Freeze spray

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Spray containing propane, butane, and ethanol, for dental applications Kaltespray 2009 PD IMG 5196.JPG
Spray containing propane, butane, and ethanol, for dental applications

Freeze spray (cold spray or vapocoolant) is a type of aerosol spray product containing a liquified gas used for rapidly cooling surfaces, in medical and industrial applications. It is usually sold in hand-held spray cans. It may consist of various substances, which produce different temperatures, depending on the application.

Contents

Some of them are highly flammable. [1] Several other types of compressed gas sprays also have a freezing effect: for example, tetrafluoroethane, gas dusters, liquid nitrogen, and carbon dioxide fire extinguishers.

Applications

"Magic" ice spray used to treat a sports injury Other (5071755821).jpg
"Magic" ice spray used to treat a sports injury

Industrial

For spot-cooling of electronic components during troubleshooting, dimethyl ether or tetrafluoroethane may be used. [2]

Freeze sprays are also used to contract metal for assembly or disassembly of interference fit parts.[ citation needed ]

The extreme temperature can cause viscoelastic materials to change to glass phase. Thus it is useful for removing many types of pressure sensitive adhesives. [3]

Medical

Medical cryotherapy gun with liquid nitrogen Cryogun.jpg
Medical cryotherapy gun with liquid nitrogen

In medical applications, spray cans containing dimethyl ether [4] or tetrafluoroethane may also be used to freeze and destroy tissue, for removal of warts and skin tags, or other uses in cryosurgery. Liquified petroleum gas including propane and butane is sometimes used. These all may also be used as a topical anesthetic, due to the numbing effect of cold, though there is risk of frostbite.

Cold sprays are sometimes used to carefully freeze and kill attached ticks, with successful application often resulting in the dead tick falling off. [5]

Chloroethane may be used as a topical pain reliever, and an alternative to ice pack therapy to reduce inflammation and swelling. Since its boiling point is well above the freezing point of water, there is less risk of freezing the skin, though it can still be dangerous if misused. It may be used to treat sports injuries, where it is sometimes known as ice spray or magic spray. [6]

Freeze sprays are also utilized in frozen section biopsies to rapidly cool or freeze small tissue samples at the microtome or cryostat. [7]

Other

Freeze spray has been shown useful for the field marking of animals; for example marking the tails of monkeys. Research is continuing to help control the application dosage and time to minimize permanent damage to the animals. [8]

See also

Related Research Articles

Cryobiology is the branch of biology that studies the effects of low temperatures on living things within Earth's cryosphere or in science. The word cryobiology is derived from the Greek words κρῧος [kryos], "cold", βίος [bios], "life", and λόγος [logos], "word". In practice, cryobiology is the study of biological material or systems at temperatures below normal. Materials or systems studied may include proteins, cells, tissues, organs, or whole organisms. Temperatures may range from moderately hypothermic conditions to cryogenic temperatures.

A propellant is a mass that is expelled or expanded in such a way as to create a thrust or another motive force in accordance with Newton's third law of motion, and "propel" a vehicle, projectile, or fluid payload. In vehicles, the engine that expels the propellant is called a reaction engine. Although technically a propellant is the reaction mass used to create thrust, the term "propellant" is often used to describe a substance which contains both the reaction mass and the fuel that holds the energy used to accelerate the reaction mass. For example, the term "propellant" is often used in chemical rocket design to describe a combined fuel/propellant, although the propellants should not be confused with the fuel that is used by an engine to produce the energy that expels the propellant. Even though the byproducts of substances used as fuel are also often used as a reaction mass to create the thrust, such as with a chemical rocket engine, propellant and fuel are two distinct concepts.

<span class="mw-page-title-main">Ice diving</span> Underwater diving under ice

Ice diving is a type of penetration diving where the dive takes place under ice. Because diving under ice places the diver in an overhead environment typically with only a single entry/exit point, it requires special procedures and equipment. Ice diving is done for purposes of recreation, scientific research, public safety and other professional or commercial reasons.

<span class="mw-page-title-main">Liquid nitrogen</span> Liquid state of nitrogen

Liquid nitrogen (LN2) is nitrogen in a liquid state at low temperature. Liquid nitrogen has a boiling point of about −196 °C (−321 °F; 77 K). It is produced industrially by fractional distillation of liquid air. It is a colorless, mobile liquid whose viscosity is about one-tenth that of acetone (i.e. roughly one-thirtieth that of water at room temperature). Liquid nitrogen is widely used as a coolant.

<span class="mw-page-title-main">Mpemba effect</span> Natural phenomenon that hot water freezes faster than cold

The Mpemba effect is the name given to the observation that a liquid which is initially hot can freeze faster than the same liquid which begins cold, under otherwise similar conditions. There is disagreement about its theoretical basis and the parameters required to produce the effect.

<span class="mw-page-title-main">Dimethyl sulfoxide</span> Organosulfur chemical compound used as a solvent

Dimethyl sulfoxide (DMSO) is an organosulfur compound with the formula (CH3)2SO. This colorless liquid is the sulfoxide most widely used commercially. It is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. It has a relatively high boiling point. DMSO is metabolised to compounds that leave a garlic-like taste in the mouth after DMSO is absorbed by skin.

Dimethyl ether (DME; also known as methoxymethane) is the organic compound with the formula CH3OCH3, (sometimes ambiguously simplified to C2H6O as it is an isomer of ethanol). The simplest ether, it is a colorless gas that is a useful precursor to other organic compounds and an aerosol propellant that is currently being demonstrated for use in a variety of fuel applications.

<span class="mw-page-title-main">Aerosol spray dispenser</span> Dispensing system of an aerosol mist

Aerosol spray is a type of dispensing system which creates an aerosol mist of liquid particles. It comprises a can or bottle that contains a payload, and a propellant under pressure. When the container's valve is opened, the payload is forced out of a small opening and emerges as an aerosol or mist.

<span class="mw-page-title-main">Eschar</span> Piece of dead tissue caused by some skin injuries

An eschar is a slough or piece of dead tissue that is cast off from the surface of the skin, particularly after a burn injury, but also seen in gangrene, ulcer, fungal infections, necrotizing spider bite wounds, tick bites associated with spotted fevers and exposure to cutaneous anthrax. The term ‘eschar’ is not interchangeable with ‘scab’. An eschar contains necrotic tissue whereas a scab is composed of dried blood and exudate.

<span class="mw-page-title-main">Cryosurgery</span> Cauterization by freezing tissue

Cryosurgery is the use of extreme cold in surgery to destroy abnormal or diseased tissue; thus, it is the surgical application of cryoablation. Cryosurgery has been historically used to treat a number of diseases and disorders, especially a variety of benign and malignant skin conditions.

Cryotherapy, sometimes known as cold therapy, is the local or general use of low temperatures in medical therapy. Cryotherapy may be used to treat a variety of tissue lesions. The most prominent use of the term refers to the surgical treatment, specifically known as cryosurgery or cryoablation. Cryosurgery is the application of extremely low temperatures to destroy abnormal or diseased tissue and is used most commonly to treat skin conditions.

1,1,1,2-Tetrafluoroethane (also known as norflurane (INN), R-134a, Klea 134a, Freon 134a, Forane 134a, Genetron 134a, Green Gas, Florasol 134a, Suva 134a, HFA-134a, or HFC-134a) is a hydrofluorocarbon (HFC) and haloalkane refrigerant with thermodynamic properties similar to R-12 (dichlorodifluoromethane) but with insignificant ozone depletion potential and a lower 100-year global warming potential (1,430, compared to R-12's GWP of 10,900). It has the formula CF3CH2F and a boiling point of −26.3 °C (−15.34 °F) at atmospheric pressure. R-134a cylinders are colored light blue. A phaseout and transition to HFO-1234yf and other refrigerants, with GWPs similar to CO2, began in 2012 within the automotive market.

<span class="mw-page-title-main">Gas duster</span> Product used for dusting devices

A gas duster, also known as tinned wind or compressed air, is a product used for cleaning or dusting electronic equipment and other sensitive devices that cannot be cleaned using water.

A coolant is a substance, typically liquid, that is used to reduce or regulate the temperature of a system. An ideal coolant has high thermal capacity, low viscosity, is low-cost, non-toxic, chemically inert and neither causes nor promotes corrosion of the cooling system. Some applications also require the coolant to be an electrical insulator.

<span class="mw-page-title-main">Icemaker</span> Consumer device for making ice, found inside a freezer

An icemaker, ice generator, or ice machine may refer to either a consumer device for making ice, found inside a home freezer; a stand-alone appliance for making ice, or an industrial machine for making ice on a large scale. The term "ice machine" usually refers to the stand-alone appliance.

<span class="mw-page-title-main">Cryoablation</span> Process using extreme cold to destroy tissue

Cryoablation is a process that uses extreme cold to destroy tissue. Cryoablation is performed using hollow needles (cryoprobes) through which cooled, thermally conductive fluids are circulated. Cryoprobes are positioned adjacent to the target in such a way that the freezing process will destroy the diseased tissue. Once the probes are in place, the attached cryogenic freezing unit removes heat from ("cools") the tip of the probe and by extension from the surrounding tissues.

Cold spray may refer to:

<span class="mw-page-title-main">Cryopreservation</span> Process to preserve biological matter

Cryopreservation or cryoconservation is a process where biological material - cells, tissues, or organs - are frozen to preserve the material for an extended period of time. At low temperatures any cell metabolism which might cause damage to the biological material in question is effectively stopped. Cryopreservation is an effective way to transport biological samples over long distances, store samples for prolonged periods of time, and create a bank of samples for users. Molecules, referred to as cryoprotective agents (CPAs), are added to reduce the osmotic shock and physical stresses cells undergo in the freezing process. Some cryoprotective agents used in research are inspired by plants and animals in nature that have unique cold tolerance to survive harsh winters, including: trees, wood frogs, and tardigrades. The first human corpse to be frozen with the hope of future resurrection was James Bedford's, a few hours after his cancer-caused death in 1967.[15] Bedford's is the only cryonics corpse frozen before 1974 still frozen today.

<span class="mw-page-title-main">Pumpable ice technology</span> Type of technology to produce and use fluids or secondary refrigerants

Pumpable icetechnology (PIT) uses thin liquids, with the cooling capacity of ice. Pumpable ice is typically a slurry of ice crystals or particles ranging from 5 micrometers to 1 cm in diameter and transported in brine, seawater, food liquid, or gas bubbles of air, ozone, or carbon dioxide.

<span class="mw-page-title-main">Aerosol burn</span> Medical condition

An aerosol frostbite of the skin is an injury to the body caused by the pressurized gas within an aerosol spray cooling quickly, with the sudden drop in temperature sufficient to cause frostbite to the applied area. Medical studies have noted an increase of this practice, known as "frosting", in pediatric and teenage patients.

References

  1. Shadgan B, Med S, Pakravan AH, Hoens A, Reid WD. Subcutaneous and Intramuscular Hemodynamics and Oxygenation After Cold-Spray Application as Monitored by Near-Infrared Spectroscopy. J Athl Train. 2015;50(8):800-805. doi:10.4085/1062-6050-50.6.02
  2. Knight KL, Brucker JB, Stoneman PD, Rubley MD. Muscle injury management with cryotherapy. Athl Ther Today. 2000;5(4):26–30.
  3. US 5798169,Smith, Christopher A.,"Self-containing tamper evident seal",published 1998-08-25, assigned to Sealed Air Corp.
  4. "A Pharmacist's Guide to OTC Therapy: OTC Treatments for Warts". July 2006. Archived from the original on 2010-06-17. Retrieved 2017-08-26.
  5. "Guidance Note for medical practitioners and hospitals - Prevention and management of tick bites in Australia" (PDF). January 2023.
  6. Widman, Miriam (June 16, 2015). "'Magic' freeze sprays can do deep damage". Deutsche Welle. Retrieved August 26, 2017.
  7. BBC Biochemical, "Histological Freezing Spray," S91 datasheet, March 2017. https://www.statlab.com/pdfs/sds/Histological_Freezing_Spray_Safety_Data_Sheet.pdf
  8. Fernandez-Duque1, Eduardo (2003), "Field Methods for Capturing and Marking Azarai Night Monkeys" (PDF), International Journal of Primatology, 24 (5): 1113–1120, doi:10.1023/a:1026284430453, S2CID   44002464 , retrieved 28 August 2017{{citation}}: CS1 maint: numeric names: authors list (link)