INTS11

INTS11
Identifiers
Aliases	INTS11 , CPSF73L, INT11, RC-68, RC68, CPSF3L, cleavage and polyadenylation specific factor 3-like, integrator complex subunit 11
External IDs	OMIM: 611354 MGI: 1919207 HomoloGene: 9894 GeneCards: INTS11
Gene location (Human)
Chr.	Chromosome 1 (human)
End	1,324,687 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	155,973,560 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; canal of the cervix; ; pituitary gland; ; left uterine tube; ; fundus; ; right lobe of thyroid gland; ; anterior pituitary; ; myometrium; ; vagina; ; popliteal artery;
	Top expressed in
	primitive streak; ; medial ganglionic eminence; ; morula; ; spermatocyte; ; lip; ; neural tube; ; thymus; ; somite; ; yolk sac; ; spermatid;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	hydrolase activity ; protein binding ;
Cellular component	blood microparticle ; integrator complex ; nucleoplasm ; cytosol ; nucleus ; cytoplasm ;
Biological process	snRNA processing ; snRNA transcription by RNA polymerase II ; snRNA 3'-end processing ; regulation of RNA splicing ;
	Sources:Amigo / QuickGO
Orthologs
	54973
	71957
	ENSG00000127054
	ENSMUSG00000029034
	Q5TA45
	Q9CWS4
NM_001256456 ; NM_001256460 ; NM_001256462 ; NM_001256463 ; NM_017871 ;
	NM_032179
	NM_028020
	NP_001243385 ; NP_001243389 ; NP_001243391 ; NP_001243392 ; NP_060341 Contents References ; External links ; Further reading ;
	NP_082296
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 12, 2022

Integrator complex subunit 11 is a protein that in humans is encoded by the CPSF3L gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000127054 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029034 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Dominski Z, Yang XC, Purdy M, Wagner EJ, Marzluff WF (Feb 2005). "A CPSF-73 Homologue Is Required for Cell Cycle Progression but Not Cell Growth and Interacts with a Protein Having Features of CPSF-100". Mol Cell Biol. 25 (4): 1489–500. doi:10.1128/MCB.25.4.1489-1500.2005. PMC 548002 . PMID 15684398.
↑ Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi: 10.1016/j.cell.2005.08.019 . PMID 16239144. S2CID 18069461.
↑ "Entrez Gene: CPSF3L cleavage and polyadenylation specific factor 3-like".

External links

Human CPSF3L genome location and CPSF3L gene details page in the UCSC Genome Browser .

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID 16710414.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000127054 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029034 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15684398-5] Dominski Z, Yang XC, Purdy M, Wagner EJ, Marzluff WF (Feb 2005). "A CPSF-73 Homologue Is Required for Cell Cycle Progression but Not Cell Growth and Interacts with a Protein Having Features of CPSF-100". Mol Cell Biol. 25 (4): 1489–500. doi:10.1128/MCB.25.4.1489-1500.2005. PMC 548002 . PMID 15684398.

[pmid16239144-6] Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi: 10.1016/j.cell.2005.08.019 . PMID 16239144. S2CID 18069461.

[entrez-7] "Entrez Gene: CPSF3L cleavage and polyadenylation specific factor 3-like".

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INTS11

Contents

Related Research Articles

References

External links

Further reading