HAGH

Last updated
HAGH
Protein HAGH PDB 1qh3.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases HAGH , GLO2, GLX2, GLXII, HAGH1, hydroxyacylglutathione hydrolase
External IDs OMIM: 138760; MGI: 95745; HomoloGene: 3890; GeneCards: HAGH; OMA:HAGH - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001040427
NM_001286249
NM_005326
NM_001363912
NM_001363914

NM_001159626
NM_024284

RefSeq (protein)

NP_001035517
NP_001273178
NP_005317
NP_001350841
NP_001350843

NP_001153098
NP_077246

Location (UCSC) Chr 16: 1.8 – 1.83 Mb Chr 17: 25.06 – 25.08 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Hydroxyacylglutathione hydrolase, mitochondrial is an enzyme that in humans is encoded by the HAGH gene. [5] [6] [7]

The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. [7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000063854 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024158 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Mulley JC, Callen DF (Feb 1987). "New regional localisations for HAGH and PGP on human chromosome 16". Hum Genet. 74 (4): 423–4. doi:10.1007/BF00280498. PMID   3025077. S2CID   19620852.
  6. Honey NK, Shows TB (Apr 1982). "Assignment of the glyoxalase II gene (HAGH) to human chromosome 16". Hum Genet. 58 (4): 358–61. doi:10.1007/bf00282815. PMID   7327557. S2CID   10452468.
  7. 1 2 "Entrez Gene: HAGH hydroxyacylglutathione hydrolase".

Further reading