GPHB5

Last updated
GPHB5
Identifiers
Aliases GPHB5 , B5, GPB5, ZLUT1, glycoprotein hormone beta 5, glycoprotein hormone subunit beta 5
External IDs OMIM: 609652 MGI: 2156540 HomoloGene: 18476 GeneCards: GPHB5
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_145171

NM_175644

RefSeq (protein)

NP_660154

NP_783575

Location (UCSC) Chr 14: 63.31 – 63.32 Mb Chr 12: 75.46 – 75.46 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Glycoprotein hormone beta-5 is a protein that in humans is encoded by the GPHB5 gene. [5]

GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002).[supplied by OMIM] [5]

Related Research Articles

<span class="mw-page-title-main">Thyrotropin receptor</span> Mammalian protein found in Homo sapiens

The thyrotropin receptor is a receptor that responds to thyroid-stimulating hormone and stimulates the production of thyroxine (T4) and triiodothyronine (T3). The TSH receptor is a member of the G protein-coupled receptor superfamily of integral membrane proteins and is coupled to the Gs protein.

<span class="mw-page-title-main">Thyroid hormone receptor beta</span> Protein-coding gene in the species Homo sapiens

Thyroid hormone receptor beta (TR-beta) also known as nuclear receptor subfamily 1, group A, member 2 (NR1A2), is a nuclear receptor protein that in humans is encoded by the THRB gene.

<span class="mw-page-title-main">GPR39</span> Protein-coding gene in the species Homo sapiens

G-protein coupled receptor 39 is a protein that in humans is encoded by the GPR39 gene.

<span class="mw-page-title-main">LGR4</span> Protein-coding gene in the species Homo sapiens

Leucine-rich repeat-containing G-protein coupled receptor 4 is a protein that in humans is encoded by the LGR4 gene. LGR4 is known to have a role in the development of the male reproductive tract, eyelids, hair and bone.

<span class="mw-page-title-main">Relaxin/insulin-like family peptide receptor 2</span> Protein-coding gene in the species Homo sapiens

Relaxin/insulin-like family peptide receptor 2, also known as RXFP2, is a human G-protein coupled receptor.

<span class="mw-page-title-main">LGR6</span> Protein-coding gene in the species Homo sapiens

Leucine-rich repeat-containing G-protein coupled receptor 6 is a protein that in humans is encoded by the LGR6 gene. Along with the other G-protein coupled receptors LGR4 and LGR5, LGR6 is a Wnt signaling pathway mediator. LGR6 also acts as an epithelial stem cell marker in squamous cell carcinoma in mice in vivo.

<span class="mw-page-title-main">FSHB</span> Protein-coding gene in the species Homo sapiens

Follitropin subunit beta also known as follicle-stimulating hormone beta subunit (FSH-B) is a protein that in humans is encoded by the FSHB gene. Alternative splicing results in two transcript variants encoding the same protein.

<span class="mw-page-title-main">PCK1</span> Protein-coding gene in the species Homo sapiens

Phosphoenolpyruvate carboxykinase 1 (soluble), also known as PCK1, is an enzyme which in humans is encoded by the PCK1 gene.

Progonadoliberin-2 is a protein that in humans is encoded by the GNRH2 gene.

<span class="mw-page-title-main">THRAP3</span> Protein-coding gene in the species Homo sapiens

Thyroid hormone receptor-associated protein 3 is a protein that in humans is encoded by the THRAP3 gene.

<span class="mw-page-title-main">THRSP</span> Protein-coding gene in the species Homo sapiens

Thyroid hormone-inducible hepatic protein is a protein that in humans is encoded by the THRSP gene.

<span class="mw-page-title-main">CYTH3</span> Protein-coding gene in the species Homo sapiens

Cytohesin-3 is a protein that in humans is encoded by the CYTH3 gene.

<span class="mw-page-title-main">MED16</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 16 is an enzyme that in humans is encoded by the MED16 gene.

<span class="mw-page-title-main">GLRA2</span> Protein-coding gene in the species Homo sapiens

Glycine receptor subunit alpha-2 is a protein that in humans is encoded by the GLRA2 gene.

<span class="mw-page-title-main">Luteinizing hormone beta polypeptide</span> Protein-coding gene in the species Homo sapiens

Luteinizing hormone subunit beta also known as lutropin subunit beta or LHβ is a polypeptide that in association with an alpha subunit common to all gonadotropin hormones forms the reproductive signaling molecule luteinizing hormone. In humans it is encoded by the LHB gene.

<span class="mw-page-title-main">GPHA2</span> Protein-coding gene in the species Homo sapiens

Glycoprotein hormone alpha-2 is a protein that in humans is encoded by the GPHA2 gene.

<span class="mw-page-title-main">TRIP12</span> Gene of the species Homo sapiens

Probable E3 ubiquitin-protein ligase TRIP12 is an enzyme that in humans is encoded by the TRIP12 gene.

<span class="mw-page-title-main">HMGN3</span> Protein-coding gene in the species Homo sapiens

High mobility group nucleosome-binding domain-containing protein 3 is a protein that in humans is encoded by the HMGN3 gene.

<span class="mw-page-title-main">LHX2</span> Protein-coding gene in the species Homo sapiens

LIM/homeobox protein Lhx2 is a protein that in humans is encoded by the LHX2 gene.

<span class="mw-page-title-main">TSHB</span> Protein-coding gene in the species Homo sapiens

Thyroid stimulating hormone, beta also known as TSHB is a protein which in humans is encoded by the TSHB gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000179600 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000048982 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: GPHB5 glycoprotein hormone beta 5".

Z. Gong, W. Wang, K. El Omari, A. A. Lebedev, O. B. Clarke, W. A. Hendrickson, Crystal structure of LGR ligand alpha2/beta5 from Caenorhabditis elegans with implications for the evolution of glycoprotein hormones. Proc Natl Acad Sci U S A 120 (1), e2218630120 (2023). https://www.pnas.org/doi/10.1073/pnas.2218630120#

Further reading