Related Research Articles
Anticonvulsants are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of bipolar disorder and borderline personality disorder,since many seem to act as mood stabilizers,and for the treatment of neuropathic pain. Anticonvulsants suppress the excessive rapid firing of neurons during seizures. Anticonvulsants also prevent the spread of the seizure within the brain.
Lamotrigine,sold under the brand name Lamictal among others,is a medication used to treat epilepsy and stabilize mood in bipolar disorder. For epilepsy,this includes focal seizures,tonic-clonic seizures,and seizures in Lennox-Gastaut syndrome. In bipolar disorder,lamotrigine has not been shown to reliably treat acute depression;but for patients with bipolar disorder who are not currently symptomatic,it appears to be effective in reducing the risk of future episodes of depression.
Levetiracetam,sold under the brand name Keppra among others,is a medication used to treat epilepsy. It is used for partial-onset,myoclonic,or tonic–clonic seizures and is taken either by mouth as an immediate or extended release formulation or by injection into a vein.
Ruben Kuzniecky is an Argentine neurologist who is Vice-chair academic affairs and professor of neurology at Northwell Health specializing in the field of epilepsy,epilepsy surgery and neuro-imaging.
Vigabatrin,sold under the brand name Sabril,is a medication used to treat epilepsy. It became available as a generic medication in 2019.
Felbamate is an anticonvulsant used in the treatment of epilepsy. It is used to treat partial seizures in adults and partial and generalized seizures associated with Lennox–Gastaut syndrome in children. However,an increased risk of potentially fatal aplastic anemia and/or liver failure limit the drug's usage to severe refractory epilepsy.
Tocilizumab,sold under the brand name Actemra among others,is an immunosuppressive drug,used for the treatment of rheumatoid arthritis,systemic juvenile idiopathic arthritis,a severe form of arthritis in children,and COVID‑19. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases,such as autoimmune diseases,multiple myeloma and prostate cancer. Tocilizumab was jointly developed by Osaka University and Chugai,and was licensed in 2003 by Hoffmann-La Roche.
Eva Lucille Feldman,M.D.,Ph.D.,F.A.A.N.,F.A.N.A. is an American physician-scientist and one of the world’s leading authorities on neurodegenerative disease. Currently,she serves as the Russell N. DeJong Professor of Neurology at the University of Michigan,as well as Director of the NeuroNetwork for Emerging Therapies and ALS Center of Excellence at Michigan Medicine. She was also recently named the James W. Albers Distinguished University Professor of Neurology,the highest faculty honor at the university.
Lacosamide,sold under the brand name Vimpat among others,is a medication used for the treatment of partial-onset seizures and primary generalized tonic-clonic seizures. It is used by mouth or intravenously.
Remacemide is a drug which acts as a low-affinity NMDA antagonist with sodium channel blocking properties. It has been studied for the treatment of acute ischemic stroke,epilepsy,Huntington's disease,and Parkinson's disease.
NYU Langone Health is an academic medical center located in New York City,New York,United States. The health system consists of NYU Grossman School of Medicine and NYU Long Island School of Medicine,both part of New York University (NYU),and more than 300 locations throughout the New York metropolitan area,including six inpatient facilities:Tisch Hospital,Kimmel Pavilion,NYU Langone Orthopedic Hospital,Hassenfeld Children's Hospital,NYU Langone Hospital –Brooklyn and NYU Langone Hospital –Long Island. It is also home to Rusk Rehabilitation. NYU Langone Health is one of the largest healthcare systems in the Northeast,with more than 46,000 employees.
Orrin Devinsky is an American neurologist who is the Director of the NYU Comprehensive Epilepsy Center and the Saint Barnabas Institute of Neurology and Neurosurgery (INN). He is also a professor of Neurology,Neurosurgery,and Psychiatry at NYU Langone School of Medicine. Devinsky specializes in epilepsy and behavioral neurology.
David Charles is an American neurologist,professor and vice-chair of neurology,and the medical director of Telehealth at Vanderbilt University Medical Center.
James O. McNamara is an American neurologist and neuroscientist,known for his research of epileptogenesis,the process underlying development and progression of epilepsy. He is the Duke School of Medicine Professor of Neuroscience in the Departments of Neurobiology,Neurology,and Pharmacology and Cancer Biology at Duke University. He served as chair of the Department of Neurobiology at Duke from 2002 to 2011
Luciana Borio is a Brazilian-American infectious disease physician and public health administrator. She is a vice president at In-Q-Tel. She previously served as director for Medical and Biodefense Preparedness at the National Security Council,acting chief scientist of the U.S. Food and Drug Administration (FDA),assistant commissioner for counterterrorism policy of the FDA,and director of FDA's Office of Counterterrorism and Emerging Threats. She is known for her work advancing clinical trials,the development of medical countermeasures for health emergencies,and the public health responses to Ebola and Zika outbreaks.
Charlotte's Web is a brand of high-cannabidiol (CBD),low-tetrahydrocannabinol (THC) products derived from industrial hemp and marketed as dietary supplements and cosmetics under federal law of the United States. It is produced by Charlotte's Web,Inc. in Colorado. Hemp-derived products do not induce the psychoactive "high" typically associated with recreational marijuana strains that are high in THC. Charlotte's Web hemp-derived products contain less than 0.3% THC.
John Mark Freeman was an American pediatric neurologist specializing in epilepsy. He is known for bringing two long-abandoned treatments for pediatric epilepsy back into popular use. One,the ketogenic diet,is a carefully managed,low-carbohydrate high-fat diet plan that reduces the incidence of seizures in children during and after its use,and the other,the hemispherectomy,is a drastic surgical procedure in which part or all of one highly seizure-prone hemisphere of the brain is removed to alleviate severe epilepsy.
Satralizumab,sold under the brand name Enspryng,is a humanized monoclonal antibody medication that is used for the treatment of neuromyelitis optica spectrum disorder (NMOSD),a rare autoimmune disease. The drug is being developed by Chugai Pharmaceutical,a subsidiary of Roche.
JoséEnrique Cavazos is a Mexican-American physician-scientist. He is a professor and assistant dean of the MD/PhD program at the University of Texas Health Science Center at San Antonio.
Ayana Jordan is an American addiction psychiatrist and immunopathologist. She researches treatments for substance use disorders in marginalized communities. She is the Barbara Wilson Associate Professor of Psychiatry at NYU Langone Health and was a professor at Yale School of Medicine. She served as an attending psychiatrist in the Yale University Department of Psychiatry. She was elected to the Board of Trustees of the American Psychiatric Association in 2018. She attended Hampton University and received her MD and PhD from the Albert Einstein College of Medicine.
References
- ↑ "Jacqueline A. French, MD". NYU Langone Health. Retrieved January 17, 2023.
- 1 2 3 Nierengarten, Mary Beth (September 2008). "Jacqueline French: Pioneering trial protocols for epilepsy" (PDF). The Lancet . 7 (9): 774. doi:10.1016/S1474-4422(08)70185-6. PMID 18703002. S2CID 43560728 . Retrieved January 17, 2023.
- 1 2 3 "Jacqueline A. French, MD, Named First Vice President of American Epilepsy Society". Newswire. December 5, 2011. Retrieved January 25, 2023.
- ↑ "Awardees". American Epilepsy Society. Retrieved January 25, 2023.
- 1 2 "Meet Dr. Jacqueline French". Epilepsy Foundation. Archived from the original on May 20, 2022. Retrieved January 25, 2023.
- ↑ "FDA Accepts Historical Controls for Epilepsy Monotherapy Studies". Science Daily. July 20, 2010. Retrieved January 25, 2023.
- ↑ "Ambassador for Epilepsy Award 2009". International League Against Epilepsy . Retrieved January 25, 2023.
- ↑ "New drug may reduce seizures in epilepsy". Science Daily. April 14, 2011. Retrieved January 25, 2023.
- ↑ "Jacqueline A. French, MD, Named President of American Epilepsy Society". Newswire. December 3, 2012. Retrieved January 25, 2023.
- ↑ "Jacqueline A. French, M.D. Receives the Epilepsy Foundation 2013 Hero of Epilepsy Award". Epilepsy Foundation. April 22, 2013. Retrieved January 25, 2023.
- ↑ "Epilepsy Foundation Names Jacqueline A. French, MD, as New Chief Scientific Officer". Epilepsy Foundation. April 20, 2015. Retrieved January 25, 2023.
- ↑ "New Guidelines Inform Clinicians How to Treat a First Seizure". NYU Langone Medical Center. April 20, 2015. Retrieved January 25, 2023.
- ↑ "Jacqueline A. French, MD, to Be Honored for Lifetime Accomplishments in Epilepsy at the American Epilepsy Society's Annual Meeting". American Epilepsy Society. November 27, 2017. Retrieved January 25, 2023.
- ↑ "Jacqueline French, MD, Joins the Board of the American Brain Foundation" (PDF). American Brain Foundation. January 24, 2020. Retrieved January 25, 2023.
- ↑ Dugan, P.; Carroll, E.; Thorpe, J.; Jette, N.; Agarwal, P.; Ashby, S.; Hanna, J.; French, J.; Devinsky, O.; Sen, A.; COVID-19 Epilepsy COV-E Study Group (August 5, 2022). "Impact of the COVID-19 pandemic on people with epilepsy: findings from the US arm of the COV-E study". Epilepsia Open. 7 (4): 645–656. doi:10.1002/epi4.12637. PMC 9537888 . PMID 35929180.
- ↑ "Nearly Two Dozen NYU Professors Among the World's Most Cited Researchers". New York University. November 15, 2022. Retrieved January 25, 2023.