Neuroscience is the scientific study of the nervous system, its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences.
Cognitive neuroscience is the scientific field that is concerned with the study of the biological processes and aspects that underlie cognition, with a specific focus on the neural connections in the brain which are involved in mental processes. It addresses the questions of how cognitive activities are affected or controlled by neural circuits in the brain. Cognitive neuroscience is a branch of both neuroscience and psychology, overlapping with disciplines such as behavioral neuroscience, cognitive psychology, physiological psychology and affective neuroscience. Cognitive neuroscience relies upon theories in cognitive science coupled with evidence from neurobiology, and computational modeling.
Computational neuroscience is a branch of neuroscience which employs mathematics, computer science, theoretical analysis and abstractions of the brain to understand the principles that govern the development, structure, physiology and cognitive abilities of the nervous system.
Terrence Joseph Sejnowski is the Francis Crick Professor at the Salk Institute for Biological Studies where he directs the Computational Neurobiology Laboratory and is the director of the Crick-Jacobs center for theoretical and computational biology. He has performed pioneering research in neural networks and computational neuroscience.
The Conference and Workshop on Neural Information Processing Systems is a machine learning and computational neuroscience conference held every December. The conference is currently a double-track meeting that includes invited talks as well as oral and poster presentations of refereed papers, followed by parallel-track workshops that up to 2013 were held at ski resorts.
Neuroinformatics is the field that combines informatics and neuroscience. Neuroinformatics is related with neuroscience data and information processing by artificial neural networks. There are three main directions where neuroinformatics has to be applied:
Spiking neural networks (SNNs) are artificial neural networks that more closely mimic natural neural networks. In addition to neuronal and synaptic state, SNNs incorporate the concept of time into their operating model. The idea is that neurons in the SNN do not transmit information at each propagation cycle, but rather transmit information only when a membrane potential—an intrinsic quality of the neuron related to its membrane electrical charge—reaches a specific value, called the threshold. When the membrane potential reaches the threshold, the neuron fires, and generates a signal that travels to other neurons which, in turn, increase or decrease their potentials in response to this signal. A neuron model that fires at the moment of threshold crossing is also called a spiking neuron model.
Whyville is an educational Internet site geared towards children aged 8–14, founded and managed by Numedeon Inc. Whyville engages its uses in learning about a broad range of topics, including science, business, art and geography. Whyville's users (Whyvillians) engage in virtual world simulation based games and role play sponsored by a wide range of governmental, non-profit, and corporate entities. In 2009, the website had a registered base of more than 7 million users.
GENESIS is a simulation environment for constructing realistic models of neurobiological systems at many levels of scale including: sub-cellular processes, individual neurons, networks of neurons, and neuronal systems. These simulations are “computer-based implementations of models whose primary objective is to capture what is known of the anatomical structure and physiological characteristics of the neural system of interest”. GENESIS is intended to quantify the physical framework of the nervous system in a way that allows for easy understanding of the physical structure of the nerves in question. “At present only GENESIS allows parallelized modeling of single neurons and networks on multiple-instruction-multiple-data parallel computers.” Development of GENESIS software spread from its home at Caltech to labs at the University of Texas at San Antonio, the University of Antwerp, the National Centre for Biological Sciences in Bangalore, the University of Colorado, the Pittsburgh Supercomputing Center, the San Diego Supercomputer Center, and Emory University.
Numedeon, Inc. is a privately held company based in Pasadena, California, that since 1999 has been developing immersive online digital learning technology. Best known for creating the children's educational web site "Whyville", Numedeon has also developed a number of other immersive online learning environments for other demographics and purposes. Numedeon was founded by Dr. James M. Bower and several of his students and colleagues at the California Institute of Technology.
Randall Charles O'Reilly is a professor of psychology and computer science at the Center for Neuroscience at the University of California, Davis. His lab moved to UC Davis from the University of Colorado at Boulder in 2019.
Mark A. Gluck is a professor of neuroscience at Rutgers–Newark in New Jersey, director of the Rutgers Memory Disorders Project, and publisher of the public health newsletter, Memory Loss and the Brain. He works at the interface between neuroscience, psychology, and computer science, studying the neural bases of learning and memory. He is the co-author of Gateway to Memory: An Introduction to Neural Network Models of the Hippocampus and an undergraduate textbook Learning and Memory: From Brain to Behavior.
The Computation and Neural Systems (CNS) program was established at the California Institute of Technology in 1986 with the goal of training Ph.D. students interested in exploring the relationship between the structure of neuron-like circuits/networks and the computations performed in such systems, whether natural or synthetic. The program was designed to foster the exchange of ideas and collaboration among engineers, neuroscientists, and theoreticians.
AnimatLab is an open-source neuromechanical simulation tool that allows authors to easily build and test biomechanical models and the neural networks that control them to produce behaviors. Users can construct neural models of varied level of details, 3D mechanical models of triangle meshes, and use muscles, motors, receptive fields, stretch sensors and other transducers to interface the two systems. Experiments can be run in which various stimuli are applied and data is recorded, making it a useful tool for computational neuroscience. The software can also be used to model biomimetic robotic systems.
The Bernstein Network is a research network in the field of computational neuroscience; this field brings together experimental approaches in neurobiology with theoretical models and computer simulations. It unites different scientific disciplines, such as physics, biology, mathematics, medical science, psychology, computer science, engineering and philosophy in the endeavor to understand how the brain functions. The close combination of neurobiological experiments with theoretical models and computer simulations allows scientists of the Bernstein Network to pursue innovative approaches with regard to one of the most complex structures nature has created in the course of evolution: the natural brain.
Newton Howard is a brain and cognitive scientist, the former founder and director of the MIT Mind Machine Project at the Massachusetts Institute of Technology (MIT). He is a professor of computational neurology and functional neurosurgery at Georgetown University. He was a professor of at the University of Oxford, where he directed the Oxford Computational Neuroscience Laboratory. He is also the director of MIT's Synthetic Intelligence Lab, the founder of the Center for Advanced Defense Studies and the chairman of the Brain Sciences Foundation. Professor Howard is also a senior fellow at the John Radcliffe Hospital at Oxford, a senior scientist at INSERM in Paris and a P.A.H. at the CHU Hospital in Martinique.
Haim Sompolinsky, is the William N. Skirball Professor of Neuroscience at the Edmond and Lily Safra Center for Brain Sciences, and a professor of physics at the Racah Institute of Physics at The Hebrew University of Jerusalem, Israel. He is also a visiting professor in the Center of Brain Science at Harvard University and the director of Harvard's Swartz Program in Theoretical Neuroscience. He is widely regarded as one of the leaders of theoretical neuroscience.
Upinder Singh Bhalla is an Indian computational neuroscientist, academic and a professor at National Centre for Biological Sciences of the Tata Institute of Fundamental Research. He is known for his studies on neuronal and synaptic signalling in memory and olfactory coding using computational and experimental methods and is an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2007, for his contributions to biological sciences. The Infosys Science Foundation awarded him the Infosys Prize 2017 in Life Sciences for his pioneering contributions to the understanding of the brain's computational machinery.
Tim P. Vogels is a professor of theoretical neuroscience and research leader at the Institute of Science and Technology Austria. He is primarily known for his scholarly contributions to the study of neuronal plasticity related to learning and memory in the brain.
Ila Fiete is an Indian–American physicist and computational neuroscientist as well as a Professor in the Department of Brain and Cognitive Sciences within the McGovern Institute for Brain Research at the Massachusetts Institute of Technology. Fiete builds theoretical models and analyses neural data and to uncover how neural circuits perform computations and how the brain represents and manipulates information involved in memory and reasoning.
