Karate at the Islamic Solidarity Games has been contested at every edition of the event. In 2005, men's events were contested and starting in 2013, both men's and women's events were contested. The sport was also contested at the 2022 Islamic Solidarity Games in Konya, Turkey. [1]
| Games | Year | Host city | Host country | Events |
|---|---|---|---|---|
| I | 2005 () | Mecca |  Saudi Arabia | 11 |
| II | 2010 | Tehran |  Iran | Cancelled |
| III | 2013 () | Palembang |  Indonesia | 17 [2] |
| IV | 2017 () | Baku |  Azerbaijan | 12 |
| V | 2022 () | Konya |  Turkey | 14 |
| VI | 2025 () | Riyadh | Saudi Arabia | 12 |
Updated after the 2025 Islamic Solidarity Games
| Rank | Nation | Gold | Silver | Bronze | Total |
|---|---|---|---|---|---|
| 1 | Iran | 13 | 16 | 11 | 40 |
| 2 | Azerbaijan | 11 | 8 | 9 | 28 |
| 3 | Turkey | 10 | 13 | 18 | 41 |
| 4 |  Egypt | 8 | 4 | 13 | 25 |
| 5 |  Morocco | 4 | 6 | 9 | 19 |
| 6 |  Uzbekistan | 4 | 1 | 4 | 9 |
| 7 | Saudi Arabia | 4 | 0 | 14 | 18 |
| 8 |  Kazakhstan | 3 | 1 | 3 | 7 |
| 9 |  Kuwait | 2 | 5 | 4 | 11 |
| 10 |  Jordan | 2 | 2 | 5 | 9 |
| 11 |  Malaysia | 2 | 2 | 2 | 6 |
| 12 |  Algeria | 1 | 6 | 16 | 23 |
| 13 |  Tunisia | 1 | 1 | 2 | 4 |
| 14 | Indonesia | 1 | 0 | 12 | 13 |
| 15 |  Pakistan | 0 | 1 | 0 | 1 |
| 16 |  United Arab Emirates | 0 | 0 | 3 | 3 |
| 17 |  Cameroon | 0 | 0 | 1 | 1 |
 Ivory Coast | 0 | 0 | 1 | 1 | |
 Libya | 0 | 0 | 1 | 1 | |
 Senegal | 0 | 0 | 1 | 1 | |
 Syria | 0 | 0 | 1 | 1 | |
| Totals (21 entries) | 66 | 66 | 130 | 262 | |