IPO9

IPO9
Identifiers
Aliases	IPO9 , Imp9, importin 9
External IDs	MGI: 1918944; HomoloGene: 5874; GeneCards: IPO9; OMA:IPO9 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q32.1 Start 201,829,149 bp [1] End 201,884,291 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 E4 Start 135,310,050 bp [2] End 135,358,237 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in nipple ventricular zone pylorus parietal lobe ganglionic eminence ventral tegmental area postcentral gyrus entorhinal cortex cardia inferior ganglion of vagus nerve Top expressed in neural layer of retina hand abdominal wall ventricular zone genital tubercle superior frontal gyrus tail of embryo maxillary prominence mandibular prominence internal carotid artery More reference expression data BioGPS More reference expression data
Gene ontology Molecular function histone binding protein binding nuclear import signal receptor activity Cellular component cytoplasm membrane nucleus nuclear envelope cytosol Biological process protein transport intracellular protein transport protein import into nucleus transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55705 226432 Ensembl ENSG00000198700 ENSMUSG00000041879 UniProt Q96P70 Q91YE6 RefSeq (mRNA) NM_018085 NM_153774 NM_001357575 NM_001357576 NM_001357577 NM_001357578 RefSeq (protein) NP_060555 n/a Location (UCSC) Chr 1: 201.83 – 201.88 Mb Chr 1: 135.31 – 135.36 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Importin-9 is a protein that in humans is encoded by the IPO9 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000198700 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000041879 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Jakel S, Mingot JM, Schwarzmaier P, Hartmann E, Gorlich D (Feb 2002). "Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains". EMBO J. 21 (3): 377–86. doi:10.1093/emboj/21.3.377. PMC   125346 . PMID   11823430.
6. Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O (Jan 2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi: 10.1093/dnares/6.5.329 . PMID   10574461.
7. "Entrez Gene: IPO9 importin 9".

Further reading

• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC   310934 . PMID   11042152.
• Mühlhäusser P, Müller EC, Otto A, Kutay U (2001). "Multiple pathways contribute to nuclear import of core histones". EMBO Rep. 2 (8): 690–6. doi:10.1093/embo-reports/kve168. PMC   1084005 . PMID   11493596.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Lubert EJ, Sarge KD (2003). "Interaction between protein phosphatase 2A and members of the importin beta superfamily". Biochem. Biophys. Res. Commun. 303 (3): 908–13. doi:10.1016/S0006-291X(03)00434-0. PMID   12670497.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID   14743216. S2CID   11683986.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.