Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, cloning is the process of creating cloned organisms (copies) of cells and of DNA fragments.
A mammoth is any species of the extinct elephantid genus Mammuthus, one of the many genera that make up the order of trunked mammals called proboscideans. The various species of mammoth were commonly equipped with long, curved tusks and, in northern species, a covering of long hair. They lived from the Pliocene epoch into the Holocene at about 4,000 years ago, and various species existed in Africa, Europe, Asia, and North America. They were members of the family Elephantidae, which also contains the two genera of modern elephants and their ancestors. Mammoths are more closely related to living Asian elephants than African elephants.
Extinction is the termination of a kind of organism or of a group of kinds (taxon), usually a species. The moment of extinction is generally considered to be the death of the last individual of the species, although the capacity to breed and recover may have been lost before this point. Because a species' potential range may be very large, determining this moment is difficult, and is usually done retrospectively. This difficulty leads to phenomena such as Lazarus taxa, where a species presumed extinct abruptly "reappears" after a period of apparent absence.
Jean Léopold Nicolas Frédéric, Baron Cuvier, known as Georges Cuvier, was a French naturalist and zoologist, sometimes referred to as the "founding father of paleontology". Cuvier was a major figure in natural sciences research in the early 19th century and was instrumental in establishing the fields of comparative anatomy and paleontology through his work in comparing living animals with fossils.
A mastodon is any proboscidean belonging to the extinct genus Mammut. Mastodons inhabited North and Central America during the late Miocene or late Pliocene up to their extinction at the end of the Pleistocene 10,000 to 11,000 years ago. They lived in herds and were predominantly forest-dwelling animals. They generally had a browsing diet, distinct from that of the contemporary Columbian mammoth, which tended towards grazing.
The steppe bison or steppe wisent is an extinct species of bison that was once found on the mammoth steppe where its range included British Isles, Europe, Central Asia, Northern to Northeastern Asia including Japanese archipelago, Beringia, and central North America, from northwest Canada to Mexico during the Quaternary. This wide distribution is sometimes called the Pleistocene bison belt, compared to the Great bison belt. The radiocarbon dating of a steppe bison skeleton indicates that it was present 5,400 years ago in Alaska. Three chronological subspecies, Bison priscus priscus, Bison priscus mediator, and Bison priscus gigas, have been suggested.
Pleistocene megafauna is the set of large animals that lived on Earth during the Pleistocene epoch. Pleistocene megafauna became extinct during the Quaternary extinction event resulting in substantial changes to ecosystems globally. The role of humans in causing Pleistocene megafaunal extinctions is controversial.
Dwarf elephants are prehistoric members of the order Proboscidea which, through the process of allopatric speciation on islands, evolved much smaller body sizes in comparison with their immediate ancestors. Dwarf elephants are an example of insular dwarfism, the phenomenon whereby large terrestrial vertebrates that colonize islands evolve dwarf forms, a phenomenon attributed to adaptation to resource-poor environments and selection for early maturation and reproduction. Some modern populations of Asian elephants have also undergone size reduction on islands to a lesser degree, resulting in populations of pygmy elephants.
Commercial animal cloning is the cloning of animals for commercial purposes, currently, including livestock, competition camels and horses, pets, medical uses, endangered and extinct animals, as first demonstrated in 1996 for Dolly the sheep.
Beth Alison Shapiro is an American evolutionary molecular biologist. She is a professor in the Department of Ecology and Evolutionary Biology at the University of California, Santa Cruz. Shapiro's work has centered on the analysis of ancient DNA. She was awarded a MacArthur Fellowship in 2009 and a Royal Society University Research Fellowship in 2006.
The Columbian mammoth is an extinct species of mammoth that inhabited the Americas as far north as the Northern United States and as far south as Costa Rica during the Pleistocene epoch. It was one of the last in a line of mammoth species, beginning with Mammuthus subplanifrons in the early Pliocene. DNA studies show that the Columbian mammoth was a hybrid species between woolly mammoths and another lineage descended from steppe mammoths; the hybridization happened more than 420,000 years ago. The pygmy mammoths of the Channel Islands of California evolved from Columbian mammoths. The closest extant relative of the Columbian and other mammoths is the Asian elephant.
Pleistocene rewilding is the advocacy of the reintroduction of extant Pleistocene megafauna, or the close ecological equivalents of extinct megafauna. It is an extension of the conservation practice of rewilding, which involves reintroducing species to areas where they became extinct in recent history.
The woolly mammoth is an extinct species of mammoth that lived during the Pleistocene until its extinction in the Holocene epoch. It was one of the last in a line of mammoth species, beginning with Mammuthus subplanifrons in the early Pliocene. The woolly mammoth began to diverge from the steppe mammoth about 800,000 years ago in East Asia. Its closest extant relative is the Asian elephant. DNA studies show that the Columbian mammoth was a hybrid between woolly mammoths and another lineage descended from steppe mammoths.
Paul Schultz Martin was an American geoscientist at the University of Arizona who developed the theory that the Pleistocene extinction of large mammals worldwide was caused by overhunting by humans. Martin's work bridged the fields of ecology, anthropology, geosciences, and paleontology.
The existence of frozen soft-tissue remains and DNA of woolly mammoths has led to the idea that the species could be recreated by scientific means. In 2003 the pyrenean ibex was briefly revived, giving credence to the idea that the mammoth could be successfully revived. As of today, several methods have been proposed to achieve this goal, including cloning, artificial insemination, and genome editing. The ethics of reviving the animal have been disputed.
De-extinction is the process of generating an organism that either resembles or is an extinct species. There are several ways to carry out the process of de-extinction. Cloning is the most widely proposed method, although genome editing and selective breeding have also been considered. Similar techniques have been applied to certain endangered species, in hopes to boost their genetic diversity. The only method of the three that would provide an animal with the same genetic identity is cloning. There are benefits and malefits to the process of de-extinction ranging from technological advancements to ethical issues.
Molecular paleontology refers to the recovery and analysis of DNA, proteins, carbohydrates, or lipids, and their diagenetic products from ancient human, animal, and plant remains. The field of molecular paleontology has yielded important insights into evolutionary events, species' diasporas, the discovery and characterization of extinct species. loo In shallow time, advancements in the field of molecular paleontology have allowed scientists to pursue evolutionary questions on a genetic level rather than relying on phenotypic variation alone. By applying molecular analytical techniques to DNA in Recent animal remains, one can quantify the level of relatedness between any two organisms for which DNA has been recovered. Using various biotechnological techniques such as DNA isolation, amplification, and sequencing scientists have been able to gain expanded new insights into the divergence and evolutionary history of countless recently extinct organisms. In February 2021, scientists reported, for the first time, the sequencing of DNA from animal remains, a mammoth in this instance, over a million years old, the oldest DNA sequenced to date.
Necrofauna are species that were previously extinct and have been biologically revived or recreated by the process of de-extinction.
Revive & Restore is a California-based nonprofit that works to bring biotechnologies to conservation biology, with the mission to enhance biodiversity through the genetic rescue of endangered and extinct animals.
Colossal Biosciences is a biotechnology and genetic engineering company working to genetically resurrect the woolly mammoth and the Tasmanian tiger. It has claimed to have the first woolly mammoth hybrid calves by 2027 and will reintroduce them to the Arctic tundra habitat to restore the mammoth steppe grasslands and combat climate change. Endangered Asian elephants reportedly would have mammoth traits. Likewise, it plans to launch a thylacine research project to release Tasmanian tiger joeys back to their original Tasmanian and broader Australian habitat after a period of observation in captivity.
