KCTD12

KCTD12
Identifiers
Aliases	KCTD12 , C13orf2, PFET1, PFETIN, potassium channel tetramerization domain containing 12
External IDs	OMIM: 610521 MGI: 2145823 HomoloGene: 16316 GeneCards: KCTD12
Gene location (Human)
Chr.	Chromosome 13 (human)
End	76,886,405 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	103,220,073 bp
RNA expression pattern
	Top expressed in
	trigeminal ganglion; ; urethra; ; bronchial epithelial cell; ; lactiferous duct; ; synovial joint; ; superficial temporal artery; ; lower lobe of lung; ; pericardium; ; parietal pleura; ; cardia;
	Top expressed in
	molar; ; pineal gland; ; dermis; ; body of femur; ; cerebellar vermis; ; calvaria; ; conjunctival fornix; ; uterus; ; olfactory bulb; ; external carotid artery;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA binding ; identical protein binding ;
Cellular component	cell junction ; postsynaptic membrane ; plasma membrane ; synapse ; extracellular exosome ; presynaptic membrane ; membrane ;
Biological process	protein homooligomerization ;
	Sources:Amigo / QuickGO
Orthologs
	115207
	239217
	ENSG00000178695
	ENSMUSG00000098557
	Q96CX2
	Q6WVG3
	NM_138444
	NM_177715
	NP_612453
	NP_808383
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 05, 2022

BTB/POZ domain-containing protein KCTD12 is a protein that in humans is encoded by the KCTD12 gene.^[5]^[6]

It may be associated with rumination ^[7] and Bipolar Disorder.^[8]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000178695 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000098557 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Resendes BL, Kuo SF, Robertson NG, Giersch AB, Honrubia D, Ohara O, Adams JC, Morton CC (Sep 2004). "Isolation from cochlea of a novel human intronless gene with predominant fetal expression". J Assoc Res Otolaryngol. 5 (2): 185–202. doi:10.1007/s10162-003-4042-x. PMC 2538407 . PMID 15357420.
↑ "Entrez Gene: KCTD12 potassium channel tetramerisation domain containing 12".
↑ Eszlari, Nora; Millinghoffer, Andras; Petschner, Peter; Gonda, Xenia; Baksa, Daniel; Pulay, Attila J.; Réthelyi, János M.; Breen, Gerome; Deakin, John Francis William; Antal, Peter; Bagdy, Gyorgy; Juhasz, Gabriella (2019). "Genome-wide association analysis reveals KCTD12 and miR-383-binding genes in the background of rumination". Translational Psychiatry. 9 (1): 119. doi:10.1038/s41398-019-0454-1. PMC 6423133 . PMID 30886212.
↑ "KCTD12 Gene - GeneCards | KCD12 Protein | KCD12 Antibody".

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID 8889548.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. S2CID 11683986.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi: 10.1074/mcp.M400085-MCP200 . PMID 15345747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948 . PMID 17353931.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000178695 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000098557 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15357420-5] Resendes BL, Kuo SF, Robertson NG, Giersch AB, Honrubia D, Ohara O, Adams JC, Morton CC (Sep 2004). "Isolation from cochlea of a novel human intronless gene with predominant fetal expression". J Assoc Res Otolaryngol. 5 (2): 185–202. doi:10.1007/s10162-003-4042-x. PMC 2538407 . PMID 15357420.

[entrez-6] "Entrez Gene: KCTD12 potassium channel tetramerisation domain containing 12".

[7] Eszlari, Nora; Millinghoffer, Andras; Petschner, Peter; Gonda, Xenia; Baksa, Daniel; Pulay, Attila J.; Réthelyi, János M.; Breen, Gerome; Deakin, John Francis William; Antal, Peter; Bagdy, Gyorgy; Juhasz, Gabriella (2019). "Genome-wide association analysis reveals KCTD12 and miR-383-binding genes in the background of rumination". Translational Psychiatry. 9 (1): 119. doi:10.1038/s41398-019-0454-1. PMC 6423133 . PMID 30886212.

[8] "KCTD12 Gene - GeneCards | KCD12 Protein | KCD12 Antibody".

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KCTD12

Related Research Articles

References

Further reading