Kuppamuthu Dharmalingam | |
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Born | Pollachi, Tamil Nadu, India | 3 January 1949
Nationality | Indian |
Alma mater |
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Known for | Induction of mutagenic DNA repair in Escherichia coli Proteomics of eye diseases |
Awards | 1992 Shanti Swarup Bhatnagar Prize |
Scientific career | |
Fields | |
Institutions |
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Doctoral advisor | J. Jayaraman |
Kuppamuthu Dharmalingam (born 3 January 1949) is an Indian proteomicist, geneticist, academic and the founder of Centre of Excellence in Bioinformatics at Madurai Kamaraj University. He is known for his contributions in the fields of eye disease proteomics and mutagenic DNA repair in Escherichia coli. [1] He is an elected fellow of the Indian Academy of Sciences [2] and the National Academy of Sciences, India. [3] The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1992, for his contributions to biological sciences. [4]
Born on 3 January 1949 in Pollachi, a border town in the South Indian state of Tamil Nadu, Kuppamuthu Dharmalingam did his schooling at Gandhi Kala Nilayam High School and secured his graduate and master's degrees in zoology from Thiagarajar College, Madurai before enrolling for PhD at Madurai Kamaraj University (MKU) under the guidance of J. Jayaraman, working on yeast mitochondrial membrane biogenesis .[ citation needed ] After obtaining his doctoral degree, he did his post-doctoral research with Edward D. Goldberg at Tufts University School of Medicine on genetics of bacteriophages. Returning to India, he joined MKU [5] and spent his entire academic career there but had a short stint at University of Geneva in between. During his early researches on Escherichia coli, a gram-negative bacterium, he discovered the induction of mutagenic DNA repair during restriction of nonglucosylated T4 DNA and the alleviation of restriction by SOS functions. [6] Subsequently, he studied the pathogenesis of Mycobacterium leprae using proteomics tools and discovered the single nucleotide polymorphism in the unique small alpha crystalline like heat shock protein in the gram-positive bacterium. [7] His researches have been documented in over 200 articles; ResearchGate, an online repository of scientific papers, has listed 48 of them. [8]
It was during his tenure at the MKU, the Centre of Excellence in Bioinformatics was established at the university in 1986.[ citation needed ] He is a life member of the Proteomics Society, India (PSI), [9] editor of its newsletter, [10] a former member of its executive council and was the convener of the workshop, Clinical Proteomics: Methods and Applications, conducted by PSI in October 2014. [11] He is a Distinguished Research Professor of the Department of Biotechnology and an elected fellow of the Indian Academy of Sciences [2] and the National Academy of Sciences, India. [3] The Council of Scientific and Industrial Research awarded him the Shanti Swarup Bhatnagar Prize, one of the highest Indian science awards, in 1992. [4]
Post retirement, Dharmalingam has been working since 2013 as a director of Aravind Medical Research Foundation, a Tamil Nadu-based research centre, ophthalmic hospital chain and a World Health Organization collaborating centre for the prevention of blindness. [12]
Madurai Kamaraj University (MKU) is a public state university located in the Madurai city, in southern Tamil Nadu, India, that was established in 1966. MKU is one of the 15 universities in India with the University with Potential for Excellence status, which was awarded by the University Grants Commission (UGC) in India. In 2021, the university was awarded an 'A++' grade from the National Assessment and Accreditation Council (NAAC) in its 4th cycle.
Mohan Rao Chintalagiri is an Indian molecular biologist renowned for his contributions to the fields of biophysics and molecular biology. He has earned international recognition for his work on molecular chaperones as well as his contribution to the field of photoacoustic spectroscopy in health and disease. He is a former Director of the Centre for Cellular and Molecular Biology (CCMB) and served as a CSIR-Distinguished Scientist. He received the Shanti Swarup Bhatnagar Prize in 1999, the highest science honor in India.
Sathees C. Raghavan is a Professor in the Department of Biochemistry at the Indian Institute of Science, Bangalore, India. He is from Kannur, Kerala. He was awarded the Shanti Swarup Bhatnagar Prize for science and technology, the highest science award in India, for the year 2013 in the biological science category. He was awarded the prize for his research work on novel DNA repair inhibitors that can target cancer cells. He received his BSc in Zoology from Payyannur College, Payyannur, MSc in Zoology with Entomology Specialization from University Center, Calicut University, Calicut, and PhD in Zoology from Banaras Hindu University, Varanasi India in 2000. He completed postdoctoral research at the University of Southern California Los Angeles from 1999 to 2006. His main research interests are cancer genetics, genomic instability, DNA repair, and recombination. Raghavan played the important role of convener of the lecture workshop on Recent Advances in Biotechnology of Health and Disease (BHD-2011) organized by Madurai Kamaraj University in 2011.
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Ramamirtha Jayaraman was an Indian geneticist, known for his studies on bacteria, especially on Escherichia coli. His researches on the control of transcription of bacteria are known to have evidenced the participation of accessory factors in transcription and their interactions with RNA polymerase. He was a professor at the Madurai Kamaraj University (MKU) and a former scientist at Tata Institute of Fundamental Research. Post his retirement, he served as an emeritus scientist at MKU. He authored the reference manual, Jayaraman Laboratory Manual in Molecular Genetics and several pamphlets and articles; PubMed, an online repository of medical papers has listed 59 of them. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1982, for his contributions to biological sciences.
Thavamani Jegajothivel Pandian, a retired professor of Madurai Kamaraj University (MKU), is an Indian geneticist and ecologist, known for his pioneering studies in bioenergetics and animal ecology. A recipient of the WorldFish Naga Award, he is a former chairman of the Task Force Committee on Aqua and Marine Biotechnology of the Department of Biotechnology of the Government of India, a former president and a fellow of The World Academy of Sciences and an elected fellow of the Indian National Science Academy, National Academy of Sciences, India, Indian Academy of Sciences and the National Academy of Agricultural Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1984, for his contributions to biological sciences.
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