John A. Pollock (professor)

Last updated
John A. Pollock
NationalityAmerican
CitizenshipUnited States
Alma materSyracuse University (B.S., M.S., Ph.D.)
AwardsAAAS Fellow

Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring

Contents

Apple Award for Distinguished Educator

Emmy Award for Children/Youth/Teen Program or Special

Emmy Award for Musical Composition/Arrangement

Parents' Choice Award

Carnegie Science Award
Scientific career
FieldsMolecular neurobiology, Science and health literacy education
InstitutionsDuquesne University
Doctoral advisor Edward Lipson, Seymour Benzer

John A. Pollock, is a Full Professor of Biological Science at Duquesne University Bayer School of Natural and Environmental Sciences, where he researches and teaches molecular neurobiology. He is Principal Investigator for The Partnership in Education, a non-profit multidisciplinary health literacy and informal science education project at Duquesne University funded primarily through a Science Education Partnership Award(SEPA) from the National Institute of General Medical Sciences, a component of the National Institutes of Health. [1]

Pollock holds the additional title of co-director for the Chronic Pain Research Consortium at Duquesne University. [2] [3] [4] He serves as a faculty affiliate at the BrainHub at Carnegie Mellon University and separately at the McGowan Institute for Regenerative Medicine, University of Pittsburgh/UPMC. [5]

Education

After receiving a B.S. and M.S. in physics from Syracuse University, Pollock earned his Ph.D. in biophysics in 1984 under the guidance of Dr. Edward Lipson. He did his post doctoral training at the California Institute of Technology with Seymour Benzer, where he studied the molecular neurogenetics of the developing eye and brain. [5]

Scientific career

Pollock worked at Carnegie Mellon University as an assistant and associate professor of biology and director of biological sciences graduate programs. In 2001 he became an associate professor of biology and then full professor at Duquesne University, where he continues his research in molecular neurobiology and serves as director of the graduate program. [1]

Pollock's research in neurobiology focused on the development of nerve cells in the fruit fly Drosophila. His early work explored the cell specific expression of genes such as sevenless, the opsins and arrestins. He also helped to develop techniques for the subcellular localization of mRNAs by high voltage electron microscopy. [1] His research has more recently identified that the RUNX1 transcription factor, Lozenge, initially influences cells with undetermined fates to choose survival over death, while Lozenge proteins contribute to how a cell chooses a specific fate. Following his independent cloning of TRP in the 1980s, [6] Pollock has re-focused his research on TRP related proteins that are involved in pain sensation in the peripheral nervous system. [1] [5] [7]

Pollock also collaborates with Jelena Janjic, Ph.D. of the School of Pharmacy of the Rangos School of Health Sciences at Duquesne University analyzing the involvement of neuroinflammation in the changes in TRPV1 expression [8] and the attenuation of inflammation with nano-emulsion delivered drug therapy. [9] In addition to neurobiology, Pollock has taught such subjects as developmental biology, light microscopy, physics, calculus, astronomy and ethics. [10]

Informal science education

The Partnership in Education

As director and executive producer of The Partnership in Education, Pollock specializes in creating planetarium shows and interactive multimedia that visualize topics in health and biology. Several past productions have focused on the potential for stem cell and tissue engineering research to help patients with bone, heart and spinal cord trauma and disease, as well as autoimmune diseases like Type I Diabetes. [11]

Pollock initially became interested in animation as a way to simplify and communicate important topics in science while a graduate student at Syracuse University, where he was the only science major in his animation class. [12] As a research fellow at the STUDIO for Creative Inquiry at Carnegie Mellon, an interdisciplinary arts center that enables art-science collaboration, [13] he began collaborating with colleague Patricia Maurides [14] and the Pittsburgh Tissue Engineering Initiative (PTEI) in 1996. He acted as science adviser to Journey into the Living Cell (1996) and co-director and science adviser for the internationally distributed Gray Matters: The Brain Movie (2000). [15] [16]

Building on these initial successes, in 2000 Pollock (as co-PI) and his collaborators at the STUDIO for Creative Inquiry and PTEI received a $1.62 million five-year Science Education Partnership Award (SEPA) from the National Center for Research Resources. [10] In 2001, at Duquesne University, Pollock founded The Partnership in Education focused on developing digital media for informal STEM education. [17] Pollock received a second SEPA in 2006 and then a third SEPA in 2014 from the National Institute of General Medical Sciences (NIGMS). [1]

Planetarium shows

Since 2000, Pollock has directed and produced several health literacy planetarium shows, including Tissue Engineering for Life, Regenerobot and the Robot Science Fair, Dr. Allevable's Unbelievable Laboratory – Bone and Heart,Our Cells, Our Selves, and How We Grow. [11] Many have been shown at the Carnegie Science Center Buhl Planetarium, and have been distributed to science centers and educators worldwide. [18]

Partnering with the Entertainment Technology Center (ETC), Pollock led the production of several video games that expand upon lessons in the films. He received national recognition at the 2010 Games for Health conference. [19]

Charles Darwin Synthetic Interview

Upon receiving the 2008 Darwin Evolution/Revolution Award from the NIH, Pollock and his team marked the bicentennial of the birth of Charles Darwin with a year-long celebration titled "Darwin 2009: A Pittsburgh Partnership". The life and intellectual impact of Darwin was celebrated in Pittsburgh, Pennsylvania, with a citywide series of events for children, teachers, students, and the general public. Unique aspects of Darwin's accomplishments were highlighted using the distinct abilities and resources of six major cultural institutions throughout Pittsburgh. [20]

The key event was the Charles Darwin Synthetic Interview, an interactive display created in partnership with the ETC that allows visitors to ask 199 questions to a virtual re-creation of Darwin. [21] The exhibit is installed as a permanent installation at the Carnegie Science Center in Pittsburgh, and the software has been used as part of the science curriculum of Pittsburgh Public Schools. [22] In 2015, Pollock released the Charles Darwin Synthetic Interview mobile app for iOS and Android devices, an adaptation of the original software. [23] The app received a Parents' Choice Award in 2016. [24]

Scientastic!

Other projects led by Pollock include Scientastic! , a combination live-action and animated television show of two episodes for pre-teens and teens that explores topics in health and science, as well as social issues. [25]

The second episode titled "Are You Sleeping?" explored the science of sleep and was distributed to public television stations throughout the United States by American Public Television. It aired in April 2014 and was made available for digital download. [26] In 2015, the episode won two Emmy Awards from the National Academy of Television Arts and Sciences (Mid-Atlantic Chapter); the Emmy Award for Children/Youth/Teen Program or Special and the Emmy Award for Musical Composition/Arrangement. [27]

The pilot episode titled "Sticks and Stones" debuted on WQED, Pittsburgh's local PBS station, in September 2010 [28] and focused on broken bones and bone regeneration. It starred Riverdale actress Lili Reinhart as the show's main character. [29]

Mobile apps

In addition to the Charles Darwin Synthetic Interview app, Pollock has led the development of several mobile apps through The Partnership in Education. Powers of Minus Ten – Bone, a companion app to Scientastic! "Sticks and Stones" about bone biology, received recognition by Apple in the 2011 App Store Rewind and has been downloaded over 600,000 times. [30] [31]

Pollock later developed a mobile app series titled BiblioTech, which uses an interactive narrative platform. BiblioTech "CityHacks: In Search of Sleep", a companion app to Scientastic! "In Search of Sleep," further explores stories on the need for sleep. [32] In 2016, the app received a Parents' Choice Award [33] and a bronze honor at the international 2016 Serious Play Conference. [34] Subsequently, an app on sports-related concussion titled BiblioTech "Rebound: Beating Concussions" won a Parents' Choice Award in 2018. The app uses "Adaptive Reader" software, which allows readers to switch the reading level of the text. [35] [36]

Awards

In 2018, Pollock was named a Fellow of the American Association for the Advancement of Science (AAAS), the world's largest scientific society. [37] [38] Pollock is a recipient of the 2018 Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring, the highest national mentoring award bestowed by the White House, which recognizes those who have "demonstrated excellence in mentoring individuals from groups that are underrepresented in STEM education and workforce." [39] [40] Pollock also received the 2011 Carnegie Science Award honoring his efforts in informal science education [41] and was named an Apple Distinguished Educator in 2017. [1] [42] He has been a featured speaker at a TEDxYouth conference in 2016 and engages in community service by volunteering as a reading tutor, among other activities. [1] [5]

Selected awards

Funding

Selected publications

  1. B. Kantorski, C. W. Sanford-Dolly, D. R. Commisso, J. A. Pollock (2019). Backward design as a mobile application development strategy. Educational Technology Research and Development, 67(3), 711–731. [44]
  2. M. Saleem, A. Stevens, B. Deal, L. Liu, J. M. Janjic, J. A. Pollock (2019). New Best Practice for Validating Tail Vein Injections in Rat with Near-infrared-Labeled Agents. J. Vis. Exp. (146), e59295, doi:10.3791/59295. [45]
  3. M. Janjic, K. Vasudeva, M. Saleem, A. Stevens, L. Liu, S. Patel, J. A. Pollock (2018). Low-dose NSAIDs reduce pain via targeted nanoemulsion delivery to neuroinflammation in rat. Journal of Neuroimmunology, 318, 72–79. [9]
  4. D. J. Lampe, B. Kantorski, J. A. Pollock (2018) Charles Darwin Synthetic Interview: A 19th century scientist speaks in the 21st century. Journal of STEM Outreach, 1(1). [46]
  5. B. Kolber, J. Janjic, J. A. Pollock, K Tidgewell (2016). Summer undergraduate research: A new pipeline for pain clinical practice and research. BMC Medical Education,16(1),135. [47]
  6. K. Vasudeva, Y. Vodovotz, N. Azhar, D. Barclay, J. M. Janjic, J. A. Pollock (2015). In vivo and systems biology studies implicate IL-18 as a central mediator in chronic pain. Journal of Neuroimmunology, 283, 3-49. [48]
  7. K. Vasudeva, K. Andersen, B. Zeyzus-Johns, S. K. Patel, T. K. Hitchens, J. M. Janjic, J. A. Pollock (2014). Imaging neuroinflammation in vivo in a neuropathic pain rat model with near-infrared fluorescence and 19F magnetic resonance. PLOS One, 9(2), e90589. [8]
  8. A. Wilson, L. Gonzalez, J. A. Pollock (2012). Evaluating learning and attitudes on tissue engineering: A study of children viewing animated digital dome shows detailing the biomedicine of tissue engineering. Tissue Engineering (Part A), 18(5-6), 576–586. [49]
  9. J. Ricou, J. A. Pollock (2012). The Tree, The Spiral And The Web of Life: A Visual Exploration. Leonardo Journal, 45(1), 18–25. [50]
  10. K. Lawrence, C. Stilley, J.A. Pollock, D. Webber, E. Quivers (2011). A family-centered educational program to promote independence in pediatric heart transplant recipients. Progress in Transplantation, 21(1), 61–66. [51]
  11. N.A. Siddall, G.R. Hime, J.A. Pollock, P. Batterham (2009). Ttk69-dependent repression of lozenge prevents the ectopic development of R7 cells in the Drosophila larval eye disc. Biomed Central: Developmental Biology, 9(64). [52]
  12. K. Jackson-Behan, J. Fair, S. Singh, M. Bogwitz, T. Perry, V. Grubor, F. Cunningham, C. Nichols, T. Cheung, P. Batterham and J.A. Pollock (2005). Alternative splicing removes an Ets interaction domain from Lozenge during Drosophila eye development. Development Genes and Evolution, 215(8), 423–435. [53]
  13. B. Gillo, I. Chorna, H. Cohen, B. Cook, I. Manistersky, 0. Devary, A. Arnon, A. Baumann, U. B. Kaupp, J. A. Pollock, Z. Selinger, B. Minke (1996). Co-expression of Drosophila TRP and TRPL in Xenopus oocytes reconstitutes a capacitative Ca2+ entry similar to the light-activated conductance. Proceedings of the National Academy of Sciences USA, 93(24), 14146–14151. [54]
  14. R. C. Hardie, A. Peretz, J. A. Pollock, B. Minke (1993). Ca2+ Limits the development of the lightresponse in Drosophila photoreceptors. Proceedings of the Royal Society B: Biological Sciences, 252(1335), 223–229. [6]
  15. J. A. Pollock and Seymour Benzer (1988). Transcript localization of four opsin genes In the three visual organs in Drosophila; RH2 is ocellus specific. Nature, 333(6175), 779–782. [55]
  16. U. Banerjee, P. J. Renfranz, J. A. Pollock, Seymour Benzer (1987). Molecular characterization and expression of sevenless, a gene involved in neural pattern formation in the Drosophila eye. Cell, 49(2), 281–291. [56]

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References

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  2. ↑ "Chronic Pain Research Consortium".
  3. ↑ "Consortium Faculty and Researchers". duq.edu. Retrieved 2019-05-29.
  4. ↑ Ferrick-Roman, Karen (Fall 2014). "Unraveling the Mysteries of Pain" (PDF). Duquesne University Magazine. Retrieved May 28, 2019.
  5. 1 2 3 4 "John A. Pollock, PhD | Regenerative Medicine at the McGowan Institute". mirm.pitt.edu. Retrieved 2018-11-15.
  6. 1 2 Hardie, R. C.; Peretz, A.; Pollock, J. A.; Minke, B. (1993-06-22). "Ca2+ limits the development of the light response in Drosophila photoreceptors". Proceedings. Biological Sciences. 252 (1335): 223–229. doi:10.1098/rspb.1993.0069. ISSN   0962-8452. PMID   8394583. S2CID   34422291.
  7. ↑ Vasudeva, Kiran; Andersen, Karl; Zeyzus-Johns, Bree; Hitchens, T. Kevin; Patel, Sravan Kumar; Balducci, Anthony; Janjic, Jelena M.; Pollock, John A. (2014). "Imaging neuroinflammation in vivo in a neuropathic pain rat model with near-infrared fluorescence and 19
    F     magnetic resonance"    . PLOS ONE. 9 (2): e90589. Bibcode:2014PLoSO...990589V. doi: 10.1371/journal.pone.0090589 . ISSN   1932-6203. PMC   3938771 . PMID   24587398.
  8. 1 2 Vasudeva, Kiran; Andersen, Karl; Zeyzus-Johns, Bree; Hitchens, T. Kevin; Patel, Sravan Kumar; Balducci, Anthony; Janjic, Jelena M.; Pollock, John A. (2014-02-28). "Imaging Neuroinflammation In Vivo in a Neuropathic Pain Rat Model with Near-Infrared Fluorescence and 19F Magnetic Resonance". PLOS ONE. 9 (2): e90589. Bibcode:2014PLoSO...990589V. doi: 10.1371/journal.pone.0090589 . ISSN   1932-6203. PMC   3938771 . PMID   24587398.
  9. 1 2 Janjic, Jelena M.; Vasudeva, Kiran; Saleem, Muzamil; Stevens, Andrea; Liu, Lu; Patel, Sravan; Pollock, John A. (2018-05-15). "Low-dose NSAIDs reduce pain via macrophage targeted nanoemulsion delivery to neuroinflammation of the sciatic nerve in rat". Journal of Neuroimmunology. 318: 72–79. doi:10.1016/j.jneuroim.2018.02.010. ISSN   1872-8421. PMC   6056892 . PMID   29519721.
  10. 1 2 Regenerative Medicine Partnership in Education : Press releases. "Project Overview - Tissue Engineering for Life."
  11. 1 2 "Home | The Partnership in Education". thepartnershipineducation.com. Retrieved 2018-11-15.
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  41. ↑ Daly, Jill (February 3, 2011). "Carnegie Science Awards Announced". Pittsburgh Post-Gazette. Retrieved 11 July 2011.
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  43. ↑ "2016 BEST OF THE CREATIVE INDUSTRIES". THE CREATIVE INDUSTRIES NETWORK. Retrieved 2018-11-16.
  44. ↑ Kantorski, Brinley; Sanford-Dolly, Camellia W.; Commisso, Danielle R.; Pollock, John A. (2019-06-01). "Backward design as a mobile application development strategy". Educational Technology Research and Development. 67 (3): 711–731. doi:10.1007/s11423-019-09662-7. ISSN   1556-6501. PMC   6502782 . PMID   31148910.
  45. ↑ Pollock, John A.; Janjic, Jelena; Liu, Lu; Deal, Brooke; Stevens, Andrea M.; Saleem, Muzamil (2019-04-19). "A New Best Practice for Validating Tail Vein Injections in Rat with Near-infrared-Labeled Agents". Journal of Visualized Experiments (146): e59295. doi: 10.3791/59295 . ISSN   1940-087X. PMID   31058897.
  46. ↑ Lampe, David; Kantorski, Brinley; Pollock, John (2018-01-15). "Charles Darwin Synthetic Interview: A 19th Century Scientists Speaks in the 21st Century". Journal of STEM Outreach. 1 (1): 3714. doi: 10.15695/jstem/v1i1.1 . ISSN   2576-6767. PMC   7351126 . PMID   32656506.
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  49. ↑ Wilson, Anna C.; Gonzalez, Laura L.; Pollock, John A. (March 2012). "Evaluating learning and attitudes on tissue engineering: a study of children viewing animated digital dome shows detailing the biomedicine of tissue engineering". Tissue Engineering. Part A. 18 (5–6): 576–586. doi:10.1089/ten.TEA.2011.0242. ISSN   1937-335X. PMC   3286820 . PMID   21943030.
  50. ↑ Ricou, Joana; Pollock, John Archie (February 2012). "The Tree, the Spiral and the Web of Life: A Visual Exploration of Biological Evolution for Public Murals". Leonardo. 45 (1): 18–25. doi: 10.1162/leon_a_00321 . ISSN   0024-094X. S2CID   57571811.
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  52. ↑ Siddall, Nicole A; Hime, Gary R; Pollock, John A; Batterham, Philip (2009-12-09). "Ttk69-dependent repression of lozenge prevents the ectopic development of R7 cells in the Drosophila larval eye disc". BMC Developmental Biology. 9: 64. doi: 10.1186/1471-213X-9-64 . ISSN   1471-213X. PMC   2797499 . PMID   20003234.
  53. ↑ Jackson Behan, Kristina; Fair, Jason; Singh, Shalini; Bogwitz, Michael; Perry, Trent; Grubor, Vladimir; Cunningham, Fiona; Nichols, Charles D.; Cheung, Tara L. (August 2005). "Alternative splicing removes an Ets interaction domain from Lozenge during Drosophila eye development". Development Genes and Evolution. 215 (8): 423–435. doi:10.1007/s00427-005-0490-0. ISSN   0949-944X. PMID   15868204. S2CID   33808285.
  54. ↑ Gillo, B.; Chorna, I.; Cohen, H.; Cook, B.; Manistersky, I.; Chorev, M.; Arnon, A.; Pollock, J. A.; Selinger, Z. (1996-11-26). "Coexpression of Drosophila TRP and TRP-like proteins in Xenopus oocytes reconstitutes capacitative Ca2+ entry". Proceedings of the National Academy of Sciences of the United States of America. 93 (24): 14146–14151. Bibcode:1996PNAS...9314146G. doi: 10.1073/pnas.93.24.14146 . ISSN   0027-8424. PMC   19508 . PMID   8943075.
  55. ↑ Pollock, J. A.; Benzer, S. (1988-06-23). "Transcript localization of four opsin genes in the three visual organs of Drosophila; RH2 is ocellus specific". Nature. 333 (6175): 779–782. Bibcode:1988Natur.333..779P. doi:10.1038/333779a0. ISSN   0028-0836. PMID   2968518. S2CID   4303934.
  56. ↑ Banerjee, U.; Renfranz, P. J.; Pollock, J. A.; Benzer, S. (1987-04-24). "Molecular characterization and expression of sevenless, a gene involved in neuronal pattern formation in the Drosophila eye". Cell. 49 (2): 281–291. doi:10.1016/0092-8674(87)90569-1. ISSN   0092-8674. PMID   2882857. S2CID   30098464.
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