Intraflagellar transport protein 46 homolog

IFT46
Identifiers
Aliases	IFT46 , C11orf2, C11orf60, CFAP32, intraflagellar transport 46
External IDs	MGI: 1923818; HomoloGene: 10596; GeneCards: IFT46; OMA:IFT46 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q23.3 Start 118,544,528 bp [1] End 118,572,970 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A5.2 Start 44,679,205 bp [2] End 44,704,744 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube bronchial epithelial cell olfactory zone of nasal mucosa Achilles tendon anterior pituitary islet of Langerhans cerebellar hemisphere right hemisphere of cerebellum mucosa of paranasal sinus nucleus accumbens Top expressed in spermatocyte genital tubercle ventricular zone spermatid saccule dentate gyrus of hippocampal formation granule cell medial ganglionic eminence superior frontal gyrus otic placode primary visual cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein C-terminus binding molecular function protein binding Cellular component cytoplasm intraciliary transport particle B ciliary basal body centrosome cell projection ciliary tip cytoskeleton cilium motile cilium Biological process smoothened signaling pathway protein stabilization intraciliary transport intraciliary transport involved in cilium assembly cilium assembly biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56912 76568 Ensembl ENSG00000118096 ENSMUSG00000002031 UniProt Q9NQC8 Q9DB07 RefSeq (mRNA) NM_001168618 NM_020153 NM_023831 RefSeq (protein) NP_001162089 NP_064538 NP_076320 Location (UCSC) Chr 11: 118.54 – 118.57 Mb Chr 9: 44.68 – 44.7 Mb PubMed search [3] [4]
Wikidata
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Intraflagellar transport protein 46 homolog is a protein that in humans is encoded by the IFT46 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000118096 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000002031 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. O'Brien KP, Tapia-Paez I, Stahle-Backdahl M, Kedra D, Dumanski JP (Jul 2000). "Characterization of five novel human genes in the 11q13-q22 region". Biochem Biophys Res Commun. 273 (1): 90–4. doi:10.1006/bbrc.2000.2910. PMID   10873569.
6. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
7. "Entrez Gene: C11orf60 chromosome 11 open reading frame 60".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.