Julie Biteen

Last updated
Julie Biteen
Born
Julie Suzanne Biteen
Alma mater California Institute of Technology
Princeton University
Scientific career
Institutions Stanford University
Thesis Plasmon-Enhanced Silicon Nanocrystal Luminescence for Optoelectronic Applications  (2006)

Julie Suzanne Biteen is a Canadian-born American chemist who is professor of chemistry and biophysics at the University of Michigan. Her research considers the development of imaging systems for biological systems. She was named the Stanford University Sessler Distinguished Alumni Lecturer in 2021.

Contents

Early life and education

Biteen was born in Montreal. [1] Her father worked in Human Resources and her mother was a librarian. [1] As a child she enjoyed mathematics and thought that she might become a civil engineer. [1] During her undergraduate studies she became fascinated by fundamental scientific research. [1] Biteen majored in chemistry at Princeton University and worked under the supervision of Hershel Rabitz, where she studied maps for quantum control. After completing her bachelor's degree she moved to the California Institute of Technology (Caltech), where she worked toward a master's in applied physics. [2] She stayed at Caltech for her doctoral research, working alongside Harry Atwater and Nathan Lewis. Her doctoral research considered nanoparticle plasmonics and quantum dot optoelectronics. [3] She joined Stanford University as a postdoctoral scholar, where she worked on super-resolution imaging with William E. Moerner. As a postdoc she developed photoactivated localization microscopy systems to image Caulobacter crescentus , acquiring the first images of MreB, a protein found in bacteria. [1]

Research and career

Biteen was appointed to the faculty at the University of Michigan in 2010. She investigates microbial cell biology using advanced imaging techniques such as single-molecule and super-resolution imaging. [4] In particular, single-molecule microscopy [5] can provide nanoscale information about biological processes. She has used these techniques to understand how proteins recognise and bind histones during transcriptional silencing and to reveal information about the gut microbiome. [6] At the same time she has studied how plasmonic metal nanoantennas reshape the fluorescence of nearby molecules. [7]

Awards and honors

Selected publications

Related Research Articles

<span class="mw-page-title-main">Single-molecule experiment</span>

A single-molecule experiment is an experiment that investigates the properties of individual molecules. Single-molecule studies may be contrasted with measurements on an ensemble or bulk collection of molecules, where the individual behavior of molecules cannot be distinguished, and only average characteristics can be measured. Since many measurement techniques in biology, chemistry, and physics are not sensitive enough to observe single molecules, single-molecule fluorescence techniques caused a lot of excitement, since these supplied many new details on the measured processes that were not accessible in the past. Indeed, since the 1990s, many techniques for probing individual molecules have been developed.

<span class="mw-page-title-main">William E. Moerner</span> Nobel prize winning American chemical physicist

William Esco Moerner, also known as W. E. Moerner, is an American physical chemist and chemical physicist with current work in the biophysics and imaging of single molecules. He is credited with achieving the first optical detection and spectroscopy of a single molecule in condensed phases, along with his postdoc, Lothar Kador. Optical study of single molecules has subsequently become a widely used single-molecule experiment in chemistry, physics and biology. In 2014, he was awarded the Nobel Prize in Chemistry.

<span class="mw-page-title-main">Stefan Hell</span> Romanian-German physicist (born 1962)

Stefan Walter Hell is a Romanian-German physicist and one of the directors of the Max Planck Institute for Multidisciplinary Sciences in Göttingen, and of the Max Planck Institute for Medical Research in Heidelberg, both of which are in Germany. He received the Nobel Prize in Chemistry in 2014 "for the development of super-resolved fluorescence microscopy", together with Eric Betzig and William Moerner.

<span class="mw-page-title-main">Jennifer Lippincott-Schwartz</span> American biologist

Jennifer Lippincott-Schwartz is a Senior Group Leader at Howard Hughes Medical Institute's Janelia Research Campus and a founding member of the Neuronal Cell Biology Program at Janelia. Previously, she was the Chief of the Section on Organelle Biology in the Cell Biology and Metabolism Program, in the Division of Intramural Research in the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the National Institutes of Health from 1993 to 2016. Lippincott-Schwartz received her PhD from Johns Hopkins University, and performed post-doctoral training with Richard Klausner at the NICHD, NIH in Bethesda, Maryland.

Super-resolution microscopy is a series of techniques in optical microscopy that allow such images to have resolutions higher than those imposed by the diffraction limit, which is due to the diffraction of light. Super-resolution imaging techniques rely on the near-field or on the far-field. Among techniques that rely on the latter are those that improve the resolution only modestly beyond the diffraction-limit, such as confocal microscopy with closed pinhole or aided by computational methods such as deconvolution or detector-based pixel reassignment, the 4Pi microscope, and structured-illumination microscopy technologies such as SIM and SMI.

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The following outline is provided as an overview of and topical guide to biophysics:

<span class="mw-page-title-main">Martin Gruebele</span>

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Photo-activated localization microscopy and stochastic optical reconstruction microscopy (STORM) are widefield fluorescence microscopy imaging methods that allow obtaining images with a resolution beyond the diffraction limit. The methods were proposed in 2006 in the wake of a general emergence of optical super-resolution microscopy methods, and were featured as Methods of the Year for 2008 by the Nature Methods journal. The development of PALM as a targeted biophysical imaging method was largely prompted by the discovery of new species and the engineering of mutants of fluorescent proteins displaying a controllable photochromism, such as photo-activatible GFP. However, the concomitant development of STORM, sharing the same fundamental principle, originally made use of paired cyanine dyes. One molecule of the pair, when excited near its absorption maximum, serves to reactivate the other molecule to the fluorescent state.

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Suzanne A. Blum is an American professor of chemistry at the University of California, Irvine. Blum works on mechanistic chemistry, most recently focusing on borylation reactions and the development of single-molecule and single-particle fluorescence microscopy to study organic chemistry and catalysis. She received the American Chemical Society's Arthur C. Cope Scholar Award in 2023.

Rae Marie Robertson-Anderson is an American biophysicist who is a Professor and Associate Provost at the University of San Diego. She works on soft matter physics and is particularly interested in the transport and molecular mechanics of biopolymer networks. Robertson-Anderson is a member of the Council on Undergraduate Research.

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<span class="mw-page-title-main">Yoav Shechtman</span> Israeli physicist

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<span class="mw-page-title-main">Suliana Manley</span> American biophysicist

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Lynette Cegelski is an American physical chemist and chemical biologist who studies extracellular structures such as biofilms and membrane proteins. She is an associate professor of chemistry and, by courtesy, of chemical engineering at Stanford University. She is a Stanford Bio-X and Stanford ChEM-H affiliated faculty member.

Cryomicroscopy is a technique in which a microscope is equipped in such a fashion that the object intended to be inspected can be cooled to below room temperature. Technically, cryomicroscopy implies compatibility between a cryostat and a microscope. Most cryostats make use of a cryogenic fluid such as liquid helium or liquid nitrogen. There exists two common motivations for performing a cryomicroscopy. One is to improve upon the process of performing a standard microscopy. Cryogenic electron microscopy, for example, enables the studying of proteins with limited radiation damage. In this case, the protein structure may not change with temperature, but the cryogenic environment enables the improvement of the electron microscopy process. Another motivation for performing a cryomicroscopy is to apply the microscopy to a low-temperature phenomenon. A scanning tunnelling microscopy under a cryogenic environment, for example, allows for the studying of superconductivity, which does not exist at room temperature.

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Christy F. Landes is an American physical chemist who is the Jerry A. Walker Endowed Chair in chemistry at the University of Illinois Urbana-Champaign. She previously was the Kenneth S. Pitzer-Schlumberger Chair at Rice University. She seeks to understand the structure-function relationships in biological processes and materials. She was appointed a National Academy of Sciences Kavli Fellow in 2019.

Ulrike Endesfelder is a German physicist known for her work in Single-Molecule Microbiology and Super-resolution microscopy. She is the Group Leader of the Research Group Endesfelder and Full Professor (W3) at the Institute for microbiology and biotechnology at the University of Bonn in Bonn, Germany.

References

  1. 1 2 3 4 5 "Julie Biteen". The Biophysical Society. Retrieved 2022-03-21.
  2. "Professor Julie Biteen". daedalus.caltech.edu. Retrieved 2022-03-21.
  3. Biteen, Julie Suzanne (2007). Plasmon-enhanced silicon nanocrystal luminescence for optoelectronic applications (Thesis). Ann Arbor, Mich.: University Microfilms International. OCLC   232711628.
  4. "Julie Biteen | Princeton University Department of Chemistry". chemistry.princeton.edu. Retrieved 2022-03-21.
  5. Interview with Julie Biteen on Super-Resolution Symposium at BPS 2015 , retrieved 2022-03-21
  6. 1 2 "Sessler Lectureship: Professor Julie Biteen, University of Michigan | Department of Chemistry". chemistry.stanford.edu. Retrieved 2022-03-21.
  7. "Uncovering motion, mixtures and mislocalization in complex environments with super-resolution microscopy". sites.chem.utoronto.ca. Retrieved 2022-03-21.
  8. Biteen, Julie Suzanne. "2009 | Biteen Lab" . Retrieved 2022-03-21.
  9. "2009 Burroughs Wellcome Fund Annual Report by Burroughs Wellcome Fund - Issuu". issuu.com. Retrieved 2022-03-21.
  10. "NSF Award Search: Award # 1252322 - CAREER: Increasing the power of single-molecule bio-imaging with plasmon-enhanced fluorescence". www.nsf.gov. Retrieved 2022-03-21.
  11. "Julie Suzanne Biteen | Biteen Lab | Page 9" . Retrieved 2022-03-21.
  12. Biteen, Julie Suzanne. "– Julie wins the Journal of Physical Chemistry B Lectureship Award! | Biteen Lab" . Retrieved 2022-03-21.
  13. "Society Awards - The Biophysical Society". www.biophysics.org. Retrieved 2022-03-21.