KIF14

Last updated
KIF14
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KIF14 , MKS12, kinesin family member 14, MCPH20
External IDs OMIM: 611279 MGI: 1098226 HomoloGene: 8916 GeneCards: KIF14
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001305792
NM_014875

NM_001081258
NM_001287179

RefSeq (protein)

NP_001292721
NP_055690

NP_001274108

Location (UCSC) Chr 1: 200.55 – 200.62 Mb Chr 1: 136.39 – 136.46 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Kinesin-like protein KIF14 is a protein that in humans is encoded by the KIF14 gene. [5] [6]


Related Research Articles

<span class="mw-page-title-main">KIF23</span> Protein-coding gene in the species Homo sapiens

Kinesin-like protein KIF23 is a protein that in humans is encoded by the KIF23 gene.

<span class="mw-page-title-main">KIF1B</span> Mammalian protein found in Homo sapiens

Kinesin-like protein KIF1B is a protein that in humans is encoded by the KIF1B gene.

<span class="mw-page-title-main">KIF4A</span> Protein-coding gene in the species Homo sapiens

Chromosome-associated kinesin KIF4A is a protein that in humans is encoded by the KIF4A gene.

<span class="mw-page-title-main">KIF22</span>

Kinesin-like protein KIF22 is a protein that in humans is encoded by the KIF22 gene.

<span class="mw-page-title-main">KIF2C</span> Protein-coding gene in the species Homo sapiens

Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.

<span class="mw-page-title-main">KIF20A</span>

Kinesin-like protein KIF20A is a protein that in humans is encoded by the KIF20A gene.

<span class="mw-page-title-main">KIF21A</span>

Kinesin-like protein KIF21A is a protein that in humans is encoded by the KIF21A gene.

<span class="mw-page-title-main">Kinesin-associated protein 3</span> Protein-coding gene in the species Homo sapiens

Kinesin-associated protein 3 (KAP3) is a protein that in humans is encoded by the KIFAP3 gene. It is a non-motor, accessory subunit which co-oligomerizes with the motor subunits KIF3A and KIF3B or KIF3C, to form heterotrimeric kinesin-2 motor proteins. Kinesin-2 KAP subunits were initially characterized in echinoderms and mice.

<span class="mw-page-title-main">Kinesin-like protein KIF3B</span> Protein-coding gene in the species Homo sapiens

Kinesin-like protein KIF3B is a protein that in humans is encoded by the KIF3B gene. KIF3B is an N-type protein that complexes with two other kinesin proteins to form two-headed anterograde motors. First, KIF3B forms a heterodimer with KIF3A ; (KIF3A/3B), that is membrane-bound and has ATPase activity. Then KIFAP3 binds to the tail domain to form a heterotrimeric motor. This motor has a plus end-directed microtubule sliding activity that exhibits a velocity of ∼0.3 μm/s a. There are 14 kinesin protein families in the kinesin superfamily and KIF3B is part of the Kinesin-2 family, of kinesins that can all form heterotrimeric complexes. Expression of the three motor subunits is ubiquitous. The KIG3A/3B/KAP3 motors can transport 90 to 160 nm in diameter organelles.

<span class="mw-page-title-main">PRC1</span>

Protein Regulator of cytokinesis 1 (PRC1) is a protein that in humans is encoded by the PRC1 gene and is involved in cytokinesis.

<span class="mw-page-title-main">KIF18A</span>

Kinesin-like protein KIF18A is a protein that in humans is encoded by the KIF18A gene.

<span class="mw-page-title-main">KIFC1</span>

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.

<span class="mw-page-title-main">KIF13A</span> Protein-coding gene in the species Homo sapiens

Kinesin-like protein KIF13A is a protein that in humans is encoded by the KIF13A gene.

<span class="mw-page-title-main">MPHOSPH1</span>

Kinesin-like protein KIF20B is a protein that in humans is encoded by the KIF20B gene.

<span class="mw-page-title-main">KIF17</span> Protein-coding gene in the species Homo sapiens

Kinesin-like protein KIF17 is a protein that in humans is encoded by the KIF17 gene. KIF17 and its close relative, C. elegans OSM-3, are members of the kinesin-2 family of plus-end directed microtubule-based motor proteins. In contrast to heterotrimeric kinesin-2 motors, however, KIF17 and OSM-3 form distinct homodimeric complexes. Homodimeric kinesin-2 has been implicated in the transport of NMDA receptors along dendrites for delivery to the dendritic membrane, whereas both heterotrimeric and homodimeric kinesin-2 motors function cooperatively in anterograde intraflagellar transport (IFT) and cilium biogenesis.

<span class="mw-page-title-main">KIAA1279</span>

KIF1-binding protein, also known as Kinesin binding protein(KBP), is a protein that in humans is encoded by the KIAA1279 gene. The interaction of KBP with Kif15 is necessary for the localization of Kif15 to the microtubule plus-end at the spindle equator. Interaction between Kif15 and KBP is essential for the perfect alignment of chromosomes at the metaphase plate, and any defect in their interaction leads to delay in chromosomal alignment during mitosis. Anything that perturb the interaction of KBP and Kif15 can block the cells at mitosis, and hence it can be therapeutically used to control Kif15 upregulated cancer cells.

<span class="mw-page-title-main">KIF2A</span>

Kinesin-like protein KIF2A is a protein that in humans is encoded by the KIF2A gene.

<span class="mw-page-title-main">Kinesin-like protein KIF3C</span>

Kinesin-like protein KIF3C is a protein that in humans is encoded by the KIF3C gene.

<span class="mw-page-title-main">KIF16B</span> Protein-coding gene in the species Homo sapiens

Kinesin family member 16B, also known as KIF16B, is a protein which in humans is encoded by the KIF16B gene.

<span class="mw-page-title-main">KIF15</span>

Kinesin family member 15 is a protein that in humans is encoded by the KIF15 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000118193 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041498 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (Dec 1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 1 (5): 223–9. doi: 10.1093/dnares/1.5.223 . PMID   7584044.
  6. "Entrez Gene: KIF14 kinesin family member 14".

Further reading