Upinder Singh Bhalla

Last updated

Upinder Singh Bhalla
Upinder Singh Bhalla.jpg
Born (1963-06-21) 21 June 1963 (age 61)
Nationality Indian
Alma mater
Known forComputational and experimental studies on neuronal and Synaptic signalling
Awards
Scientific career
Fields
Institutions
Doctoral advisor

Upinder Singh Bhalla (born 1963) is an Indian computational neuroscientist, academic and a professor at National Centre for Biological Sciences of the Tata Institute of Fundamental Research. [1] He is known for his studies on neuronal and synaptic signalling in memory and olfactory coding using computational and experimental methods [2] and is an elected fellow of the Indian Academy of Sciences [3] and the Indian National Science Academy. [4] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2007, for his contributions to biological sciences. [5] The Infosys Science Foundation [6] awarded him the Infosys Prize 2017 in Life Sciences for his pioneering contributions to the understanding of the brain's computational machinery. [7]

Contents

Biography

Upinder S. Bhalla, born in the Indian capital of Delhi to an academic couple who were professors at Jawaharlal Nehru University, enrolled himself at the Indian Institute of Technology, Kanpur for an integrated master's program but discontinued his studies at IITK after one year to join Cambridge University from where he graduated in natural sciences. [1] Subsequently, he secured a PhD under the guidance of James M. Bower from California Institute of Technology in 1993 and did his post doctoral studies at the laboratory of Ravi Iyengar at Mount Sinai School of Medicine. [8] Returning to India, he joined National Centre for Biological Sciences, a Bengaluru-based biological research centre of Tata Institute of Fundamental Research where he became an assistant professor in 2002 and an associate professor in 2003, before becoming a professor in 2012. [9] He heads a laboratory at NCBS where he hosts a number of research associates, post-doctoral fellows and doctoral students who are involved in the research on Memory and Plasticity through computational and experimental methods. [10]

Legacy

Bhalla's research has widened our understanding of memory functioning and he has contributed to understanding the neural coding of olfactory information. [11] His team at NCBS uses optogenetic techniques for monitoring brain cell activity and uses light to stimulate the activity. [12] Bhalla and his colleagues developed MOOSE (Multiscale Object-Oriented Simulation Environment), a simulation tool which helps build computer models of molecules and molecular networks. [13] He has mentored several research scholars in their doctoral and post-doctoral studies [8] [14] and is a member of the council of the Indian National Science Academy. [15]

Awards and honours

Bhalla received the Shanti Swarup Bhatnagar Prize of the Council of Scientific and Industrial Research in 2007 for his contributions to Biological Sciences. [5] The same year, the Indian Academy of Sciences elected him as their fellow. [3] Three years later, he also became an elected fellow of the Indian National Science Academy. [4] In 2017, he received the Infosys Prize in Life Sciences for the excellent work he has been doing for the last two decades which is now not only nationally but internationally recognised as one of the fundamental ways of how we study the role of olfaction in behaviour. [16]

Selected bibliography

See also

Notes

    Related Research Articles

    Amit Prakash Sharma is an Indian parasitologist and Former Director of National Institute of Malaria Research, New Delhi. He is known for his studies on the disease of malaria and is an elected fellow of the Indian Academy of Sciences, Indian National Science Academy, The World Academy of Sciences and the National Academy of Sciences, India. He has been awarded the Shanti Swarup Bhatnagar Award in Biological Sciences, JC Bose Fellowship, Ranbaxy Science Research Award, Infosys Science Award in Biological Sciences, Om Prakash Bhasin Award in Biological Sciences and Lakshmipat Singhania- IIM Lucknow National Leadership Award.

    Satyajit Mayor (born 1963) is an Indian biologist. He serves as director of the National Centre for Biological Sciences, Bangalore. Mayor is the former director of the Institute for Stem Cell Biology and Regenerative Medicine (inStem) at Bangalore, which has a focus on the study of stem cell and regenerative biology.

    Yamuna Krishnan is a professor at the Department of Chemistry, University of Chicago, where she has worked since August 2014. She was born to P.T. Krishnan and Mini in Parappanangadi, in the Malappuram district of Kerala, India. She was earlier a Reader in National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India. Krishnan won the Shanti Swarup Bhatnagar Prize for science and technology, the highest science award in India in the year 2013 in the Chemical Science category.

    Roop Mallik is an Indian biophysicist who works on nanoscale molecular motor proteins that transport material such as viruses, mitochondria, endosomes etc. inside living cells. The motors, such as kinesin and dynein generate forces of pico-newton order to carry our various cellular processes namely cell division, vesicular transport, endocytosis, molecular tethering etc. His lab is working to understand how motor proteins help in degradation and clearance of pathogens, and also how these motors work inside the liver to maintain systemic lipid homeostasis in the animal. Mallik is currently a professor at the Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay.

    Sanghamitra Bandyopadhyay is an Indian scientist specializing in computational biology. A professor at the Indian Statistical Institute, Kolkata, she is a Shanti Swarup Bhatnagar Prize winner in Engineering Science for 2010, IInfosys Prize 2017 laureate in the Engineering and Computer Science category and TWAS Prize winner for Engineering Sciences in 2018. Her research is mainly in the areas of evolutionary computation, pattern recognition, machine learning and bioinformatics. Since 1 August 2015, she has been the Director of the Indian Statistical Institute, and she would oversee the functioning of all five centres of Indian Statistical Institute located at Kolkata, Bangalore, Delhi, Chennai, and Tezpur besides several other Statistical Quality Control & Operation Research Units spread across India. She is the first woman Director of the Indian Statistical Institute. Currently she is on the Prime Ministers' Science, Technology and Innovation Advisory Council. In 2022 she was given the Padma Shri award for Science and Engineering by the Government of India.

    Guru Prakash Dutta was an Indian cell biologist and immunologist, known for his contributions to the subjects of Experimental protozoology and Immunology. His researches are reported to have assisted in the development of a number of anti-malarial drugs. He was an elected fellow of the Indian National Science Academy, National Academy of Sciences, India and Indian Society of Parasitology. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1976, for his contributions to biological sciences.

    Bhabatarak Bhattacharyya, popularly known as Bablu Bhattacharyya, is an Indian structural biologist, biochemist and academic, known for his studies on the colchicine-tubulin interaction. He is a former professor and the head of the department of biochemistry at the Bose Institute, Kolkata and an elected fellow of the Indian Academy of Sciences, Indian National Science Academy, National Academy of Sciences, India and The World Academy of Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1988, for his contributions to biological sciences.

    Ramakrishnan Nagaraj is an Indian biochemist, molecular biologist and the leader of a team of scientists working in the field of peptide biochemistry at Centre for Cellular and Molecular Biology (CCMB). He is known for his studies on hemolytic and antibacterial properties in synthetic analogs of bacterial toxins. He is a J. C. Bose National fellow of the Department of Science and Technology at CCMB and an elected fellow of the Indian Academy of Sciences, National Academy of Sciences, India and the Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded Nagaraj the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1994, for his contributions to biological sciences.

    Ghanshyam Swarup is an Indian molecular biologist, a J. C. Bose National Fellow and the head of the Ghanshyam Swarup Research Group of the Centre for Cellular and Molecular Biology. He is known for his studies on glaucoma and the discovery of protein tyrosine phosphatase, a new protein influencing the regulation of cell proliferation. Swarup is an elected fellow of the Indian Academy of Sciences, the Indian National Science Academy and the National Academy of Sciences, India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1996, for his contributions to biological sciences.

    Kanury Raoalso known as Kanury Venkata Subba Rao is an Indian immunologist. He was the head of the Drug Discovery Research Centre (DDRC) at the Translational Health Science and Technology Institute (THSTI) Faridabad. He is known for his studies in the fields of peptide synthesis and cell signaling and the design of synthetic peptide vaccines. He is an elected fellow of the Indian Academy of Sciences, National Academy of Sciences, India and the Indian National Science Academy. and a recipient of several awards including the Millennium Plaque of Honour of the Indian Science Congress and the National Bioscience Award for Career Development. The Council of Scientific and Industrial Research awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, in 1997, for his contributions to biological sciences.

    Umesh Varshney is an Indian molecular biologist, academician and the head of a laboratory at the Indian Institute of Science, Bengaluru. He is a J. C. Bose National Fellow of the Department of Science and Technology and is known for his studies on protein synthesis and DNA repair in Escherichia coli and Mycobacterium tuberculosis. An elected fellow of the Indian Academy of Sciences, Indian National Science Academy and the National Academy of Sciences (India), he is also a recipient of the National Bioscience Award for Career Development of the Government of India. The Council of Scientific and Industrial Research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2001, and then in 2014 with the G. N. Ramachandran Gold Medal for Excellence in Biological Sciences & Technology for his contributions to biological sciences.

    Raghavan Varadarajan is an Indian biophysicist and a professor at the Indian Institute of Science. He is known for his researches in the fields of protein structure and protein folding and his contributions in developing vaccines and drugs for treating a type of fatal influenza and HIV-1. He is a former J. C. Bose National Fellow of the Department of Science and Technology and an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2002, for his contributions to biological sciences.

    Vinod Bhakuni was an Indian molecular biophysicist and the head of the Molecular and Structural Biology Division of the Central Drug Research Institute (CDRI). He was the founder of the Protein Chemistry laboratory of CDRI and was known for his contributions to the study of protein folding. A recipient of the National Bioscience Award for Career Development, he was an elected fellow of the Indian Academy of Sciences, Indian National Science Academy and the National Academy of Sciences, India. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2006, for his contributions to biological sciences.

    Narayanaswamy Srinivasan was an Indian molecular biophysicist and a professor and the head of Proteins: Structure, Function and Evolutionary Group at the Molecular Biophysics Unit of the Indian Institute of Science. He is known for his researches in the fields of computational genomics and protein structure analysis. An elected fellow of the Indian Academy of Sciences and the National Academy of Sciences, India, he is a J. C. Bose National fellow of the Department of Biotechnology and a recipient of the National Bioscience Award for Career Development of the Department of Science and Technology. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2007, for his contributions to biological sciences.

    Sanjeev Anant Galande is an Indian cell biologist, epigeneticist, academic, former Chair of Biology and the Dean of Research and Development at the Indian Institute of Science Education and Research, Pune. He heads the Laboratory of Chromatin Biology and Epigenetics at the Indian Institute of Science Education and Research, Pune. He is the founder of the Centre of Excellence in Epigenetics at IISER Pune and is known for his studies on higher-order chromatin architecture and how it influences spatiotemporal changes in gene expression. He is an elected fellow of the Indian National Science Academy and the Indian Academy of Sciences and a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2010, for his contributions to biological sciences.

    Shantanu Chowdhury is an Indian structural biologist and a professor at Institute of Genomics and Integrative Biology of the Council of Scientific and Industrial Research. He is known for developing a mechanism for gene regulation mediated by DNA Secondary-Structure in diverse cellular contexts. An elected fellow of the National Academy of Sciences, India, he is a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology in 2010. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2012, for his contributions to biological sciences.

    Balasubramanian Gopal is an Indian structural biologist, molecular biophysicist and a professor at the Molecular Biophysics Unit of the Indian Institute of Science. He is known for his studies on cell wall synthesis in Staphylococcus aureus and is an elected fellow of the National Academy of Sciences, India, Indian National Science Academy and the Indian Academy of Sciences. He received the National Bioscience Award for Career Development of the Department of Biotechnology in 2010. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2015, for his contributions to biological sciences.

    Rishikesh Narayanan is an Indian neuroscientist, computer engineer and a professor at the Molecular Biophysics Unit (MBU) of the Indian Institute of Science. He is the principal investigator at the Cellular Neurophysiology Laboratory of MBU where his team is engaged in researches on experimental and theoretical aspects of information processing in single neurons and their networks. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 2016, for his contributions to biological sciences.

    Gattamraju Ravindra Kumar is an Indian laser physicist and a senior professor of Nuclear and Atomic Physics at Tata Institute of Fundamental Research. Known for his research on Ultrashort pulse and Warm dense matter, Kumar is an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, for his contributions to physical sciences in 2003. He is also a recipient of the B. M. Birla Science Prize and Infosys Prize.

    Madan Rao is an Indian condensed matter and biological physicist and a senior professor at National Centre for Biological Sciences. Known for his research on molecular dynamics on cell surface, Rao is an elected fellow of the Indian Academy of Sciences and the Indian National Science Academy. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, for his contributions to physical sciences in 2004.

    References

    1. 1 2 "The Code Breaker: Upinder S. Bhalla". India Today. 10 September 2011. Retrieved 25 October 2016.
    2. "Brief Profile of the Awardee". Shanti Swarup Bhatnagar Prize. 2016. Retrieved 5 October 2016.
    3. 1 2 "Fellow profile – Bhalla". Indian Academy of Sciences. 2016. Retrieved 6 October 2016.
    4. 1 2 "Indian fellow". Indian National Science Academy. 2016. Retrieved 25 October 2016.
    5. 1 2 "View Bhatnagar Awardees". Shanti Swarup Bhatnagar Prize. 2016. Retrieved 5 October 2016.
    6. "Infosys Prize". infosys-science-foundation.com. Retrieved 1 December 2017.
    7. "Infosys Prize – Laureates 2017 – Prof. Upinder S. Bhalla". infosys-science-foundation.com. Retrieved 1 December 2017.
    8. 1 2 "Upinder Singh Bhalla on Neurotree". Neurotree. 2016. Retrieved 25 October 2016.
    9. "Upinder Singh Bhalla on Vidwan". Vidwan. 2016. Retrieved 25 October 2016.
    10. "Lab members". National Centre For Biological Sciences. 2016. Retrieved 25 October 2016.
    11. "Handbook of Shanti Swarup Bhatnagar Prize Winners" (PDF). Council of Scientific and Industrial Research. 1999. p. 34. Retrieved 5 October 2016.
    12. "Computational and Experimental approaches to Memory and Plasticity". National Centre for Biological Sciences. 2016. Retrieved 25 October 2016.
    13. "Contact US". Moose.ncbs. 2016. Retrieved 25 October 2016.
    14. "Sachin Deshmukh". Wellcome Trust. 2016. Retrieved 25 October 2016.
    15. "INSA Year Book 2016". Indian National Science Academy. 2016. pp. 11 of 337. Retrieved 25 October 2016.
    16. "Infosys Prize – Laureates 2017 – Prof. Upinder S. Bhalla". infosys-science-foundation.com. Retrieved 1 December 2017.