Guanylate binding protein family member 6

GBP6
Identifiers
Aliases	GBP6 , guanylate binding protein family member 6
External IDs	OMIM: 612467 MGI: 97072 HomoloGene: 128731 GeneCards: GBP6
Gene location (Human)
Chr.	Chromosome 1 (human)
End	89,388,160 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	105,287,452 bp
RNA expression pattern
	Top expressed in
	cavity of mouth; ; body of tongue; ; superior surface of tongue; ; thymus; ; vulva; ; vagina; ; human penis; ; bronchial epithelial cell; ; minor salivary gland; ; right coronary artery;
	Top expressed in
	thymus; ; spleen; ; lung; ; heart; ; pancreas; ; islet of Langerhans; ; jejunum; ; ileum; ; muscle tissue; ; ovary;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding ; GTP binding ; GTPase activity ;
Cellular component	extracellular exosome ; symbiont-containing vacuole membrane ; cytoplasmic vesicle ;
Biological process	defense response to bacterium ; immune response ; cellular response to interferon-gamma ; defense response to protozoan ; defense response to Gram-positive bacterium ;
	Sources:Amigo / QuickGO
Orthologs
	163351
	17472
	ENSG00000183347
	ENSMUSG00000079363
	Q6ZN66
	n/a
	NM_198460 ; NM_001320257
NM_001256005 ; NM_008620 ; NM_001359079 ; NM_001359080 ; NM_001359081 ;
	NM_001359082
	NP_001307186 ; NP_940862
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 10, 2022

Guanylate binding protein family member 6 is a protein that in humans is encoded by the GBP6 gene. ^[5]

Function

Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).

Related Research Articles

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Guanylate cyclase activator 2B is a protein that in humans is encoded by the GUCA2B gene.

Forkhead box S1 is a protein that in humans is encoded by the FOXS1 gene.

Retinol binding protein 7 is a protein that in humans is encoded by the RBP7 gene.

RFX family member 8, lacking RFX DNA binding domain is a protein that in humans is encoded by the RFX8 gene.

Single-stranded DNA-binding protein 4 is a protein that in humans is encoded by the SSBP4 gene.

Guanine nucleotide-binding protein subunit alpha-14 is a protein that in humans is encoded by the GNA14 gene. G₁₄α is a member of the Gq alpha subunit family, and functions as a constituent of a heterotrimeric G protein in cell signal transduction.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000183347 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000079363 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Guanylate binding protein family member 6" . Retrieved 2017-07-27.

Guanylate binding protein family member 6

Contents

Function

Related Research Articles

References

Further reading