GMCL1

GMCL1
Identifiers
Aliases	GMCL1 , BTBD13, GCL, GCL1, SPATA29, germ cell-less, spermatogenesis associated 1, germ cell-less 1, spermatogenesis associated
External IDs	MGI: 1345156 HomoloGene: 8021 GeneCards: GMCL1
Gene location (Human)
Chr.	Chromosome 2 (human)
End	69,881,384 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	86,710,365 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; Achilles tendon; ; rectum; ; monocyte; ; islet of Langerhans; ; duodenum; ; jejunal mucosa; ; ganglionic eminence; ; bone marrow; ; testicle;
	Top expressed in
	spermatocyte; ; superior cervical ganglion; ; seminiferous tubule; ; cumulus cell; ; molar; ; trigeminal ganglion; ; medullary collecting duct; ; hair follicle; ; secondary oocyte; ; ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ; identical protein binding ;
Cellular component	nuclear matrix ; nuclear envelope ; ubiquitin ligase complex ; nucleus ;
Biological process	multicellular organism development ; cell differentiation ; regulation of transcription, DNA-templated ; spermatogenesis ;
	Sources:Amigo / QuickGO
Orthologs
	64395
	23885
	ENSG00000087338
	ENSMUSG00000001157
	Q96IK5
	Q920G9
	NM_178439
	NM_011818
	NP_848526
	NP_035948
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Germ cell-less, spermatogenesis associated 1 is a protein that in humans is encoded by the GMCL1 gene. ^[5]

Function

This gene encodes a nuclear envelope protein that appears to be involved in spermatogenesis, either directly or by influencing genes that play a more direct role in the process. This multi-exon locus is the homolog of the mouse and drosophila germ cell-less gene but the human genome also contains a single-exon locus on chromosome 5 that contains an open reading frame capable of encoding a highly related protein.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000087338 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001157 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Germ cell-less, spermatogenesis associated 1" . Retrieved 2015-09-17.

GMCL1

Contents

Function

Related Research Articles

References

Further reading