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Transfusion medicine is the branch of medicine that encompasses all aspects of the transfusion of blood and blood components including aspects related to hemovigilance. It includes issues of blood donation, immunohematology and other laboratory testing for transfusion-transmitted diseases, management and monitoring of clinical transfusion practices, patient blood management, therapeutic apheresis, stem cell collections, cellular therapy, and coagulation. Laboratory management and understanding of state and federal regulations related to blood products are also a large part of the field.
A blood bank is a center where blood gathered as a result of blood donation is stored and preserved for later use in blood transfusion. The term "blood bank" typically refers to a department of a hospital usually within a Clinical Pathology laboratory where the storage of blood product occurs and where pre-transfusion and Blood compatibility testing is performed. However, it sometimes refers to a collection center, and some hospitals also perform collection. Blood banking includes tasks related to blood collection, processing, testing, separation, and storage.
Lasker–DeBakey Clinical Medical Research Award is one of four annual awards presented by the Lasker Foundation. The Lasker–DeBakey award is given to honor outstanding work for the understanding, diagnosis, prevention, treatment, and cure of disease. This award was renamed in 2008 in honor of Michael E. DeBakey. It was previously known as the Albert Lasker Award for Clinical Medical Research.
The Canada Gairdner International Award is given annually by the Gairdner Foundation at a special dinner to five individuals for outstanding discoveries or contributions to medical science. Receipt of the Gairdner is traditionally considered a precursor to winning the Nobel Prize in Medicine; as of 2020, 98 Nobel Prizes have been awarded to prior Gairdner recipients.
Paroxysmal cold hemoglobinuria (PCH) or Donath–Landsteiner hemolytic anemia (DLHA) is an autoimmune hemolytic anemia featured by complement-mediated intravascular hemolysis after cold exposure. It can present as an acute non-recurrent postinfectious event in children, or chronic relapsing episodes in adults with hematological malignancies or tertiary syphilis. Described by Julius Donath (1870–1950) and Karl Landsteiner (1868–1943) in 1904, PCH is one of the first clinical entities recognized as an autoimmune disorder.
Philip Levine was an immuno-hematologist whose clinical research advanced knowledge on the Rhesus factor, Hemolytic disease of the newborn (HDN) and blood transfusion.
The Ernest Orlando Lawrence Award was established in 1959 in honor of a scientist who helped elevate American physics to the status of world leader in the field.
Karl Landsteiner was an Austrian American biologist, physician, and immunologist. He emigrated with his family to New York in 1923 at the age of fifty five for professional opportunities, working for the Rockefeller Institute.
The Sedgwick Memorial Medal, given by the American Public Health Association, was established in 1929 for distinguished service and advancement of public health knowledge and practice. It is considered the APHA's highest honor.
Sir Michael Houghton is a British scientist and Nobel Prize laureate. Along with Qui-Lim Choo, George Kuo and Daniel W. Bradley, he co-discovered Hepatitis C in 1989. He also co-discovered the Hepatitis D genome in 1986. The discovery of the Hepatitis C virus (HCV) led to the rapid development of diagnostic reagents to detect HCV in blood supplies, which has reduced the risk of acquiring HCV through blood transfusion from one in three to about one in two million. It is estimated that antibody testing has prevented at least 40,000 new infections per year in the US alone and many more worldwide.
Qui-Lim Choo is a Singapore-born scientist, who along with Michael Houghton, George Kuo and Daniel W. Bradley, co-discovered and cloned Hepatitis C in 1989. He also co-discovered the Hepatitis D genome in 1986. The discovery of Hepatitis C led to the rapid development of diagnostic reagents to detect Hepatitis C virus in blood supplies which has reduced the risk of acquiring hepatitis C through blood transfusion from one in three to about one in two million. It is estimated that antibody testing has prevented at least 40,000 new infections per year in the US alone and many more worldwide.
George William Gregory Bird was a British medical doctor, academic, researcher and haematologist known for his expertise in the fields of blood transfusion and immunohaematology. He founded the Department of Transfusion Medicine at the Armed Forces Medical College, Pune and was inducted into their Hall of Fame in 2010. A winner of the Karl Landsteiner Memorial Prize and Morten Grove Rasmussen Memorial Award of the American Association of Blood Banks, Gregory Bird was honoured by the Government of India in 1963, with the award of Padma Shri, the fourth highest Indian civilian award for his services to the nation.
Daniel W. Bradley is an important American virologist who, along with Michael Houghton, Qui-Lim Choo and George Kuo at Chiron Corporation, worked to help isolate the Hepatitis C virus in 1989. He graduated from San José State University in 1964 before going on to receive a master's degree in biochemistry from the University of California and a doctorate from the University of Arizona. He worked for the Centers for Disease Control and Prevention starting in 1971. He received the Karl Landsteiner Memorial Award of the American Association of Blood Banks in 1992, the Robert Koch Prize in 1993, and the Gairdner Foundation International Award in 2013.
George Ching-Hung Kuo is a Taiwanese-born scientist, who along with Michael Houghton, Qui-Lim Choo and Daniel W. Bradley, co-discovered and cloned the hepatitis C virus in 1989.
Lacy Rasco Overby was a virologist known for his contributions to Hepatitis B and Hepatitis C research.
Frederick Stratton was an English haematologist and an internationally recognized expert in blood transfusion. He is known for discovering one of the Rh allelomorphs.
Tibor Jack Greenwalt was an American hematologist who specialized in transfusion medicine. Greenwalt earned his medical degree from New York University Medical School in 1937 and completed a hematology fellowship under William Dameshek. After serving as a US Army physician in World War I, he settled in Milwaukee, Wisconsin, where he became a professor of medicine at the Marquette University School of Medicine. He was a founding member of the American Association of Blood Banks and served as president of the International Society of Blood Transfusion from 1966 to 1972.
The 2020 Nobel Prize in Physiology or Medicine was awarded to the American virologists Harvey J. Alter, Michael Houghton and Charles M. Rice "for the discovery of Hepatitis C virus." During the award ceremony on December 10, 2020, Prof. Gunilla Karlsson-Hedestam said:
"The discovery of the Hepatitis C virus by this year’s Laureates laid the foundation for our current understanding about how the virus survives in its niche during the long chronic phase of the infection, and how liver disease develops. And importantly, it led to the development of highly effective anti-viral medicines that now cure the infection in almost all treated persons."
References
- ↑ "AABB Memorial Award Descriptions". American Association of Blood Banks . Retrieved 5 October 2016.
- ↑ "AABB23: Presenting the First-Ever Landsteiner-Alter Award". News, American Association of Blood Banks (AAAB). 16 October 2023.