GPBP1

GPBP1
Identifiers
Aliases	GPBP1 , GPBP, SSH6, VASCULIN, GC-rich promoter binding protein 1
External IDs	OMIM: 608412; MGI: 1920524; HomoloGene: 11292; GeneCards: GPBP1; OMA:GPBP1 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) [1] Band 5q11.2 Start 57,173,948 bp [1] End 57,264,679 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13|13 D2.2 Start 111,562,214 bp [2] End 111,626,645 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone cardiac muscle tissue of right atrium Achilles tendon corpus callosum gonad myocardium of left ventricle mucosa of paranasal sinus epithelium of nasopharynx ganglionic eminence mucosa of ileum Top expressed in zygote primary oocyte secondary oocyte blood cumulus cell tail of embryo spermatid medial ganglionic eminence hand vestibular sensory epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding protein binding Cellular component cytoplasm intracellular membrane-bounded organelle nucleus cytosol plasma membrane Biological process positive regulation of transcription, DNA-templated regulation of transcription, DNA-templated transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 65056 73274 Ensembl ENSG00000062194 ENSMUSG00000032745 UniProt Q86WP2 Q6NXH3 RefSeq (mRNA) NM_001127235 NM_001127236 NM_001203246 NM_022913 NM_001331037 NM_001122963 NM_028487 NM_001361923 NM_001361924 NM_001361925 NM_001361926 RefSeq (protein) NP_001120707 NP_001120708 NP_001190175 NP_001317966 NP_075064 NP_001116435 NP_082763 NP_001348852 NP_001348853 NP_001348854 NP_001348855 Location (UCSC) Chr 5: 57.17 – 57.26 Mb Chr 13: 111.56 – 111.63 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Vasculin is a protein that in humans is encoded by the GPBP1 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000062194 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032745 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bijnens AP, Gils A, Jutten B, Faber BC, Heeneman S, Kitslaar PJ, Tordoir JH, de Vries CJ, Kroon AA, Daemen MJ, Cleutjens KB (Oct 2003). "Vasculin, a novel vascular protein differentially expressed in human atherogenesis". Blood. 102 (8): 2803–10. doi: 10.1182/blood-2003-01-0306 . PMID   12842993.
6. "Entrez Gene: GPBP1 GC-rich promoter binding protein 1".

Further reading

• Szafranski K, Schindler S, Taudien S, et al. (2008). "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns". Genome Biol. 8 (8): R154. doi: 10.1186/gb-2007-8-8-r154 . PMC   2374985 . PMID   17672918.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Hsu LC, Liu S, Abedinpour F, et al. (2003). "The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription". Mol. Cell. Biol. 23 (23): 8773–85. doi:10.1128/MCB.23.23.8773-8785.2003. PMC   262660 . PMID   14612417.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.