INTS7

INTS7
Identifiers
Aliases	INTS7 , C1orf73, INT7, integrator complex subunit 7
External IDs	OMIM: 611350 MGI: 1924315 HomoloGene: 9136 GeneCards: INTS7
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q32.3 Start 211,940,399 bp [1] End 212,035,557 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 H6 Start 191,307,748 bp [2] End 191,355,800 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence sperm islet of Langerhans right lobe of liver oocyte secondary oocyte rectum endothelial cell stromal cell of endometrium monocyte Top expressed in cumulus cell primitive streak endocardial cushion maxillary prominence hair follicle spermatocyte medial ganglionic eminence ureter medullary collecting duct dermis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component integrator complex chromosome nucleoplasm nucleus cytoplasm nuclear body Biological process cellular response to ionizing radiation DNA damage checkpoint signaling snRNA processing cellular response to DNA damage stimulus snRNA transcription by RNA polymerase II snRNA 3'-end processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25896 77065 Ensembl ENSG00000143493 ENSMUSG00000037461 UniProt Q9NVH2 Q7TQK1 RefSeq (mRNA) NM_001199809 NM_001199811 NM_001199812 NM_015434 NM_178632 NM_001306203 NM_001306204 RefSeq (protein) NP_001186738 NP_001186740 NP_001186741 NP_056249 NP_001293132 NP_001293133 NP_848747 Location (UCSC) Chr 1: 211.94 – 212.04 Mb Chr 1: 191.31 – 191.36 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Integrator complex subunit 7 is a protein that in humans is encoded by the INTS7 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000143493 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000037461 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi: 10.1016/j.cell.2005.08.019 . PMID   16239144. S2CID   18069461.
6. "Entrez Gene: INTS7 integrator complex subunit 7".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.