published by Elsevier that covers research on all aspects of nuclear medicine, including radiopharmacology, radiopharmacy and clinical studies of targeted radiotracers. It is the official journal of the Society of Radiopharmaceutical Sciences. According to the Journal Citation Reports, the journal has a 2011 impact factor of 3.023.
Henry Jay Forman is both Distinguished Professor Emeritus of Biochemistry at the University of California, Merced. and Research Professor Emeritus of Gerontology at the USC Leonard Davis School of Gerontology. He is a specialist in free radical biology and chemistry, antioxidant defense, and pioneered work in redox signaling including the mechanisms of induced resistance to oxidative stress.
Experimental & Molecular Medicine is a monthly peer-reviewed open access medical journal covering biochemistry and molecular biology. It was established in 1964 as the Korean Journal of Biochemistry or Taehan Saenghwa Hakhoe Chapchi and published bi-annually. It was originally in Korean becoming an English-language journal in 1975. In 1994 the journal began publishing quarterly. It obtained its current name in 1996 at which time it also began publishing bi-monthly, switching to monthly in 2009. It is the official journal of the Korean Society for Medical Biochemistry and Molecular Biology. The editor-in-chief is Dae-Myung Jue. It is published by the Nature Publishing Group. The full text of the journal from 2008 to the present is available at PubMed Central.
Rafael Radi is an Uruguayan biochemist and biomedical scientist that has extensively worked to elucidate molecular mechanisms by which free radicals, oxidants and nitric oxide participate in human pathologies. In particular, he has made relevant contributions to unravel how the signal transducing free radical nitric oxide can evolve into toxic species via the formation of secondary nitric oxide-derived oxidants. His work has characterized reactions of oxidizing species with biological targets, the role of mitochondrial dysfunction is the alterations of cellular redox homeostasis and the impact of these biochemical processes in disease states. He has studied the actions of synthetic compounds in redox-based therapeutics, including in cardiovascular and neurodegenerative diseases. This work has also contributed to understand the redox biology of host cell interactions with intracellular pathogens and the impact in the control of infectious diseases. His seminal paper related to the biochemical actions of peroxynitrite, a potent oxidant and nucleophile formed secondary to the diffusion-controlled reaction of nitric oxide with superoxide radicals together with Joe S. Beckman, Kent Bush and Bruce A. Freeman in 1991 has been selected as a JBC Classics due to its influence in the field.
Barry Halliwell is an English biochemist, chemist and university administrator, specialising in free radical metabolism in both animals and plants. His name is included in the "Foyer–Halliwell–Asada" pathway, a cellular process of hydrogen peroxide metabolism in plants and animals, named for the three principal discoverers, with Christine Foyer and Kozi Asada. He moved to Singapore in 2000, and served as Deputy President of the National University of Singapore (2006–15), where he continues to hold a Tan Chin Tuan Centennial professorship.
Nicola Elizabeth Brasch is a New Zealand chemistry academic. She is currently a full professor at the Auckland University of Technology.
Redox Biology is an open-access peer-reviewed scientific journal and an official journal of the Society for Redox Biology and Medicine and the Society for Free Radical Research-Europe. The journal covers research on redox biology, aging, signaling, biological chemistry and medical implications of free radicals for health and disease. According to the Journal Citation Reports, the journal's 2020 impact factor is 11.799.
