U.S. Route 42 is an east–west United States highway that runs southwest–northeast for 350 miles (560 km) from Louisville, Kentucky to Cleveland, Ohio. The route has several names including Pearl Road from Cleveland to Medina in Northeast Ohio, Reading Road in Cincinnati, Cincinnati and Lebanon Pike in southwestern Ohio and Brownsboro Road in Louisville. Traveling northeast, the highway ends in downtown Cleveland and traveling southwest ends in Louisville.
U.S. Route 68 is a United States highway that runs for 560 miles (900 km) from northwest Ohio to Western Kentucky. The highway's western terminus is at US 62 in Reidland, Kentucky. Its present eastern terminus is at Interstate 75 in Findlay, Ohio, though the route once extended as far north as Toledo. US 68 intersects with US 62 three times during its route.
Kentucky Route 80 (KY 80) is a 483.55-mile-long (778.20 km) state highway in the southern part of the U.S. state of Kentucky. The route originates on the state's western border at Columbus in Hickman County and stretches across the southern portion of the state, terminating southeast of Elkhorn City on the Virginia state line. It is the longest Kentucky State Highway, though the official distance as listed in route logs is much less due to multiple concurrencies with U.S. Route 68 (US 68) and US 23.
U.S. Route 31W is the westernmost of two parallel routes for U.S. Route 31 from Nashville, Tennessee to Louisville, Kentucky.
U.S. Route 25W (US 25W) is the western branch of US 25 from Newport, Tennessee, where US 25 splits into US 25E and US 25W, to North Corbin, Kentucky, where the two highways rejoin.
The Hal Rogers Parkway, formerly named the Daniel Boone Parkway, is a freeway connecting Somerset and Hazard in southeastern Kentucky. A former toll road, it opened in November 1971, and the tolls were removed June 1, 2003. The original extent of the highway was to be 65.70 miles (105.73 km) with that mileage to have been included with an unconstructed limited-access London bypass and what is east of this area. The original portion of the road is designated unsigned Kentucky Route 9006. An extension of the Hal Rogers Parkway name west along Kentucky Route 80 (KY 80) to U.S. Route 27 (US 27) in Somerset was made in 2015 bringing the total mileage to 91.135 miles (146.668 km).
Kentucky Route 29 is an 11.324-mile-long (18.224 km) state highway located entirely within Jessamine County in the U.S. state of Kentucky. The highway, maintained by the Kentucky Transportation Cabinet, runs north from High Bridge, Kentucky through Wilmore before ending at Nicholasville. Within Wilmore, KY 29 intersects Kentucky Route 1268 and junctions with Kentucky Route 3433. The highway acts as the border between Asbury University and Asbury Theological Seminary. Just north of Wilmore, KY 29 merges with U.S. Route 68 for 0.590 miles (0.950 km) before leaving US 68 and turning east heading towards Nicholasville. KY 29 terminates at Kentucky Route 39 and U.S. Route 27 Business in downtown Nicholasville.
Kentucky Route 44 is a 70.193 mile (112.965 km) long state highway in the U.S. state of Kentucky managed and maintained by the Kentucky Transportation Cabinet.
Kentucky Route 11 (KY 11) is an American highway maintained by the Kentucky Transportation Cabinet that runs from Maysville to Barbourville. The route from Maysville to Mount Sterling is being upgraded on a new alignment as part of a "macro-corridor" within the state of Kentucky.
Kentucky Route 79 (KY 79) is a 102-mile-long (164 km) north–south state highway that traverses five counties in west-central Kentucky. It can be seen as an extension of U.S. Route 79 (US 79), as they have the same number and once intersected; KY 79 begins in the same city that US 79 ends, and both travel on a northeast–southwest diagonal path.
U.S. Route 41 in the state of Kentucky is a north–south United States Numbered Highway that runs from Miami, Florida, to Copper Harbor, Michigan. In Kentucky, the highway is primarily paralleled by the Pennyrile Parkway and Interstate 69. It enters Kentucky in the Todd County community of Guthrie, and leaves the state north of Henderson into Evansville. The total length of US 41 through Kentucky is a total of 106.952 miles (172.123 km).
U.S. Route 150 (US 150) in Kentucky is a 121.097-mile-long (194.887 km) east–west highway that runs from the Indiana state line above the Ohio River to US 25/KY 1249 at Mount Vernon.
U.S. Route 79 enters Kentucky from Tennessee in Todd County west of Guthrie and runs northeast into Logan County, terminating at a junction with US 68, US 68 Business, and Kentucky Route 80 in Russellville. US 79 remains a two-lane road throughout Kentucky.
Kentucky Route 30 is an east–west state highway in Kentucky managed by the Kentucky Transportation Cabinet.
Kentucky Route 1681 is a 21.448-mile (34.517 km) state highway in Kentucky that runs from Kentucky Route 1659 immediately north of Millville to U.S. Route 60, Kentucky Route 922, and Manchester Street on the northwestern side of downtown Lexington.
Kentucky Route 192 (KY 192) is a 40.5-mile-long (65.2 km) state highway in the U.S. state of Kentucky. The highway connects the Somerset area and the London areas with mostly rural areas of Pulaski and Laurel counties.
Kentucky Route 229 (KY 229) is a 20.7-mile-long (33.3 km) state highway in the U.S. state of Kentucky. The highway connects rural areas of Knox and Laurel counties with London.
Kentucky Route 363 (KY 363) is a 11.105-mile-long (17.872 km) state highway in the U.S. state of Kentucky. The highway connects mostly rural areas of Laurel County with Keavy and London.
Kentucky Route 2155 is an urban secondary north–south state highway located entirely in Owensboro in northwest Kentucky.
US 25 / KY 80 / East Fifth Street in London
