HORMAD2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | HORMAD2 , CT46.2, HORMA domain containing 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | MGI: 1923078 HomoloGene: 45130 GeneCards: HORMAD2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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HORMA domain containing 2 is a protein that in humans is encoded by the HORMAD2 gene. [5]
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Phosphatase and actin regulator 1 (PHACTR1) is a protein that in humans is encoded by the PHACTR1 gene on chromosome 6. It is most significantly expressed in the globus pallidus of the brain. PHACTR1 is an actin and protein phosphatase 1 (PP1) binding protein that binds actin and regulates the reorganization of the actin cytoskeleton. This protein has been associated with coronary artery disease and migraines through genome-wide association studies. The PHACTR1 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.
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Netrin-5 (NTN5), also known as netrin-1-like protein, is a protein that in humans is encoded by the NTN5 gene. Netrin-5 is included in the family of secreted laminin-related proteins.