HACL1 (gene)

HACL1
Identifiers
Aliases	HACL1 , 2-HPCL, HPCL, HPCL2, PHYH2, 2-hydroxyacyl-CoA lyase 1
External IDs	OMIM: 604300 MGI: 1929657 HomoloGene: 5794 GeneCards: HACL1
Gene location (Human)
Chr.	Chromosome 3 (human)
End	15,601,852 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	31,363,243 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; right lobe of liver; ; secondary oocyte; ; Achilles tendon; ; deltoid muscle; ; islet of Langerhans; ; gastrocnemius muscle; ; corpus epididymis; ; bronchial epithelial cell;
	Top expressed in
	liver; ; lip; ; renal cortex; ; spermatocyte; ; proximal tubule; ; kidney; ; white adipose tissue; ; bone marrow; ; zone of skin; ; spermatid;
	More reference expression data
	n/a
Gene ontology
Molecular function	thiamine pyrophosphate binding ; signaling receptor binding ; protein binding ; catalytic activity ; magnesium ion binding ; metal ion binding ; lyase activity ; carbon-carbon lyase activity ; identical protein binding ;
Cellular component	peroxisome ; peroxisomal matrix ; cytosol ;
Biological process	fatty acid alpha-oxidation ; protein complex oligomerization ; fatty acid metabolic process ; protein targeting to peroxisome ; lipid metabolism ;
	Sources:Amigo / QuickGO
Orthologs
	26061
	56794
	ENSG00000131373
	ENSMUSG00000021884
	Q9UJ83
	Q9QXE0
	NM_001284413 ; NM_001284415 ; NM_001284416 ; NM_012260
	NM_019975
	NP_001271342 ; NP_001271344 ; NP_001271345 ; NP_036392
	NP_064359
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

2-hydroxyacyl-CoA lyase 1 is a protein that in humans is encoded by the HACL1 gene. ^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000131373 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021884 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: 2-hydroxyacyl-CoA lyase 1" . Retrieved 2016-04-10.

HACL1 (gene)

Related Research Articles

References

Further reading