KBTBD10

KLHL41
Identifiers
Aliases	KLHL41 , KBTBD10, Krp1, NEM9, SARCOSIN, kelch like family member 41
External IDs	OMIM: 607701; MGI: 2683854; HomoloGene: 4421; GeneCards: KLHL41; OMA:KLHL41 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q31.1 Start 169,509,702 bp [1] End 169,526,258 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 C2 Start 69,500,464 bp [2] End 69,514,574 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibialis anterior muscle gastrocnemius muscle muscle of thigh biceps brachii Skeletal muscle tissue of biceps brachii Skeletal muscle tissue of rectus abdominis quadriceps femoris muscle body of tongue vastus lateralis muscle deltoid muscle Top expressed in knee joint ankle soleus muscle muscle of thigh medial head of gastrocnemius muscle tibialis anterior muscle skeletal muscle tissue extraocular muscle temporal muscle sternocleidomastoid muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function ubiquitin-protein transferase activity protein binding Cellular component cytoplasm M band cell projection pseudopodium endoplasmic reticulum membrane membrane ruffle Cul3-RING ubiquitin ligase complex plasma membrane sarcoplasmic reticulum endoplasmic reticulum sarcoplasmic reticulum membrane cytoskeleton nucleus cytosol Biological process regulation of skeletal muscle cell differentiation myofibril assembly regulation of myoblast differentiation protein ubiquitination skeletal muscle cell differentiation striated muscle contraction regulation of myoblast proliferation sarcomere organization skeletal muscle fiber development post-translational protein modification Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10324 228003 Ensembl ENSG00000239474 ENSMUSG00000075307 UniProt O60662 A2AUC9 RefSeq (mRNA) NM_006063 NM_001081087 RefSeq (protein) NP_006054 NP_001074556 Location (UCSC) Chr 2: 169.51 – 169.53 Mb Chr 2: 69.5 – 69.51 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Kelch repeat and BTB domain-containing protein 10 is a protein that in humans is encoded by the KBTBD10 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000239474 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075307 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Taylor A, Obholz K, Linden G, Sadiev S, Klaus S, Carlson KD (Apr 1999). "DNA sequence and muscle-specific expression of human sarcosin transcripts". Mol Cell Biochem. 183 (1–2): 105–12. doi:10.1023/A:1006824331819. PMID   9655184. S2CID   22774237.
6. "Entrez Gene: KBTBD10 kelch repeat and BTB (POZ) domain containing 10".

Further reading

• Foster LJ, Rudich A, Talior I, et al. (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC)". J. Proteome Res. 5 (1): 64–75. doi:10.1021/pr0502626. PMID   16396496.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Lim DS, Roberts R, Marian AJ (2001). "Expression Profiling of Cardiac Genes in Human Hypertrophic Cardiomyopathy: Insight Into the Pathogenesis of Phenotypes". J. Am. Coll. Cardiol. 38 (4): 1175–80. doi:10.1016/S0735-1097(01)01509-1. PMC   2776821 . PMID   11583900.
• Spence HJ, Johnston I, Ewart K, et al. (2000). "Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells". Oncogene. 19 (10): 1266–76. doi: 10.1038/sj.onc.1203433 . PMID   10713668.
• Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi: 10.1101/gr.6.9.807 . PMID   8889549.

External links

• KBTBD10 human gene location in the UCSC Genome Browser .
• KBTBD10 human gene details in the UCSC Genome Browser .