Obaid Siddiqi FRS was an Indian National Research Professor and the Founder-Director of the Tata Institute of Fundamental Research (TIFR) National Center for Biological Sciences. He made seminal contributions to the field of behavioural neurogenetics using the genetics and neurobiology of Drosophila.
Psychiatric genetics is a subfield of behavioral neurogenetics and behavioral genetics which studies the role of genetics in the development of mental disorders. The basic principle behind psychiatric genetics is that genetic polymorphisms are part of the causation of psychiatric disorders.
Genes, Brain and Behavior is a peer-reviewed scientific journal covering research in the fields of behavioral, neural, and psychiatric genetics. It is published by Wiley-Blackwell on behalf of the International Behavioural and Neural Genetics Society. The journal was established in 2002 as a quarterly and is currently published monthly. G2B is a hybrid open access journal, but two years after publication all content is available for free online.
Hans van Abeelen was the first Dutch behaviour geneticist. He obtained his M.Sc from the University of Groningen and his Ph.D. from the Catholic University of Nijmegen in 1965, where he stayed for the rest of his career as "wetenschappelijk hoofdmedewerker". He was a founding member of the Behavior Genetics Association and was a member-at-large of its executive committee from 1984 till 1987. He also served on the editorial board of its journal, Behavior Genetics, from its creation in 1971 to 1992. Van Abeelen took early retirement in 1991, but nevertheless became one of the founding members of the International Behavioural and Neural Genetics Society. Over the span of his career, he published 64 articles and book chapters and edited a book, The Genetics of Behaviour, which was an early overview of European behaviour genetics.
Robert T. Gerlai is a Canadian behaviour geneticist.
The International Behavioral Neuroscience Society (IBNS), was founded in 1992. The goal of the IBNS is to "encourage research and education in the field of behavioral neuroscience". Its current president is Mikhail Pletnikov. Brain Research Bulletin, Neuroscience and Biobehavioral Reviews, and Physiology and Behavior are official journals of the IBNS.
Neurogenetics studies the role of genetics in the development and function of the nervous system. It considers neural characteristics as phenotypes, and is mainly based on the observation that the nervous systems of individuals, even of those belonging to the same species, may not be identical. As the name implies, it draws aspects from both the studies of neuroscience and genetics, focusing in particular how the genetic code an organism carries affects its expressed traits. Mutations in this genetic sequence can have a wide range of effects on the quality of life of the individual. Neurological diseases, behavior and personality are all studied in the context of neurogenetics. The field of neurogenetics emerged in the mid to late 20th century with advances closely following advancements made in available technology. Currently, neurogenetics is the center of much research utilizing cutting edge techniques.
Ursula Bellugi was an American cognitive neuroscientist. She was a Distinguished Professor Emerita and director of the Laboratory for Cognitive Neuroscience at the Salk Institute in La Jolla, California. She is known for research on the neurological bases of American Sign Language and language representation in people with Williams Syndrome.
Ambidirectional dominance occurs in a situation where multiple genes influence a phenotype and dominance is in different directions depending on the gene. For example, for gene A increased height is dominant, while for gene B decreased height is dominant. The opposite situation, where all genes show dominance in the same direction, is called directional dominance. In the same example, for both genes A and B increased height is dominant. According to Broadhurst, ambidirectional dominance is the result of stabilising selection in the evolutionary past. Ambidirectional dominance has been found for exploratory behaviours in mice and paradise fish.
Behavioural genetics, also referred to as behaviour genetics, is a field of scientific research that uses genetic methods to investigate the nature and origins of individual differences in behaviour. While the name "behavioural genetics" connotes a focus on genetic influences, the field broadly investigates the extent to which genetic and environmental factors influence individual differences, and the development of research designs that can remove the confounding of genes and environment. Behavioural genetics was founded as a scientific discipline by Francis Galton in the late 19th century, only to be discredited through association with eugenics movements before and during World War II. In the latter half of the 20th century, the field saw renewed prominence with research on inheritance of behaviour and mental illness in humans, as well as research on genetically informative model organisms through selective breeding and crosses. In the late 20th and early 21st centuries, technological advances in molecular genetics made it possible to measure and modify the genome directly. This led to major advances in model organism research and in human studies, leading to new scientific discoveries.
Cultural neuroscience is a field of research that focuses on the interrelation between a human's cultural environment and neurobiological systems. The field particularly incorporates ideas and perspectives from related domains like anthropology, psychology, and cognitive neuroscience to study sociocultural influences on human behaviors. Such impacts on behavior are often measured using various neuroimaging methods, through which cross-cultural variability in neural activity can be examined.
Wim E. Crusio is a Dutch behavioral neurogeneticist and a directeur de recherche with the French National Centre for Scientific Research in Talence, France.
Jacqueline N. Crawley is an American behavioral neuroscientist and an expert on rodent behavioral analysis. Since July 2012, she is the Robert E. Chason Chair in Translational Research in the MIND Institute and professor of psychiatry and behavioral sciences at the University of California, Davis School of Medicine in Sacramento. Previously, from 1983–2012, she was chief of the Laboratory of Behavioral Neuroscience in the intramural program of the National Institute of Mental Health. Her translational research program focuses on testing hypotheses about the genetic causes of autism spectrum disorders and discovering treatments for the diagnostic symptoms of autism, using mouse models. She has published more than 275 peer-reviewed articles in scientific journals and 110 review articles and book chapters. According to Scopus, her works have been cited over 36,000 times, giving her an h-index of 99. She has co-edited 4 books and is the author of What's Wrong With my Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, which was very well received.
Justin S. Rhodes is an American neuroscientist and a professor in the Department of Psychology at the University of Illinois at Urbana-Champaign. He is affiliated with the Neuroscience Program, Program of Ecology, Evolution, & Conservation Biology, the Carl R. Woese Institute for Genomic Biology, and the Neurotech group at Beckman Institute for Advanced Science and Technology. After receiving a Bachelor of Science in biology at Stanford University, Rhodes obtained a PhD in zoology in 2002 from University of Wisconsin–Madison, under the supervision of Theodore Garland, Jr. After completing a postdoctoral fellowship at Oregon Health & Science University, he held a position as an instructor at Lewis & Clark College for a year before accepting a full-time faculty position in 2005 in the biological division of the Department of Psychology at the University of Illinois. His lab investigates a broad array of topics in the field of neuroscience with particular emphasis in exercise-induced hippocampal neurogenesis, neural circuitry involved in addictive behaviors, and brain plasticity in clownfish.
Developed by Calvin S. Hall, the open field test is an experimental test used to assay general locomotor activity levels, anxiety, and willingness to explore in animals in scientific research. However, the extent to which behavior in the open field measures anxiety is controversial. The open field test can be used to assess memory by evaluating the ability of the animal to recognize a stimuli or object. Another animal test that is used to assess memory using that same concept is the novel object recognition test.
A knockout mouse, or knock-out mouse, is a genetically modified mouse in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA. They are important animal models for studying the role of genes which have been sequenced but whose functions have not been determined. By causing a specific gene to be inactive in the mouse, and observing any differences from normal behaviour or physiology, researchers can infer its probable function.
Douglas Leon Wahlsten is a Canadian neuroscientist, psychologist, and behavior geneticist. He is a professor emeritus of psychology at the University of Alberta. As of 2011, he was also a visiting professor at the University of North Carolina at Greensboro in North Carolina, United States. He is known for his laboratory research on the behavior of mice, and for his theoretical writings on a wide range of other topics. His laboratory research has included studies of the effects of different laboratory environments and experimenter characteristics on the results of mouse studies. He and his colleagues have also developed an altered form of the rotarod performance test involving wrapping sandpaper around the rod, to reduce the ability of mice to grip the rod and ride around on it. He has criticized some of his fellow behavior geneticists for trying to separate the effects of genes and the environment on human intelligence, an endeavor he considers futile. He also met and became friends with Leilani Muir, later helping to edit her autobiography, A Whisper Past. He was the president of the International Behavioural and Neural Genetics Society from 2000 to 2001.
Pierre L. Roubertoux is a French behavioral geneticist.
Marla B. Sokolowski is a University Professor in the Departments of Ecology and Evolutionary Biology at the University of Toronto. Sokolowski is a scientist whose work is widely considered to be groundbreaking, foundational for a variety of fields, and instrumental in refutations of genetic determinism, and has, according to the Royal Society of Canada, "permanently changed the way we frame questions about individual differences in behaviour". Sokolowski's comprehensive study of the fruit fly and other animal systems, including humans, has shaped fundamental concepts in behavioural evolution, plasticity, and genetic pleiotropy. Specifically, Sokolowski is best known for her discovery of the foraging gene. Sokolowski was the 2020 recipient of the Flavelle Medal. Sokolowski is only one of two women to ever win the award- the other being Margaret Newton in 1948.
Karla Renea Kaun (1979) is a Canadian behavioral neurogeneticist and the Robert and Nancy Carney Associate Professor of Neuroscience at Brown University. She studies addiction using fruit flies, as a model. Kaun is currently president of the International Behavioural and Neural Genetics Society (IBANGS).
