| Hypotelorism | |
|---|---|
| Other names | Ocular hypotelorism, [1] orbital hypotelorism, [1] hypotelorbitism [2] |
| | |
| Hypotelorism as a result of 18p- syndrome | |
Hypotelorism is an abnormally decreased distance between two organs or bodily parts, usually pertaining to the eye sockets (orbits), also known as orbital hypotelorism. [1]
It is often a result of fetal alcohol syndrome (FAS), caused by large alcohol intake in the first month of pregnancy.[ citation needed ]
It can be associated with trisomy 13, which is also known as Patau syndrome, [3] as well as hereditary neuralgic amyotrophy. [4]
It can also be associated with Holoprosencephaly, fragile X syndrome and Prader–Willi syndrome.[ citation needed ]
Metopic synostosis, the early closure of metopic suture during skull development in children, can also cause hypotelorism.[ citation needed ]