HAUS3

HAUS3
Identifiers
Aliases	HAUS3 , C4orf15, IT1, dgt3, HAUS augmin like complex subunit 3
External IDs	OMIM: 613430; MGI: 2387633; HomoloGene: 75209; GeneCards: HAUS3; OMA:HAUS3 - orthologs
Gene location (Human) Chr. Chromosome 4 (human) [1] Band 4p16.3 Start 2,078,998 bp [1] End 2,242,276 bp [1]
Gene location (Mouse) Chr. Chromosome 5 (mouse) [2] Band 5 B2|5 17.84 cM Start 34,311,224 bp [2] End 34,326,871 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte gonad Achilles tendon ventricular zone oral cavity visceral pleura parietal pleura ganglionic eminence bone marrow skin of thigh Top expressed in primary oocyte secondary oocyte zygote primitive streak maxillary prominence mandibular prominence abdominal wall thymus epiblast tail of embryo More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding molecular function Cellular component microtubule cytoskeleton cytoplasm microtubule organizing center centrosome microtubule HAUS complex cytoskeleton mitochondrion nucleoplasm cytosol spindle intercellular bridge mitotic spindle Biological process spindle assembly cell cycle cell division G2/M transition of mitotic cell cycle ciliary basal body-plasma membrane docking centrosome cycle regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79441 231123 Ensembl ENSG00000214367 ENSMUSG00000079555 UniProt Q68CZ6 Q8QZX2 RefSeq (mRNA) NM_024511 NM_001303143 NM_146159 RefSeq (protein) NP_001290072 NP_078787 NP_666271 Location (UCSC) Chr 4: 2.08 – 2.24 Mb Chr 5: 34.31 – 34.33 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

HAUS augmin-like complex subunit 3 is a protein that in humans is encoded by the HAUS3 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000214367 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000079555 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: HAUS augmin-like complex".
6. Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, Tagliaferro A, Poser I, Hutchins JR, Hegemann B, Pinchev D, Buchholz F, Peters JM, Hyman AA, Gingras AC, Pelletier L (May 2009). "HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity". Curr. Biol. 19 (10): 816–26. Bibcode:2009CBio...19..816L. doi: 10.1016/j.cub.2009.04.033 . PMID   19427217. S2CID   2893122.

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Uehara R, Nozawa RS, Tomioka A, et al. (2009). "The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells". Proc. Natl. Acad. Sci. U.S.A. 106 (17): 6998–7003. Bibcode:2009PNAS..106.6998U. doi: 10.1073/pnas.0901587106 . PMC   2668966 . PMID   19369198.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.