GPRASP2

GPRASP2
Identifiers
Aliases	GPRASP2 , GASP2, G protein-coupled receptor associated sorting protein 2, DFNX7
External IDs	OMIM: 300969; MGI: 2442071; HomoloGene: 133816; GeneCards: GPRASP2; OMA:GPRASP2 - orthologs
Gene location (Human) Chr. X chromosome (human) [1] Band Xq22.1 Start 102,712,445 bp [1] End 102,717,733 bp [1]
Gene location (Mouse) Chr. X chromosome (mouse) [2] Band X F1|X 57.3 cM Start 134,739,783 bp [2] End 134,745,479 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell Brodmann area 23 middle temporal gyrus pons postcentral gyrus superior vestibular nucleus cardiac muscle tissue of right atrium entorhinal cortex lateral nuclear group of thalamus superior frontal gyrus Top expressed in dorsomedial hypothalamic nucleus paraventricular nucleus of hypothalamus arcuate nucleus ventromedial nucleus median eminence lateral hypothalamus suprachiasmatic nucleus ventral tegmental area dorsal tegmental nucleus central gray substance of midbrain More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 114928 245607 Ensembl ENSG00000158301 ENSMUSG00000072966 UniProt Q96D09 Q8BUY8 RefSeq (mRNA) NM_138437 NM_001004051 NM_001184874 NM_001184875 NM_001184876 NM_001163015 NM_001163016 NM_001163017 NM_001359371 RefSeq (protein) NP_001186747 NP_001337197 NP_001337198 NP_001337199 NP_001004051 NP_001171803 NP_001171804 NP_001171805 NP_612446 NP_001156487 NP_001156488 NP_001156489 NP_001346300 Location (UCSC) Chr X: 102.71 – 102.72 Mb Chr X: 134.74 – 134.75 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

G-protein coupled receptor-associated sorting protein 2 is a protein that in humans is encoded by the GPRASP2 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000158301 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000072966 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Simonin F, Karcher P, Boeuf JJ, Matifas A, Kieffer BL (Apr 2004). "Identification of a novel family of G protein-coupled receptor associated sorting proteins". J Neurochem. 89 (3): 766–75. doi: 10.1111/j.1471-4159.2004.02411.x . PMID   15086532.
6. "Entrez Gene: GPRASP2 G protein-coupled receptor associated sorting protein 2".

Further reading

• Horn SC, Lalowski M, Goehler H, et al. (2007). "Huntingtin interacts with the receptor sorting family protein GASP2". Journal of Neural Transmission. 113 (8): 1081–90. doi:10.1007/s00702-006-0514-6. PMID   16835690. S2CID   9336547.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC   2665286 . PMID   15772651.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Goehler H, Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi: 10.1016/j.molcel.2004.09.016 . PMID   15383276.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.