Metaxalone, sold under the brand name Skelaxin, is a muscle relaxant medication used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. Its exact mechanism of action is not known, but it may be due to general central nervous system depression. It is a moderately strong muscle relaxant, with relatively low incidence of side effects.
Environmental Chemistry is a peer-reviewed scientific journal published by CSIRO Publishing. It covers all aspects of environmental chemistry, including atmospheric chemistry, (bio)geochemistry, climate change, marine chemistry, water chemistry, polar chemistry, fire chemistry, astrochemistry, earth and geochemistry, soil and sediment chemistry, and chemical toxicology. The editor-in-chief is Jamie Lead.
Haloxazolam, is a drug which is a benzodiazepine derivative. It has similar hypnotic properties as the benzodiazepine drugs triazolam, temazepam, and flunitrazepam and as such is indicated for the treatment of insomnia. A study in cats comparing estazolam and haloxazolam found that haloxazolam only affects gamma motor neurons, whereas estazolam affects both alpha and gamma motor neurons.
Critical Reviews in Toxicology is a peer-reviewed medical journal that publishes review articles on all aspects of toxicology. It is published by Taylor & Francis and the editor-in-chief is Roger O. McClellan. It was established in 1971 as CRC Critical Reviews in Toxicology, obtaining its current name in 1980.
α-Pyrrolidinopentiophenone is a synthetic stimulant of the cathinone class developed in the 1960s that has been sold as a designer drug. Colloquially, it is sometimes called flakka. α-PVP is chemically related to pyrovalerone and is the ketone analog of prolintane.
Phytomedicine is a monthly peer-reviewed medical journal covering the fields of phytotherapy, phytomedicine, and toxicology of plants and their extracts. The journal was established in 1994. It is published by Elsevier and the editor-in-chief is Alexander Panossian.
PCPr is an arylcyclohexylamine dissociative anesthetic drug with hallucinogenic and stimulant effects. It is around the same potency as phencyclidine, although slightly less potent than its ethyl homologue eticyclidine, and has reportedly been sold as a designer drug in Germany and other European countries since the late 1990s.
Toxicology and Applied Pharmacology is a scientific journal for original research pertaining to the action of chemicals, drugs, or natural products to animals or humans. The journal covers mechanistic approaches to physiological, biochemical, cellular, or molecular understanding of toxicologic/pathologic lesions and to methods used to describe these responses.
Toxicology and Industrial Health is a peer-reviewed medical journal that covers research in the fields of occupational health and toxicology. The editor-in-chief is Anthony L. Kiorpes. The journal was established in 1985 and is published by SAGE Publications.
Toxicologic Pathology is a peer-reviewed academic journal covering the field of toxicology. The editor-in-chief is Kevin A. Keane, a toxicologic pathologist employed at. It was established in 1972 and is published by SAGE Publications in association with the Society of Toxicologic Pathology, the British Society of Toxicological Pathology, and the European Society of Toxicologic Pathology.
Journal of Analytical Toxicology (JAT) is a peer-reviewed scientific journal focusing on analytical toxicology.
Food and Chemical Toxicology is a peer-reviewed scientific journal covering aspects of food safety, chemical safety, and other aspects of consumer product safety. It is published by Elsevier and was established in 1963. The editor-in-chief is José L. Domingo.
Jeremy K. Nicholson is a professor and pro vice chancellor of Health Sciences at Murdoch University in Perth, Western Australia, where he leads the Australian National Phenome Centre. He is also an emeritus professor of Biological Chemistry at Imperial College London and was the director and principal investigator of the MRC-NIHR National Phenome Centre until 2018.
Furanylfentanyl (Fu-F) is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug. It has an ED50 value of 0.02 mg/kg in mice. This makes it approximately one fifth as potent as fentanyl.
Marjorie Janice Groothuis Horning was an American biochemist and pharmacologist. She was considered to be a pioneer of chromatography for her work in developing new techniques and applying them to the study of drug metabolism. She demonstrated that drugs and their metabolites can be transferred from a pregnant woman to her developing child, and later through breast milk, from a mother to a baby. Horning's work made possible the prevention of birth defects, as doctors began to warn of the dangers of drugs, alcohol, and smoking during pregnancy.
The Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews is a biannual peer-reviewed scientific journal covering environmental health as it relates to carcinogenesis and toxicology. It was established in 1976 and is published by Taylor & Francis. The editor-in-chief is Peter P. Fu. According to the Journal Citation Reports, the journal has a 2015 impact factor of 3.667.
Naunyn-Schmiedeberg's Archives of Pharmacology is a peer-reviewed scientific journal of pharmacology. The journal was established in 1873 by Bernhard Naunyn, Oswald Schmiedeberg, and Edwin Klebs. It is the official journal of the German Society of Experimental and Clinical Pharmacology and Toxicology (DGPT), and of the Sphingolipid Club.
Environmental Toxicology and Chemistry is a monthly peer-reviewed scientific journal covering environmental toxicology and environmental chemistry. It was established in 1982 and is published by Wiley-Blackwell in conjunction with the Society of Environmental Toxicology and Chemistry. The founding editor-in-chief was C.H. Ward, and the current one is G.A. Burton, Jr.. According to the Journal Citation Reports, the journal has a 2021 impact factor of 4.218, ranking it 117th out of 279 journals in the category Environmental sciences and 29th out of 94 in the category Toxicology.
Clarivate Plc is a British-American publicly traded analytics company that operates a collection of subscription-based services, in the areas of bibliometrics and scientometrics; business / market intelligence, and competitive profiling for pharmacy and biotech, patents, and regulatory compliance; trademark protection, and domain and brand protection. In the academy and the scientific community, Clarivate is known for being the company which calculates the impact factor, using data from its Web of Science product family, that also includes services/applications such as Publons, EndNote, EndNote Click, and ScholarOne. Its other product families are Cortellis, DRG, CPA Global, Derwent, MarkMonitor, CompuMark, and Darts-ip, and also the various ProQuest products and services.
CUMYL-CBMICA (SGT-280) is an indole-3-carboxamide based synthetic cannabinoid receptor agonist which has been sold as a designer drug, first being identified in Germany in August 2019. Since the structure fell outside the German drug analogue law provisions at the time, an amendment was made to the law to expand the relevant definition, which came into effect in April 2020. It has been shown to act as a CB1 receptor agonist with an EC50 of 62.9nM.
