HABP4

HABP4
Identifiers
Aliases	HABP4 , IHABP-4, IKi-1/57, SERBP1L, hyaluronan binding protein 4
External IDs	OMIM: 617369; MGI: 1891713; HomoloGene: 8615; GeneCards: HABP4; OMA:HABP4 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q22.32 Start 96,450,169 bp [1] End 96,491,336 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13 B3|13 33.26 cM Start 64,309,638 bp [2] End 64,334,351 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell nucleus accumbens olfactory bulb beta cell putamen right frontal lobe caudate nucleus cingulate gyrus amygdala anterior cingulate cortex Top expressed in superior frontal gyrus dentate gyrus of hippocampal formation granule cell primary visual cortex central gray substance of midbrain seminiferous tubule medial vestibular nucleus dorsal tegmental nucleus neural layer of retina right kidney deep cerebellar nuclei More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding RNA binding SUMO binding Cellular component extracellular region sarcomere nucleus cytoplasm nucleolus Cajal body sarcoplasm nuclear body nuclear speck gemini of coiled bodies cytosol cytoplasmic stress granule Biological process negative regulation of DNA binding cellular response to mechanical stimulus platelet degranulation regulation of transcription, DNA-templated transcription, DNA-templated positive regulation of RNA splicing positive regulation of translational initiation mRNA processing regulation of translation RNA splicing PML body organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22927 56541 Ensembl ENSG00000130956 ENSMUSG00000021476 UniProt Q5JVS0 Q9JKS5 RefSeq (mRNA) NM_014282 NM_019986 RefSeq (protein) NP_055097 NP_064370 Location (UCSC) Chr 9: 96.45 – 96.49 Mb Chr 13: 64.31 – 64.33 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Intracellular hyaluronan-binding protein 4 is a protein that in humans is encoded by the HABP4 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000130956 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021476 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kobarg J, Schnittger S, Fonatsch C, Lemke H, Bowen MA, Buck F, Hansen HP (May 1998). "Characterization, mapping and partial cDNA sequence of the 57-kD intracellular Ki-1 antigen". Exp Clin Immunogenet. 14 (4): 273–80. PMID   9523163.
6. Huang L, Grammatikakis N, Yoneda M, Banerjee SD, Toole BP (Nov 2000). "Molecular characterization of a novel intracellular hyaluronan-binding protein". J Biol Chem. 275 (38): 29829–39. doi: 10.1074/jbc.M002737200 . PMID   10887182.
7. "Entrez Gene: HABP4 hyaluronan binding protein 4".

Further reading

• Rohde D, Hansen H, Hafner M, et al. (1992). "Cellular localizations and processing of the two molecular forms of the Hodgkin-associated Ki-1 (CD30) antigen. The protein kinase Ki-1/57 occurs in the nucleus". Am. J. Pathol. 140 (2): 473–82. PMC   1886443 . PMID   1310832.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Lemos TA, Passos DO, Nery FC, Kobarg J (2003). "Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3". FEBS Lett. 533 (1–3): 14–20. doi: 10.1016/S0014-5793(02)03737-7 . PMID   12505151. S2CID   41197943.
• Nery FC, Passos DO, Garcia VS, Kobarg J (2004). "Ki-1/57 interacts with RACK1 and is a substrate for the phosphorylation by phorbol 12-myristate 13-acetate-activated protein kinase C". J. Biol. Chem. 279 (12): 11444–55. doi: 10.1074/jbc.M306672200 . PMID   14699138.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID   15146197. S2CID   27764390.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Kobarg CB, Kobarg J, Crosara-Alberto DP, et al. (2005). "MEF2C DNA-binding activity is inhibited through its interaction with the regulatory protein Ki-1/57". FEBS Lett. 579 (12): 2615–22. doi: 10.1016/j.febslet.2005.03.078 . PMID   15862299. S2CID   26654365.
• Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl: 11858/00-001M-0000-0010-8592-0 . PMID   16169070. S2CID   8235923.
• Nery FC, Rui E, Kuniyoshi TM, Kobarg J (2006). "Evidence for the interaction of the regulatory protein Ki-1/57 with p53 and its interacting proteins". Biochem. Biophys. Res. Commun. 341 (3): 847–55. doi:10.1016/j.bbrc.2006.01.036. PMID   16455055.
• Passos DO, Bressan GC, Nery FC, Kobarg J (2006). "Ki-1/57 interacts with PRMT1 and is a substrate for arginine methylation". FEBS J. 273 (17): 3946–61. doi: 10.1111/j.1742-4658.2006.05399.x . PMID   16879614. S2CID   25895297.