KIF27

KIF27
Identifiers
Aliases	KIF27 , kinesin family member 27
External IDs	OMIM: 611253 MGI: 1922300 HomoloGene: 69235 GeneCards: KIF27
Gene location (Human)
Chr.	Chromosome 9 (human)
End	83,921,465 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	58,506,936 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; testicle; ; Achilles tendon; ; corpus callosum; ; endometrium; ; ganglionic eminence; ; sural nerve; ; thyroid gland; ; left lobe of thyroid gland; ; right lobe of thyroid gland;
	Top expressed in
	spermatid; ; spermatocyte; ; seminiferous tubule; ; olfactory epithelium; ; lateral ventricle; ; vestibular labyrinth; ; jejunum; ; secondary oocyte; ; superior frontal gyrus; ; esophagus;
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule binding ; nucleotide binding ; ATP binding ; microtubule motor activity ; plus-end-directed microtubule motor activity ; ATPase activity ;
Cellular component	cytoplasm ; cell projection ; cilium ; microtubule ; cytoskeleton ; kinesin complex ; extracellular region ;
Biological process	microtubule-based movement ; cell projection organization ; epithelial cilium movement involved in extracellular fluid movement ; ventricular system development ; cilium assembly ;
	Sources:Amigo / QuickGO
Orthologs
	55582
	75050
	ENSG00000165115
	ENSMUSG00000060176
	Q86VH2
	Q7M6Z4
NM_001271927 ; NM_001271928 ; NM_017576 ; NM_001354069 ; NM_001354070 ;
	NM_001354071
	NM_175214 ; NM_001360894
NP_001258856 ; NP_001258857 ; NP_060046 ; NP_001340998 ; NP_001340999 ;
	NP_001341000
	NP_780423 ; NP_001347823
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 05, 2022

Kinesin family member 27 (KIF27), also known as kinesin-4, is a human protein encoded by the KIF25 gene. It is part of the kinesin family of motor proteins.

Related Research Articles

Chromosome-associated kinesin KIF4A is a protein that in humans is encoded by the KIF4A gene.

Kinesin-like protein KIF18A is a protein that in humans is encoded by the KIF18A gene.

Kinesin-like protein KIF14 is a protein that in humans is encoded by the KIF14 gene.

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.

Kinesin-like protein KIF13A is a protein that in humans is encoded by the KIF13A gene.

Kinesin-like protein KIF20B is a protein that in humans is encoded by the KIF20B gene.

Kinesin heavy chain isoform 5C is a protein that in humans is encoded by the KIF5C gene.

Kinesin-like protein KIF17 is a protein that in humans is encoded by the KIF17 gene. KIF17 and its close relative, C. elegans OSM-3, are members of the kinesin-2 family of plus-end directed microtubule-based motor proteins. In contrast to heterotrimeric kinesin-2 motors, however, KIF17 and OSM-3 form distinct homodimeric complexes. Homodimeric kinesin-2 has been implicated in the transport of NMDA receptors along dendrites for delivery to the dendritic membrane, whereas both heterotrimeric and homodimeric kinesin-2 motors function cooperatively in anterograde intraflagellar transport (IFT) and cilium biogenesis.

KIF1-binding protein, also known as Kinesin binding protein(KBP), is a protein that in humans is encoded by the KIAA1279 gene. The interaction of KBP with Kif15 is necessary for the localization of Kif15 to the microtubule plus-end at the spindle equator. Interaction between Kif15 and KBP is essential for the perfect alignment of chromosomes at the metaphase plate, and any defect in their interaction leads to delay in chromosomal alignment during mitosis. Anything that perturb the interaction of KBP and Kif15 can block the cells at mitosis, and hence it can be therapeutically used to control Kif15 upregulated cancer cells.

Kinesin-like protein KIF2A is a protein that in humans is encoded by the KIF2A gene.

Kinesin-like protein KIF3C is a protein that in humans is encoded by the KIF3C gene.

Kinesin family member 16B, also known as KIF16B, is a protein which in humans is encoded by the KIF16B gene.

Kinesin family member 6 is a protein that in humans is encoded by the KIF6 gene. This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport.

Kinesin family member 13B is a protein that in humans is encoded by the KIF13B gene.

KIF4B is a human protein encoded by the gene KIF4B. It is part of the kinesin family of proteins, which are motor proteins involved in many cellular processes.

Kinesin family member 7 (KIF7), also known as kinesin-4, is a human protein encoded by the gene KIF7. It is part of the kinesin family of motor proteins.

Kinesin family member 9 (KIF9), also known as kinesin-9, is a human protein encoded by the KIF9 gene. It is part of the kinesin family of motor proteins.

Kinesin family member 12 (KIF12), also known as kinesin-12, is a human protein encoded by the gene KIF12. It is part of the kinesin family of motor proteins.

Kinesin family member 19 (KIF19) is a protein in humans encoded by the KIF19 gene. It is part of the kinesin family of motor proteins.

Kinesin family member 25 (KIF25), also known as kinesin-14, is a human protein encoded by the KIF25 gene. It is part of the kinesin family of motor proteins.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000165115 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060176 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000165115 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060176 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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