HDGFRP3

HDGFL3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1N27
Identifiers
Aliases	HDGFL3 , CGI-142, HDGF-2, HDGF2, HRP-3, HDGFRP3, hepatoma-derived growth factor, related protein 3, HDGF like 3
External IDs	OMIM: 616643 MGI: 1352760 HomoloGene: 32196 GeneCards: HDGFL3
Gene location (Human)
Chr.	Chromosome 15 (human)
End	83,207,823 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	81,584,221 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; Achilles tendon; ; Brodmann area 23; ; entorhinal cortex; ; postcentral gyrus; ; orbitofrontal cortex; ; corpus epididymis; ; Region I of hippocampus proper; ; endothelial cell; ; superior frontal gyrus;
	Top expressed in
	barrel cortex; ; ganglionic eminence; ; medial ganglionic eminence; ; maxillary prominence; ; ventromedial nucleus; ; paraventricular nucleus of hypothalamus; ; piriform cortex; ; olfactory bulb; ; olfactory tubercle; ; prefrontal cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	microtubule binding ; tubulin binding ; growth factor activity ;
Cellular component	cytoplasm ; cytosol ; nucleus ; nucleoplasm ; extracellular region ;
Biological process	negative regulation of microtubule depolymerization ; microtubule polymerization ; cell population proliferation ; neuron projection development ; regulation of signaling receptor activity ; signal transduction ;
	Sources:Amigo / QuickGO
Orthologs
	50810
	29877
	ENSG00000166503
	ENSMUSG00000025104
	Q9Y3E1
	Q9JMG7
	NM_016073
	NM_013886
	NP_057157
	NP_038914
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 26, 2022

Hepatoma-derived growth factor, related protein 3, also known as HDGFRP3, is a human gene.^[5]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000166503 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025104 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: HDGFRP3 hepatoma-derived growth factor, related protein 3".

Vandegraaff N, Devroe E, Turlure F, et al. (2006). "Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication". Virology. 346 (2): 415–26. doi: 10.1016/j.virol.2005.11.022 . PMID 16337983.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Cherepanov P, Devroe E, Silver PA, Engelman A (2005). "Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase". J. Biol. Chem. 279 (47): 48883–92. doi: 10.1074/jbc.M406307200 . PMID 15371438.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876 . PMID 10810093.
Ikegame K, Yamamoto M, Kishima Y, et al. (2000). "A new member of a hepatoma-derived growth factor gene family can translocate to the nucleus". Biochem. Biophys. Res. Commun. 266 (1): 81–7. doi:10.1006/bbrc.1999.1733. PMID 10581169.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000166503 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025104 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: HDGFRP3 hepatoma-derived growth factor, related protein 3".

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HDGFRP3

Related Research Articles

References

Further reading