KAT8 regulatory NSL complex subunit 2

KANSL2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4CY2
Identifiers
Aliases	KANSL2 , C12orf41, NSL2, KAT8 regulatory NSL complex subunit 2
External IDs	OMIM: 615488 MGI: 1916862 HomoloGene: 32367 GeneCards: KANSL2
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.11 Start 48,653,211 bp [1] End 48,682,238 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 F1 Start 98,517,658 bp [2] End 98,534,264 bp [2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • histone acetyltransferase activity (H4-K5 specific) • histone acetyltransferase activity (H4-K16 specific) • GO:0001948 protein binding • histone acetyltransferase activity (H4-K8 specific) Cellular component • histone acetyltransferase complex • nucleus • nucleoplasm • cytosol • plasma membrane • actin cytoskeleton • NSL complex Biological process • histone H4-K16 acetylation • histone H4-K8 acetylation • histone H4-K5 acetylation • chromatin organization Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54934	69612
Ensembl	ENSG00000139620	ENSMUSG00000022992
UniProt	Q9H9L4	Q8BQR4
RefSeq (mRNA)	NM_017822	NM_001289437 NM_001289438 NM_001289439 NM_001289440 NM_133714 NM_001359827
RefSeq (protein)	NP_060292	NP_001276366 NP_001276367 NP_001276368 NP_001276369 NP_598475 NP_001346756
Location (UCSC)	Chr 12: 48.65 – 48.68 Mb	Chr 15: 98.52 – 98.53 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

KAT8 regulatory NSL complex subunit 2 (KANSL2) also known as non-specific lethal 2 homolog (NSL2) is a protein that in humans is encoded by the KANSL2 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000139620 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022992 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
6. "Entrez Gene: C12orf41 chromosome 12 open reading frame 41".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Mata X, Taourit S, Le Provost F (2004). "Putative FLJ20436 gene characterisation in goat. Observed ubiquitous expression in goat and transgenic mice allowed to restrict the location of an hypothesised insulator element". Gene. 321: 137–44. doi:10.1016/j.gene.2003.08.004. PMID   14637001.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.