This article may need to be rewritten to comply with Wikipedia's quality standards.(September 2022) |
![]() | |
Abbreviation | INGEB |
---|---|
Predecessor | Centre for Genetic Engineering and Biotechnology |
Formation | February 28, 1988 |
Type | Public scientific institution |
Purpose | Research, Education |
Headquarters | Sarajevo |
Location | |
Director | Naris Pojskić, PhD |
Staff | 30 (as of February 2022)[ citation needed ] |
Website | Official website |
Formerly called | Centre for Genetic Engineering and Biotechnology |
Institute for Genetic Engineering and Biotechnology (INGEB) is a Bosnian public research institute, member of Sarajevo University (UNSA), [1] and affiliate center of International Centre for Genetic Engineering and Biotechnology (ICGEB).
ICGEB was established as a special project of the United Nations Industrial Development Organization (UNIDO). [2] [3]
INGEB was founded under the name "Center for Genetic Engineering and Biotechnology", in 1988. INGEB's headquarters are located in Sarajevo.
One of INGEB's most prominent founders was Professor Rifat Hadžiselimović, [4] [5] with the support of the Government of Socialist Republic of Bosnia and Herzegovina, ANUBiH and the biggest B&H economic systems. [6] After the establishment document, INGEB was entrusted with the functions maker, institutional creator and carrier of the overall scientific and professional work in the development of genetic engineering and biotechnology based molecular biology in B&H. [7] [8]
In 1993, by a legal act,[ citation needed ] the Assembly of Republic of Bosnia and Herzegovina, [9] assumed the right of the founder of the institution, at the beginning of the Bosnian War, and later, in 1999, entitled founder of INGEB (as a "public institution that will operate within the University of Sarajevo") took over the Sarajevo Canton. [10] [11] [ clarification needed ]
In INGEB, there are following functional units:
Laboratory for forensic genetics provides scientific approach to analysis of samples of different origin. In this laboratory DNA profiling is routinely done for skeletal remains, blood stains (on different materials), hair, semen, controversial traces on cigarette butts, controversial traces under fingernails, in urine etc.
Expert activities perform in laboratory for forensic genetics include:
In laboratory for forensic genetics scientific projects, supported by the respective ministries and foreign institutions, are implemented or are under realization. The focus of scientific research is directed towards genetic analysis of archaeological skeletal samples, forensic genetic parameters testing of Bosnian population, as well as towards a target oriented expansion of previously initiated population genetic research.
This laboratory represents the organizational segment of the Institute which is dealing with genetic characterisation of DNA of human origin for the purpose of basic and applied research. We use molecular-genetics approach mainly PCR based in investigating the genetic structure.
Main activities of the laboratory comprise research directions:
Other important aspect is participation in higher education programs at University of Sarajevo as well as public engagement in developing molecular-genetics methods for support of medical diagnostics. [13]
The laboratory scope includes wide array of activities mainly focused on the issues of food biosafety and plant biotechnology. It provides qualitative and quantitative analysis of specific DNA sequences in various food matrices, provides advice and correct interpretation of GMO related data to consumers and food safety authority and promotes science based approach to biosafety. In that respect the Laboratory has established communication with JRC-EURL-GMFF and follows the published guidelines. Also, the Laboratory develops new analytical methods, where appropriate, to bridge the gaps in the available methodology.
Research aspect of the Laboratory is mainly focused on endemic and endangered plant species with bioactive potential. Simultaneously with bioactive potential of a species, which is explored in in vitro and in vivo models, molecular markers are employed to evaluate its genetic diversity for the purpose of conservation.
Research activities of the Laboratory for Cytogenetics and Genotoxicology are based on:
Expert activity of the Laboratory for Cytogenetics and Genotoxicology mainly includes chromosome analysis and karyotyping of human samples. The most frequently used tests in research projects of this lab are based on cell culture and include: chromosome aberrations analysis, cytokinesis-block micronucleus cytome assay and sister chromatids exchange assay. Evaluation of cytotoxic and cytostatic potential of various chemical agents includes application of colorimetric method in different cell lines. Research capacities are significantly used for academic education and the realization of final thesis of Sarajevo University students.
Expertises:
Projects:
The Bosna is the third longest river in Bosnia and Herzegovina, and is considered one of the country's three major internal rivers, along with the Neretva and the Vrbas. The other three major rivers of Bosnia and Herzegovina are the Una, to the northwest; the Sava, to the north, and the Drina, to the east. This river is the namesake of Bosnia. The river Bosna flows for 282 kilometers (175 mi).
A polygene is a member of a group of non-epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance, a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core notion of Mendelian inheritance. The term "monozygous" is usually used to refer to a hypothetical gene as it is often difficult to distinguish the effect of an individual gene from the effects of other genes and the environment on a particular phenotype. Advances in statistical methodology and high throughput sequencing are, however, allowing researchers to locate candidate genes for the trait. In the case that such a gene is identified, it is referred to as a quantitative trait locus (QTL). These genes are generally pleiotropic as well. The genes that contribute to type 2 diabetes are thought to be mostly polygenes. In July 2016, scientists reported identifying a set of 355 genes from the last universal common ancestor (LUCA) of all organisms living on Earth.
Kotor Varoš is a town and municipality located in north-western Republika Srpska, an entity of Bosnia and Herzegovina. As of 2013 census, it has a population of 19,710 inhabitants, while the town of Kotor Varoš has a population of 7,330 inhabitants.
The University of Sarajevo is a public university located in Sarajevo, Bosnia and Herzegovina. It is the largest and oldest university in the country, tracing its initial origins to 1537 as an Islamic madrasa.
The Sarajevo Music Academy or Music Academy | University of Sarajevo is a Faculty of Music of University of Sarajevo in Bosnia and Herzegovina.
Šiprage is a settlement municipality in the Bosnia and Herzegovina, Republika Srpska entity, Kotor Varoš Municipality.
The Crkvenica is a Bosnian river. It is a right bank tributary of the Vrbanja River.
Acceleration in human development process is the phenomenon which has been registered in many populations around the world. This applies equally to the growth of certain anthropometric parameters and the speed of reaching sexual maturity. These facts illustrate the results of secular changes in body height and appearance of the first menstruation (menarche).
Academician Rifat Hadžiselimović is a Bosnian geneticist. He was born in Šiprage, Bosnia and Herzegovina on 7 January 1944. In 2013, with over 45 years of service, he was appointed Emeritus. He acts as scientific adviser in Institute for Genetic Engineering and Biotechnology, University of Sarajevo.
Unsuccessful transfer or abortive transfer is any bacterial DNA transfer from donor cells to recipient cells that fails to survive transduction and conjugation. In all cases, the transferred fragment could be diluted during the proliferation phase. Failures in the integration of the transferred DNA in the genetic material of the recipient cells may be due to:
Annulate lamella is one of the cell membrane classes, occurring as a set of parallel elements with double-walled membranes in the same plane/dimension, just as the nuclear envelope. These lamella have pore complexes which are identical to those of the nuclear envelope. It is arranged in highly ordered structure with a regular spacing between themselves.
Salmedin Mesihović is a Bosnian professor of history and archaeology at the Faculty of Philosophy, Department of History, at University of Sarajevo, Bosnia and Herzegovina.
The Academy of Fine Arts Sarajevo is a faculty within the University of Sarajevo in Sarajevo, Bosnia and Herzegovina, dedicated to the fine arts.
Pejo Ćošković, born on 12 April 1952 in Domaljevac near Bosanski Šamac, is Bosnian medievalist and lecturer at the Faculty of Philosophy of the University of Sarajevo, Department of History, in Sarajevo, Bosnia and Herzegovina.
Husnija Kamberović is a Bosnian historian and a professor of modern history at the Faculty of Philosophy, University of Sarajevo, in Sarajevo, Bosnia and Herzegovina.
Ivan Lovrenović is a Bosnia and Herzegovina publicist, writer, historian, essayist, and editor.
Vladimir Boberić (secular name: Vladislav Boberić, Srpska Klarija was the bishop of the Serbian Orthodox Church and professor of music.
The somatic mutation and recombination tests (SMARTs) are in vivo genotoxicity tests performed in Drosophila melanogaster. These fruit fly tests are a short-term test and a non-mammalian approach for in vivo testing of putative genotoxins found in the environment. D. melanogaster has a short lifespan, which allows for fast reproductive cycles and high-throughput genotoxicity testing. D. melanogaster also has around 75% functional orthologs of human disease-related genes, making it an attractive in vivo model for human research. The tests identify loss of heterozygosity for the specified genetic markers in heterozygous or trans-heterozygous adults using phenotypically observable genetic markers in adult tissues. Although diverse events like point mutations/deletions, nondisjunction, and homologous mitotic recombination might theoretically cause this loss of heterozygozity, nondisjunction processes are generally not relevant for most of the examined chemicals. SMARTs are two different tests that use the same genetic foundation, but target different adult tissues and are named accordingly: the wing-spot test and the eye-spot test.
The Center for Demographic Genetics of the Academy of Sciences and Arts of Bosnia and Herzegovina, was established on July 15, 2020 at the formal proposal of the Department of Natural and Mathematical Sciences, which was represented by a wider circle of interested institutions and individuals in the field of natural and social sciences.
Boris Nilević was a Bosnian historian of the middle-ages and early modern era.