Gilles Dreyfus

Last updated
Gilles Dreyfus
Born(1951-05-24)May 24, 1951
Nationality French
Alma materParis Faculty of Medicine, Hôpitaux de Paris
Scientific career
Fields Heart Surgery
Institutions Cardio-thoracic center of Monaco
Academic advisors Alain Carpentier, Norman E. Shumway

Gilles Dreyfus (born 24 May 1951) is a French cardiac surgeon.

Contents

Education

Gilles Dreyfus graduated from the Medical Faculty of Paris (Paris V, CHU Broussais – Hotel Dieu). From 1978 to 1983 he was Resident in cardiac surgery at the Hôpitaux de Paris, where he was trained in adult and congenital cardiac surgery guided by Professors Binet, Dubost, Guilmet and Neveux.

From October 1983 to 1987, he was the Chef de Clinique for Professor Alain Carpentier, senior resident and staff surgeon at the Broussais Hospital. From 1987 to 1989, he was Consultant surgeon of the Hôpitaux de Paris, working with Professor Carpentier. In 1983, he trained for 6 months at the University of Stanford to specialize in heart and lung transplantation with Professor N.Shumway. Back in Paris, he started a transplant program at the Broussais Hospital, in the department headed by Professor Carpentier.

In 1989 he became Professor of Cardio-vascular Surgery.

Career

Broussais Hospital, 1983-1989

Gilles Dreyfus started as senior resident/assistant surgeon, before becoming staff surgeon of Professor Carpentier. He acquired a specific training in mitral valve repair and developed new surgical techniques in valve repair with Professor Carpentier, in particular he performed the first mitral valve repair in case of acute endocarditis and he published an article on innovative surgical procedures. [1] He also improved the transplant program at the Broussais Hospital, started by Professor Dubost and discontinued after 4 patients. The program developed rapidly: from 1984 to 1989, more than 200 heart transplants were performed at the Broussais Hospital. An artificial heart project as a bridge to transplant was also developed.

In 1986, he helped Professor Carpentier perform the first artificial heart implant in Europe. During his stay at the Broussais Hospital, Gilles Dreyfus published several articles on heart transplant, such as Total orthotopic heart transplant: an alternative to the standard technique (Annals of Thoracic Surgery 1991), where he described a new technique called total heart transplant.

He was nominated Professor of Cardiovascular Surgery in 1989 by Professor Alain Carpentier.

Foch Hospital, 1989-2001

In November 1989, Gilles Dreyfus became staff surgeon of Professor Daniel Guilmet at the Foch Hospital and Professor of Cardiovascular surgery. [2] He performed more than 500 mitral valve repairs and described new repair techniques such as the papillary muscle repositioning for anterior leaflet and posterior commissural prolapse. He also improved the heart transplant program, from 10 to 25 cases per year, so that the Foch Hospital became the 2nd-3rd most active center in the region of Île-de-France.

Gilles Dreyfus continued the research on artificial hearts as a bridge to transplant, implanting TCI and NOVACOR for the first time in France. In 1998, after Professor Guilmet’s retirement, Gilles Dreyfus became chief of cardiac and vascular surgery of the Foch Hospital, continuing the surgical activity and developing the heart valve repair surgery, the ventricular assist devices and heart transplant programs. [3]

In 2000, French actor Gérard Depardieu underwent coronary artery bypass surgery performed by Professor Dreyfus. [4]

London : Royal Brompton and Harefield, NHS Trust, 2001-2009

In April 2001, Gilles Dreyfus joined Professor Sir Magdi Yacoub at the Harefield Hospital in London, UK. They worked together for 6 months before Professor Dreyfus became director of the cardio-thoracic surgery in October 2001, following Sir Yacoub’s retirement. He was nominated Professor of cardio-thoracic surgery at the Imperial College School of Medicine (2nd University of UK) and then became director of the cardio-thoracic surgery and transplantation at the Harefield Hospital. He also continued his research on mitral valve surgery and on tricuspid valve.

In 2003, he presented a research paper at the AATS annual meeting with a study population of 311 patients, divided in two subgroups: one underwent isolated mitral valve repair, the other mitral valve repair associated to tricuspid valve repair. In this research, professor Dreyfus demonstrated the rationale in treating the tricuspid annulus dilation independently from the presence of tricuspid regurgitation. This principle influenced the guidelines of the international societies of Cardiology, may it be the American College of Cardiology / American Heart Association, or the European Society of Cardiology.

He also focused his research on a new technique to replace the aortic valve, using autologous pericardium. [5] Results of this method, called Cardiomend were presented at the American Society of Thoracic Surgeons annual meeting in 2001 [6] and were the object of two articles. [7]

As Director of one of the largest centers for transplantation in Europe, he led a program of heart and lung transplant and cardiac assist devices. Under his influence, the Harefield group was the first group in Europe to implant the Jarvik 2000, [8] in addition to other assist devices as destination therapy or as bridge-to-recovery in case of heart failure.

While practicing in London, he operated the Queen of Spain's brother, the Queen of England's cousin, the King Constantin of Greece. [9]

In 2002, professor Dreyfus, along with three other famous European surgeons specialized in mitral valve repair, developed the Master of Valve Repair, a training course supported by Edwards Lifesciences, happening twice or thrice a year, where more than 2000 European surgeons have been trained to advanced techniques in mitral valve repair. [10]

Cardio-Thoracic Centre in Monaco

In January 2010, upon the request of Professor Vincent Dor, Gilles Dreyfus was appointed as Medical Director or the Cardio-Thoracic Centre in Monaco, taking over Professor Dor who retired. [11] [12]

Awards and honours

Related Research Articles

<span class="mw-page-title-main">Cardiothoracic surgery</span> Medical specialty involved in surgical treatment of organs inside the thorax

Cardiothoracic surgery is the field of medicine involved in surgical treatment of organs inside the thoracic cavity — generally treatment of conditions of the heart, lungs, and other pleural or mediastinal structures.

<span class="mw-page-title-main">Cardiac surgery</span> Type of surgery performed on the heart

Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease ; to correct congenital heart disease; or to treat valvular heart disease from various causes, including endocarditis, rheumatic heart disease, and atherosclerosis. It also includes heart transplantation.

<span class="mw-page-title-main">Perfusionist</span> Healthcare professional who uses the cardiopulmonary bypass machine

A cardiovascular perfusionist, clinical perfusionist or perfusiologist, and occasionally a cardiopulmonary bypass doctor or clinical perfusion scientist, is a healthcare professional who operates the cardiopulmonary bypass machine during cardiac surgery and other surgeries that require cardiopulmonary bypass to manage the patient's physiological status. As a member of the cardiovascular surgical team, the perfusionist also known as the clinical perfusionist helps maintain blood flow to the body's tissues as well as regulate levels of oxygen and carbon dioxide in the blood, using a heart–lung machine.

<span class="mw-page-title-main">Magdi Yacoub</span> Egyptian retired professor and surgeon (born 1935)

Sir Magdi Habib Yacoub is an Egyptian-British retired professor of cardiothoracic surgery at Imperial College London, best known for his early work in repairing heart valves with surgeon Donald Ross, adapting the Ross procedure, where the diseased aortic valve is replaced with the person's own pulmonary valve, devising the arterial switch operation (ASO) in transposition of the great arteries, and establishing the heart transplantation centre at Harefield Hospital in 1980 with a heart transplant for Derrick Morris, who at the time of his death was Europe's longest-surviving heart transplant recipient. Yacoub subsequently performed the UK's first combined heart and lung transplant in 1983.

<span class="mw-page-title-main">Mitral valve repair</span> Cardiac surgery procedure

Mitral valve repair is a cardiac surgery procedure performed by cardiac surgeons to treat stenosis (narrowing) or regurgitation (leakage) of the mitral valve. The mitral valve is the "inflow valve" for the left side of the heart. Blood flows from the lungs, where it picks up oxygen, through the pulmonary veins, to the left atrium of the heart. After the left atrium fills with blood, the mitral valve allows blood to flow from the left atrium into the heart's main pumping chamber called the left ventricle. It then closes to keep blood from leaking back into the left atrium or lungs when the ventricle contracts (squeezes) to push blood out to the body. It has two flaps, or leaflets, known as cusps.

Walter Randolph "Ranny" Chitwood Jr. is known for his work as a cardiothoracic surgeon at the Brody School of Medicine at East Carolina University located in Greenville, North Carolina.

Alain Frédéric Carpentier is a French cardiac surgeon whom the President of the American Association for Thoracic Surgery calls the "father of modern mitral valve repair". He is most well-known for the development and popularization of a number of mitral valve repair techniques. In 1996, he performed the first minimally invasive mitral valve repair in the world and in 1998 he performed the first robotic mitral valve repair with the da Vinci Surgical System prototype. He is the recipient of the 2007 Lasker Prize.

<span class="mw-page-title-main">Redmond Burke</span> American surgeon

Redmond P. Burke is an American congenital heart surgeon, innovator, software developer, author, inventor, and founder of The Congenital Heart Institute at Miami Children's Hospital in Miami, Florida. He starred in the ABC pilot television show Miracle Workers . Burke has been recognized as one of the world's most innovative surgeons, and for his use of information technology to improve surgical outcomes.

David H. Adams is an American cardiac surgeon and the Marie-Josée and Henry R. Kravis Professor and Chairman of the Department of Cardiothoracic Surgery, Icahn School of Medicine at Mount Sinai Hospital in New York City. Dr. Adams is a recognized leader in the field of heart valve surgery and mitral valve reconstruction. As director of Mount Sinai Mitral Valve Repair Center, he has set national benchmarks with >99% degenerative mitral valve repair rates, while running one of the largest valve repair programs in the United States. Dr. Adams is the co-inventor of 2 mitral valve annuloplasty repair rings – the Carpentier-McCarthy-Adams IMR ETlogix Ring and the Carpentier-Edwards Physio II Annuloplasty Ring, and is a senior consultant with royalty agreements with Edwards Lifesciences. He is also the inventor of the Tri-Ad Adams Tricuspid Annuloplasty ring with a royalty agreement with Medtronic. He is a co-author with Professor Alain Carpentier of the benchmark textbook in mitral valve surgery Carpentier's Reconstructive Valve Surgery. He is also the National Co-Principal Investigator of the FDA pivotal trial of the Medtronic-CoreValve transcatheter aortic valve replacement device.

<span class="mw-page-title-main">Robert E. Michler</span> Heart surgeon in the United States

Robert E. Michler is an American heart surgeon specializing in aortic and mitral valve repair, coronary artery bypass surgery, aneurysm surgery, and management of the failing heart. In 2017, Michler received the Vladimir Borakovsky Prize in Moscow from the Ministry of Health of the Russian Federation for “his personal contributions to the development of cardiovascular surgery”.

<span class="mw-page-title-main">Marian Ionescu</span> British cardiac surgeon (1929–2023)

Marian Ion Ionescu was a Romanian-born British cardiac surgeon. His interest in heart surgery covered several aspects of this specialty. He was an inventor of surgical devices, mostly artificial heart valves, a scientist in the broad term and a medical educator. Ionescu died on 12 October 2023, at the age of 94.

Heart valve repair is a cardiac surgery procedure, carried out to repair one or more faulty heart valves. In some valvular heart diseases repair where possible is preferable to valve replacement. A mechanical heart valve is a replacement valve that is not itself subject to repair.

The German Hospital Tirana is a hospital in Tirana, Albania.

Mitral valve annuloplasty is a surgical technique for the repair of leaking mitral valves. Due to various factors, the two leaflets normally involved in sealing the mitral valve to retrograde flow may not coapt properly. Surgical repair typically involves the implantation of a device surrounding the mitral valve, called an annuloplasty device, which pulls the leaflets together to facilitate coaptation and aids to re-establish mitral valve function.

Dr R Ravi Kumar is an Indian heart surgeon, and a pioneer in robot-assisted heart surgery.

<span class="mw-page-title-main">Nagarur Gopinath</span> Indian cardiothoracic surgeon (1922 - 2007)

Nagarur Gopinath was an Indian surgeon and one of the pioneers of cardiothoracic surgery in India. He is credited with the first successful performance of open heart surgery in India which he performed in 1962. He served as the honorary surgeon to two Presidents of India and was a recipient of the fourth highest Indian civilian award of Padma Shri in 1974 and Dr. B. C. Roy Award, the highest Indian medical award in 1978 from the Government of India.

<span class="mw-page-title-main">Hans-Joachim Schäfers</span> German surgeon, as well as cardiac, thoracic, and vascular surgeon

Hans-Joachim Schäfers is a German surgeon, as well as cardiac, thoracic, and vascular surgeon and university professor. He is director of the department of Thoracic and Cardiovascular Surgery at the Saarland University Medical Center in Homburg/Saar, Germany. He is known for his activities in aortic valve repair, aortic surgery, and pulmonary endarterectomy.

<span class="mw-page-title-main">Francis Fontan</span> French cardiologist and surgeon

Francis Fontan was a French cardiologist and cardiothoracic surgeon best known for developing the Fontan procedure, a surgical procedure used to treat some forms of congenital heart disease.

<span class="mw-page-title-main">Anil Bhan</span> Indian cardiologist

Dr. Anil Bhan is the Chairman of Cardiac Surgery Heart Institute, Medanta Hospital, Gurugram, India. He graduated from Medical College Srinagar. He has the largest experience in aortic surgery in India since he has designed and developed more than 50 surgical instruments in the field of cardiac surgery. He was one of the team members to perform the first successful heart transplant in India in1994. He served as a co-founder of Max Heart and Vascular Institute, Saket, New Delhi, Director and Chief Co-Ordinator, Cardio thoracic and Vascular Surgery, MHVI, Saket.Additional Professor, Cardiothoracic Surgery and Vascular Surgery, AIIMS, New Delhi.

<span class="mw-page-title-main">Andrew Logan (surgeon)</span> British cardio-thoracic surgeon

Andrew Logan, FRCS, FRCSEd was a British cardiothoracic surgeon. For most of his career he worked in Edinburgh where he established the specialty of cardio-thoracic surgery. He devised a mitral valve dilator to treat mitral stenosis and this technique, modified by Oswald Tubbs and by Russell Brock, became widely used to treat this condition. He assisted at the first pneumonectomy in the UK and performed the first lung transplant in the UK.

References

  1. Valve repair in acute endocarditis Archived 2008-07-23 at the Wayback Machine , Ann Thorac Surg 1990;49:706-713
  2. Origine et historique de l'ADETEC Archived 2012-02-11 at the Wayback Machine , Adetec.eu(in French)
  3. (PDF) Quatre Nouveaux Chefs de Service prennent leur fonction en octobre [ permanent dead link ], Fondation Foch Website(in French)
  4. Mark Fuerst, Pastille Day: Gerard Depardieu recovering from bypass operation, The Heart.org, 14 July 2000
  5. NHS stories: Making better heart valves, BBC , 17 janvier 2004
  6. The First Totally Stentless and Reproducible Autologous Pericardial Valve Archived 2012-02-08 at the Wayback Machine , STS, 2006
  7. First CardioMend autologous pericardial aortic valve reconstruction, m2.com
  8. Midterm experience with the Jarvik 2000 axial flow left ventricular assist device, Research Gate, 08/2007; 134(1):199-203. doi : 10.1016/j.jtcvs.2007.01.002
  9. Press Release - 29 May 2009, The greek royal family website, 29 may 2009
  10. Master of valve repair program, may 2005 Archived 2005-04-28 at the Wayback Machine , The cardiothoraci surgery network
  11. Monaco Au Centre cardio-thoracique Vincent Dor passe la main, Nice Matin, January 7, 2010 (in French)
  12. [ unreliable source? ] Le professeur Gilles Dreyfus au CCM de Monaco, Nouvel Obs, 7 janvier 2010 (in French)

Further reading